- idUS
- Browsing by Author
Browsing by Author "Ortega Sáenz, Patricia"
Now showing items 21-26 of 26
-
Article
Selective accumulation of biotin in arterial chemoreceptors: requirement for carotid body exocytotic dopamine secretion
Ortega Sáenz, Patricia; Macías Gutiérrez, David; Levitsky, Konstantin L.; Rodríguez Gómez, José Antonio; González Rodríguez, Patricia; Bonilla Henao, Victoria; Arias-Mayenco, Ignacio; López Barneo, José (2016-12)Biotin is a water-soluble vitamin required for the function of carboxylases as well asfor the regulation of gene expression. ...
-
Article
The carotid body, a neurogenic niche in the adult peripheral nervous system
Pardal Redondo, Ricardo; Ortega Sáenz, Patricia; Durán, Rocío; Platero-Luengo, Aida; López Barneo, José (Univ pisa, 2010)We have described a new population of adult neural stem cells residing in the carotid body, a chemoreceptor organ in the ...
-
Article
The Mitochondrial SDHD Gene Is Required for Early Embryogenesis, and Its Partial Deficiency Results in Persistent Carotid Body Glomus Cell Activation with Full Responsiveness to Hypoxia
Piruat Palomo, José Ignacio; Óscar Pintado, Carmelo; Ortega Sáenz, Patricia; Roche Molina, Marta; López Barneo, José (2004)The SDHD gene encodes one of the two membrane-anchoring proteins of the succinate dehydrogenase (complex II) of the ...
-
Article
Transgenic NADH dehydrogenase restores oxygen regulation of breathing in mitochondrial complex I-deficient mice
Jiménez Gómez, Blanca; Ortega Sáenz, Patricia; Gao Chen, Lin; González Rodríguez, Patricia; García-Flores, Paula; Chandel, Navdeep; López Barneo, José (NATURE PUBLISHING GROUP, 2023)The hypoxic ventilatory response (HVR) is a life-saving reflex, triggered by the activation of chemoreceptor glomus cells ...
-
Article
Unexpected obesity, rather than tumorigenesis, in a conditional mouse model of mitochondrial complex II deficiency
Al Khazal, Fatimah; Seungwoo, Kang; Holte, Molly Nelson; Choi, Doo-Sup; Singh, Ravinder; Ortega Sáenz, Patricia; López Barneo, José; Maher III, James L. (Federation amer soc exp biol, 2021)Mutations in any of the genes encoding the four subunits of succinate dehydrogenase (SDH), a mitochondrial membrane-bound ...
-
Article
Using redox-sensitive fluorescent probes to record real-time reactive oxygen species production in cells from mouse carotid body slices
Gao Chen, Lin; Arias-Mayenco, Ignacio; Ortega Sáenz, Patricia; López Barneo, José (Cell Press, 2021)Reactive oxygen species (ROS) are important signaling molecules for physiologic processes such as acute response to ...