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Artículo
Evaluation of toxic effects induced by repeated exposure to Cylindrospermopsin in rats using a 28-day feeding study
(Elsevier, 2021-05)
Cylindrospermopsin (CYN) is a toxin with a world-wide increasing occurrence. It can induce toxic effects both in humans and the environment, and toxicity studies are needed to complete its toxicological profile. In this ...
Artículo
In vivo genotoxicity evaluation of cylindrospermopsin in rats using a combined micronucleus and comet assay
(Elsevier, 2019)
Cylindrospermopsin (CYN) is a potent cyanotoxin recognized as an emerging human threat due to its cytotoxicity and potential carcinogenicity. Although the genotoxicity of CYN has been extensively studied in vitro, limited ...
Artículo
In vitro assessment of the combination of cylindrospermopsin and the organophosphate chlorpyrifos on the human neuroblastoma SH-SY5Y cell line
(Elsevier, 2020)
Cylindrospermopsin (CYN) is a cyanotoxicant which occurrence is increasing due to climate change. Cylindrospermopsin is able to exert damage in the organism at several levels, among them, in the nervous system. Moreover, ...
Artículo
Detection of cylindrospermopsin and its decomposition products in raw and cooked fish (Oreochromis niloticus) by analytical pyrolysis (Py-GC/MS)
(Elsevier, 2020)
The presence of the toxin cylindrospermopsin is increasingly frequent in samples from different ecosystems and it is a serious problem both at environmental level and for animal and human health. To be able to prevent CYN ...
Artículo
Changes on cylindrospermopsin concentration and characterization of decomposition products in fish muscle (Oreochromis niloticus) by boiling and steaming
(Elsevier, 2017)
The occurrence of cylindrospermopsin (CYN) in toxic blooms of cyanobacteria is increasing in both frequency and distribution over the world. CYN persistence in water potentiates its accumulation in a wide range of aquatic ...
Artículo
In vitro assessment of cyanotoxins bioaccessibility in raw and cooked mussels
(Elsevier, 2020)
The oral route by ingestion of water and food contaminated with cyanotoxins is the main route of exposure to these toxins. This study addresses for the first time the bioaccessibility of some of the most common Microcystins ...
Artículo
Mutagenic and genotoxic potential of pure Cylindrospermopsin by a battery of in vitro tests
(Elsevier, 2018)
Cylindrospermopsin (CYN) is a cyanobacterial toxin with an increasing world-wide occurrence. The main route of human exposure is through the ingestion of contaminated food and water. The European Food Safety Authority has ...
Artículo
In vitro toxicological assessment of cylindrospermopsin: A review
(Multidisciplinary Digital Publishing Institute (MDPI), 2017)
Cylindrospermopsin (CYN) is a cyanobacterial toxin that is gaining importance, owing to its increasing expansion worldwide and the increased frequency of its blooms. CYN mainly targets the liver, but also involves other ...
Artículo
Bioaccessibility and decomposition of cylindrospermopsin in vegetablesmatrices after the application of anin vitrodigestion model
(Elsevier, 2018)
Research on the human exposure to Cylindrospermopsin (CYN) via consumption of contaminated food is of great interest for risk assessment purposes. The aim of this work is to evaluate for the first time the CYN bioaccessibility ...
Artículo
Intestinal transport of Cylindrospermopsin using the Caco-2 cell line
(Elsevier, 2017)
Cylindrospermopsin (CYN) is a cyanotoxin produced by various cyanobacterial species. It is a water soluble zwitterion, stable at extreme temperatures and pH. Despite the main route of exposure to CYN is through drinking ...