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Listar por autor "Moreno Vargas, Antonio José"
Mostrando ítems 21-29 de 29
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Artículo
Synthesis and Biological Evaluation of Modified 2-Deoxystreptamine Dimers
Coste, G.; Horlacher, T.; Molina Sanz, Lidia; Moreno Vargas, Antonio José; Carmona Asenjo, Ana Teresa; Robina Ramírez, Inmaculada; Seeberger, P.H.; Gerber-Lemaire, S. (Thieme Publishing; Georg Thieme Verlag, 2011)Aminoglycosides are powerful antibiotics, but the emergence of resistant bacterial strains has prompted the search for ...
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Artículo
Synthesis and cancer growth inhibitory activities of 2-fatty-alkylated pyrrolidine-3,4-diol derivatives
Elías Rodríguez, María del Pilar; Moreno Clavijo, Elena; Carrión Jiménez, Sebastián; Carmona Asenjo, Ana Teresa; Moreno Vargas, Antonio José; Caffa, I.; Montecucco, F.; Cea, M.; Nencioni, A.; Robina Ramírez, Inmaculada (Arkat USA, 2014)A series of new amphiphilic pyrrolidines containing dodecyl and oleyl apolar side chains were prepared and evaluated for ...
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Artículo
Synthesis and Structure-activity Relationship of New Nicotinamide Phosphoribosyltransferase Inhibitors with Antitumor Activity on Solid and Haematological Cancer
Fratta, Simone; Biniecka, Paulina; Moreno Vargas, Antonio José; Carmona Asenjo, Ana Teresa; Nahimana, Aimable; Duchosal, Michel A.; Piacente, Francesco; Bruzzone, Santina; Caffa, Irene; Nencioni, Alessio; Robina Ramírez, Inmaculada (Elsevier, 2023)Cancer cells are highly dependent on Nicotinamide phosphoribosyltransferase (NAMPT) activity for proliferation, therefore ...
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Tesis Doctoral
Synthesis of new nampt inhibitors as potential anti-cancer drugs. An approach to antibody-drug conjugates
Fratta, Simone (2023-01-27)Nicotinamide phosphoribosyltransferase (NAMPT) catalyzes the rate-limiting step in the biosynthesis of Nicotinamide Adenine ...
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Artículo
Synthesis of Novel 3-Amino(Hydroxy)methyl-l-fuco-Azafagomines as Leads for Selective Inhibitors of α-l-Fucosidases
Moreno Clavijo, Elena; Carmona Asenjo, Ana Teresa; Moreno Vargas, Antonio José; Álvarez González, Eleuterio; Robina Ramírez, Inmaculada (2010)The synthesis of 3-substituted l-fuco-azafagomines from d-lyxose is reported. They represent the first example of ...
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Patente. Invención
Tiofucósidos conteniendo polihidroxialquil-furanos, síntesis y usos de los mismos
Moreno Vargas, Antonio José; Molina Sanz, Lidia; Carmona Asenjo, Ana Teresa; Lambelet, Martine; Spertini, Olivier; Robina Ramírez, Inmaculada (Oficina Española de Patentes y Marcas (OEPM), 2010-02-12)Tiofucósidos conteniendo polihidroxialquil-furanos, síntesis y usos de los mismos. Compuesto que comprende un tiofucósido ...
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Patente. Invención
Tiofucósidos conteniendo prolinas hidroxiladas, síntesis y usos de los mismos
Moreno Vargas, Antonio José; Molina Sanz, Lidia; Carmona Asenjo, Ana Teresa; Lambelet, Martine; Spertini, Oliver; Robina Ramírez, Inmaculada (Oficina Española de Patentes y Marcas (OEPM), 2010-02-12)Tiofucósidos conteniendo prolinas hidroxiladas, síntesis y usos de los mismos. Compuesto que comprende un tiofucósido ...
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Artículo
Total asymmetric synthesis of monosaccharides and analogues
Robina Ramírez, Inmaculada; Carmona Asenjo, Ana Teresa; Moreno Vargas, Antonio José; Moreno Clavijo, Elena (Schweizerische Chemische Gesellschaft (Swiss Chemistry Society), 2011)Since the discovery of the 'formose reaction' by Butlerow,[1] total synthesis of carbohydrates has undergone rapid ...
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Artículo
Transferring Substituents from Alkynes to Furans and Pyrroles through Heteronorbornadienes as Intermediates: Synthesis of β-Substituted Pyrroles/Furans
García Domínguez, Javier; Carranza César, Marina; Jansons, Edijs; Carmona Asenjo, Ana Teresa; Robina Ramírez, Inmaculada; Moreno Vargas, Antonio José (American Chemical Society, 2023)The use of 7-oxa/azanorbornadienes as synthetic intermediates for the preparation of 3/4-substituted (β-substituted) ...