Capítulos (Bioquímica Vegetal y Biología Molecular)
URI permanente para esta colecciónhttps://hdl.handle.net/11441/10825
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Capítulo de Libro Biosíntesis de carotenoides: consideraciones generales(Terracota, 2017) Ruiz Sola, M. Águila; Rodríguez Concepción, Manuel; Universidad de Sevilla. Departamento de Bioquímica Vegetal y Biología MolecularCapítulo de Libro El centro de reacción fotosintético: Un sistema biológico convertidor de energía lumínica en energía química(Real Academia Sevillana de Ciencias, 2002) Ortega Rodríguez, José María; Universidad de Sevilla. Departamento de Bioquímica Vegetal y Biología MolecularArtículo Sustaining Rice Production through Biofertilization with N2-Fixing Cyanobacteria(MDPI, 2021) Iniesta Pallarés, Macarena; Álvarez Núñez, Consolación; Gordillo Cantón, Francisco M.; Ramírez Moncayo, Carmen; Alves Martínez, Pilar; Molina Heredia, Fernando Publio; Mariscal, Vicente; Universidad de Sevilla. Departamento de Bioquímica Vegetal y Biología Molecular; Corporación Tecnológica de Andalucía (CTA). España; Universidad de SevillaCurrent agricultural productivity depends on an exogenous nutrient supply to crops. This is of special relevance in cereal production, a fundamental part of the trophic chain that plays a vital role in the human diet. However, our agricultural practices entail highly detrimental side-effects from an environmental point of view. Long-term nitrogen fertilization in croplands results in degradation of soil, water, and air quality, producing eutrophication and subsequently contributing to global warming. In accordance with this, there is a biotechnological interest in using nitrogen-fixing microorganisms to enhance crop growth without adding chemically synthesized nitrogen fertilizers. This is particularly beneficial in paddy fields, where about 60% of the synthetic fertilizer that has been applied is dissolved in the water and washed away. In these agricultural systems, N2-fixing cyanobacteria show a promising biotechnological potential as biofertilizers, improving soil fertility while reducing the environmental impact of the agricultural practice. In the current study, Andalusian paddy fields have been explored to isolate N2-fixing cyanobacteria. These endogenous microorganisms have been subsequently re-introduced in a field trial in order to enhance rice production. Our results provide valuable insights regarding the use of an alternative natural source of nitrogen for rice production.Artículo Breast tumor cells promotes the horizontal propagation of EMT, stemness, and metastasis by transferring the MAP17 protein between subsets of neoplastic cells(Springer Nature, 2020) García Heredia, José Manuel; Otero Albiol, Daniel; Pérez, Marco; Pérez Castejón, Elena; Muñoz Galván, Sandra; Carnero, Amancio; Universidad de Sevilla. Departamento de Bioquímica Vegetal y Biología Molecular; Ministerio de Ciencia, Innovación y Universidades (MICINN). España; Agencia Estatal de Investigación. España; European Commission (EC). Fondo Europeo de Desarrollo Regional (FEDER); entro de Investigación Biomédica en Red (CIBER). España; Junta de AndalucíaMAP17 (PDZK1IP1) is a small protein regulating inflammation and tumor progression, upregulated in a broad range of carcinomas. MAP17 levels increase during tumor progression in a large percentage of advanced tumors. In the present work, we explored the role of this protein shaping tumor evolution. Here we show that in breast cancer, cells increased MAP17 levels in tumors by demethylation induced multiple changes in gene expression through specific miRNAs downregulation. These miRNA changes are dependent on Notch pathway activation. As a consequence, epithelial mesenchymal transition (EMT) and stemness are induced promoting the metastatic potential of these cells both in vitro and in vivo. Furthermore, MAP17 increased the exosomes in tumor cells, where MAP17 was released as cargo, and this horizontal propagation also increased the EMT in the recipient cells. Importantly, an antibody against MAP17 in the media reduces the EMT and stemness alterations promoted by the conditioned media from MAP17-expressing cells. Therefore, MAP17 expression promotes the horizontal propagation of EMT and metastasis by transferring the MAP17 protein between subsets of neoplastic cells. Thus, MAP17 can be used to describe a new mechanism for cell malignity at distance, without the involvement of genetic or epigenetic modifications. MAP17 can also be taken in consideration as new target for metastatic high-grade breast tumors.Capítulo de Libro Localization and Regulation of Phosphoenolpyruvate Carboxylase from Wheat and Barley Seeds(Institut de Biotechnologie des Plantes, 1998) Echevarría Ruiz de Vargas, Cristina; Osuna Beviá, Lidia; González García, María de la Cruz; Álvarez Morales, Rosario; Pierre, Jean-Nöel; Vidal, Jean; Cejudo Fernández, Francisco Javier; Universidad de Sevilla. Departamento de Biología Vegetal y Ecología; Universidad de Sevilla. Departamento de Bioquímica Vegetal y Biología Molecular; Gadal, P.; Kreis, M.; Dron, M.; Brulfert, J.; Bergounioux, C.; Vidal, J.Capítulo de Libro Genetic, biochemical and physiological evidence of the widespread distribution of K+-dependent and K+-independent proton-translocating pyrophosphatases(Universidad de Sevilla-CSIC, 2001) Losada Villasante, Manuel; Universidad de Sevilla. Departamento de Bioquímica Vegetal y Biología Molecular; Serrano Delgado, AurelioCapítulo de Libro On the chimeric nature of the soluble pyrophosphatases set from photosynthetic eukaryotes(Universidad de Sevilla-CSIC, 2001) Losada Villasante, Manuel; Universidad de Sevilla. Departamento de Bioquímica Vegetal y Biología Molecular; Serrano Delgado, AurelioCapítulo de Libro The function of the oxide anion in the bioenergetics of pyrophosphate(Universidad de Sevilla-CSIC, 2001) Losada Villasante, Manuel; Universidad de Sevilla. Departamento de Bioquímica Vegetal y Biología Molecular; Serrano Delgado, AurelioCapítulo de Libro Mis bodas de oro con la biología(Farmaindustria, 2004) Losada Villasante, Manuel; Universidad de Sevilla. Departamento de Bioquímica Vegetal y Biología MolecularCapítulo de Libro Discurso del Dr. Losada Villasante. Acto de investidura como Honoris Causa por la Universidad de Córdoba(Prensas Universitarias de Zaragoza, 2010) Losada Villasante, Manuel; Universidad de Sevilla. Departamento de Bioquímica Vegetal y Biología Molecular