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Listar por autor "Romero Balestra, Fernando"
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Artículo
A novel biocompatible polymer derived from D-mannitol used as a vector in the field of genetic engineering of eukaryotic cells
Pérez, David; Moyá Morán, María Luisa; Bautista, María; León, Rosa; Molina-Márquez, Ana; Vila, Marta; Romero Azogil, Lucía; Benito Hernández, Elena María; García Martín, María de Gracia; Valle Rosado, Iván; Romero Balestra, Fernando; Huertas Sánchez, Pablo; López-Cornejo, María del Pilar (Elsevier Science BV, 2023-02-23)The design and preparation of new vectors to transport genetic material and increase the transfection efficiency continue ...
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Artículo
Centriolar Subdistal Appendages Promote Double-strand Break Repair Through Homologous Recombination
Rodriguez Real, Guillermo; Domínguez Calvo, Andrés; Prados Carvajal, Rosario; Bayona Feliu, Aleix; Gomes Pereira, Sonia; Romero Balestra, Fernando; Huertas Sánchez, Pablo (1469-3178, 2023)The centrosome is a cytoplasmic organelle with roles in microtu-bule organization that has also been proposed to act as a ...
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Artículo
Metallo-Liposomes of Ruthenium Used as Promising Vectors of Genetic Material
Lebrón Romero, José Antonio; Ostos Marcos, Francisco José; López López, Manuel; Moyá Morán, María Luisa; Sales, Carlos; García, Encarnación; García Calderón, Clara Beatriz; García Calderón, Margarita; Peña Gómez, Mª José; Valle Rosado, Iván; Romero Balestra, Fernando; Huertas Sánchez, Pablo; López-Cornejo, María del Pilar (MDPI, 2020)Gene therapy is a therapeutic process consisting of the transport of genetic material into cells. The design and preparation ...
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Artículo
Multivalent Calixarene-Based Liposomes as Platforms for Gene and Drug Delivery
Lebrón Romero, José Antonio; López López, Manuel; García Calderón, Clara Beatriz; Valle Rosado, Iván; Romero Balestra, Fernando; Huertas Sánchez, Pablo; Rodik, Roman V; Kalchenko, Vitaly I.; Bernal Pérez, Eva; Moyá Morán, María Luisa; López-Cornejo, María del Pilar; Ostos Marcos, Francisco José (MDPI, 2021-08)The formation of calixarene-based liposomes was investigated, and the characterization of these nanostructures was carried ...
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Artículo
Sperm-contributed centrioles segregate stochastically into blastomeres of 4-cell stage Caenorhabditis elegans embryos
Gönczy, Pierre; Romero Balestra, Fernando (Oxford University Press, 2023-03-29)Whereas both sperm and egg contribute nuclear genetic material to the zygote in metazoan organisms, the inheritance of ...
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Artículo
The Emerging Role of RNA Modifications in DNA Double-Strand Break Repair
Jimeno González, Sonia; Romero Balestra, Fernando; Huertas Sánchez, Pablo (Frontiers Media S.A., 2021)The correct repair of DNA double-strand breaks is essential for maintaining the stability of the genome, thus ensuring the ...
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Artículo
TRIM37 prevents formation of centriolar protein assemblies by regulating Centrobin
Romero Balestra, Fernando; Domínguez Calvo, Andrés; Wolf, Benita; Busso, Coralie; Buff, Alizée; Averink, Tessa; Lipsanen Nyman, Marita; Huertas Sánchez, Pablo; Rios Sánchez, Rosa M.; Gönczy, Pierre (eLife Sciences Publications, 2021)TRIM37 is an E3 ubiquitin ligase mutated in Mulibrey nanism, a disease with impaired organ growth and increased tumor ...
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Tesis Doctoral
Unraveling the connection between centrosomes and the DNA damage response
Rodríguez Real, Guillermo (2023-06-20)Centrosomes act as the major microtubule (MT) organizing centers (MTOC) in most animal cells. Structural or numerical defects in this organelle are associated with ...