idUS - Perfil del autor: Bachiller, Sara

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Nombre	Bachiller, Sara
Departamento	Bioquímica Médica y Biología Molecular e Inmunología
Área de conocimiento	Bioquímica y Biología Molecular
Categoría profesional	Investigadora Contratada (Ramón y Cajal)
Correo electrónico	Solicitar

Nº publicaciones

12
Nº visitas

1066
Nº descargas

1100

Tipología

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Publicaciones
Artículo LPS priming before plaque deposition impedes microglial activation and restrains Abeta pathology in the 5xFAD mouse model of Alzheimer's disease. Yang, Yiyi; García Cruzado, Marta; Zeng, Hairuo; Camprubi Ferrer, Lluis; Bahatyrevich Kharitonik, Bazhena; Bachiller, Sara; Deierborg, Tomas (Elsevier, 2023) Microglia have an innate immunity memory (IIM) with divergent functions in different animal models of neurodegenerative ...
Artículo A metagenome-wide association study of HIV disease progression in HIV controllers Real, Luis Miguel; Sáez, María E.; Corma Gómez, Anaïs; González Pérez, Antonio; Thorball, Christian; Ruiz Laza, Rocío; Jiménez León, María Reyes; González-Serna Martín, Manuel Alejandro; Bachiller, Sara; Ruiz Mateos, Ezequiel (Elsevier, 2023) Some HIV controllers experience immunologic progression with CD4+ T cell decline. We aimed to identify genetic factors ...
Artículo Targeting galectin-3 to counteract spike-phase uncoupling of fast-spiking interneurons to gamma oscillations in Alzheimer’s disease Bachiller, Sara; Ruiz Laza, Rocío; Boza Serrano, Antonio; Rodríguez-Moreno, Antonio; Deierborg, Tomas; Fisahn, André (2023) Background Alzheimer’s disease (AD) is a progressive multifaceted neurodegenerative disorder for which no disease-modifying ...
Artículo Early-life stress elicits peripheral and brain immune activation differently in wild type and 5xFAD mice in a sex-specific manner Bachiller, Sara; Hidalgo, Isabel; Garcia, M. G.; Boza Serrano, Antonio; Paulus, Agnes; Denis, Q.; Haikal, C.; Manouchehrian, O.; Klementieva, O.; Li, J. Y.; Pronk, C. J.; Gouras, G. K.; Deierborg, Tomas (BMC, 2022) Background The risk of developing Alzheimer’s disease (AD) is modulated by genetic and environmental factors. Early-life ...
Artículo Immune defects associated with lower SARS-CoV-2 BNT162b2 mRNA vaccine response in aged people Vitalle, Joana; Pérez Gómez, Alberto; Ostos Marcos, Francisco José; Gasca-Capote, Carmen; Jiménez León, María Reyes; Bachiller, Sara; López Cortés, Luis Fernando; Rafii-El-Idrissi Benhnia, Mohammed; Ruiz Mateos, Ezequiel (Journal of clinical investigation, 2022) The immune factors associated with impaired SARS-CoV-2 vaccine response in elderly people are mostly unknown. We studied ...
Artículo Acute systemic LPS-exposure impairs perivascular CSF distribution in mice Manouchehrian, O.; Ramos, M.; Bachiller, Sara; Lundgaard, I.; Deierborg, T. (Biomed Central LTD, 2021) The exchange of cerebrospinal (CSF) and interstitial fluid is believed to be vital for waste clearance in the brain. The ...
Artículo The Other Side of SARS-CoV-2 Infection: Neurological Sequelae in Patients Alonso Bellido, Isabel María; Bachiller, Sara; Vázquez, Guillermo; Cruz Hernández, Luis; Martínez, Emilio; Ruiz Mateos, Ezequiel; Deierborg, Tomas; Venero Recio, José Luis; Real, Luis Miguel; Ruiz Laza, Rocío (Frontiers Media S.A., 2021) The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread around the globe causing coronavirus disease ...
Artículo The effect of electroconvulsive therapy on neuroinflammation, behavior and amyloid plaques in the 5xFAD mouse model of Alzheimer's disease Svensson, M; Olsson, G; Yang, YY; Bachiller, Sara; Ekemohn, M; Deierborg, T (Nature Publishing Group, 2021) Microglial cells are affected in Alzheimer’s disease (AD) and interact with amyloid-beta (Aβ) plaques. Apart from memory ...
Artículo The HERC proteins and the nervous system Pérez Villegas, Eva María; Ruiz Laza, Rocío; Bachiller, Sara; Ventura, Francesc; Armengol, Jose A.; Rosa, Jose Luis (Elsevier, 2021) The HERC protein family is one of three subfamilies of Homologous to E6AP C-terminus (HECT) E3 ubiquitin ligases. Six HERC ...
Artículo The Ubiquitin Proteasome System in Neuromuscular Disorders: Moving Beyond Movement Bachiller, Sara; Alonso Bellido, Isabel María; Real, Luis Miguel; Pérez Villegas, Eva María; Venero Recio, José Luis; Deierborg, Tomas; Armengol, José Ángel; Ruiz Laza, Rocío (Multidisciplinary Digital Publishing Institute (MDPI), 2020) Neuromuscular disorders (NMDs) affect 1 in 3000 people worldwide. There are more than 150 different types of NMDs, where ...
Artículo HERC1 Ubiquitin Ligase Is Required for Normal Axonal Myelination in the Peripheral Nervous System Bachiller, Sara; Roca Ceballos, María Angustias; García Domínguez, Irene; Pérez Villegas, Eva María; Martos Carmona, David; Pérez Castro, Miguel Ángel; Real Navarrete, Luis Miguel; Rosa, José Luis; Tabares, Lucía; Venero Recio, José Luis; Armengol, José Ángel; Carrión, Ángel Manuel; Ruiz Laza, Rocío (Springer, 2018) A missense mutation in HERC1 provokes loss of cerebellar Purkinje cells, tremor, and unstable gait in tambaleante (tbl) ...
Artículo HERC 1 Ubiquitin Ligase Mutation Affects Neocortical, CA3 Hippocampal and Spinal Cord Projection Neurons: An Ultrastructural Study Ruiz Laza, Rocío; Pérez Villegas, Eva María; Bachiller, Sara; Rosa, José Luis; Armengol, Jose Ángel (Frontiers Media, 2016) The spontaneous mutation tambaleante is caused by the Gly483Glu substitution in the highly conserved N terminal RCC1-like ...