idUS - Author profile: Boza Serrano, Antonio

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Name	Boza Serrano, Antonio
Department	Bioquímica y Biología Molecular
Knowledge area	Bioquímica y Biología Molecular
Professional category	Contrato Juan de la Cierva Incorporación
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14
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Publications
Article Inflammatory bowel disease induces pathologicalα-synucleinaggregation in the human gut and brain Espinosa Oliva, Ana María; Ruiz Laza, Rocío; Sarmiento Soto, Manuel; Boza Serrano, Antonio; Rodríguez Pérez, Ana I; Roca Ceballos, María Angustias; García Revilla, Juan; Santiago Pavón, Martiniano; Carvajal Vázquez, Ana Eloísa; Vázquez Carretero, María Dolores; García Miranda, Pablo; Oliva Martin, María José; Machado Quintana, Alberto; Peral Rubio, María José; Herrera Carmona, Antonio José; Venero Recio, José Luis; Martínez de Pablos, Rocío; neuroinflammation (Wiley, 2024) Aims According to Braak's hypothesis, it is plausible that Parkinson's disease (PD) originates in the enteric nervous ...
Article Galectin-3 is upregulated in frontotemporal dementia patients with subtype specificity Borrego Écija, Sergi; Pérez Millan, Agnès; Antonell, Anna; Fort Aznar, Laura; Kaya Tilki, Elif; León Halcón, Alberto; Vitorica Ferrández, Francisco Javier; Venero Recio, José Luis; Boza Serrano, Antonio (Wiley, 2023) INTRODUCTION Neuroinflammation is a major contributor to the progression of frontotemporal dementia (FTD). Galectin-3 ...
Article Galectin-3 shapes toxic alpha-synuclein strains in Parkinson's disease. García Revilla, Juan; Boza Serrano, Antonio; Jin, Yiyun; Vadukul, Devkee M.; Soldán Hidalgo, Jesús; Camprubí Ferrer, Lluís; Ruiz Laza, Rocío; Venero Recio, José Luis (Springer, 2023) Parkinson’s Disease (PD) is a neurodegenerative and progressive disorder characterised by intracytoplasmic inclusions ...
Article Targeting galectin-3 to counteract spike-phase uncoupling of fast-spiking interneurons to gamma oscillations in Alzheimer’s disease Bachiller, Sara; Ruiz Laza, Rocío; Boza Serrano, Antonio; Rodríguez-Moreno, Antonio; Deierborg, Tomas; Fisahn, André (2023) Background Alzheimer’s disease (AD) is a progressive multifaceted neurodegenerative disorder for which no disease-modifying ...
Article Early-life stress elicits peripheral and brain immune activation differently in wild type and 5xFAD mice in a sex-specific manner Bachiller, Sara; Hidalgo, Isabel; Garcia, M. G.; Boza Serrano, Antonio; Paulus, Agnes; Denis, Q.; Haikal, C.; Manouchehrian, O.; Klementieva, O.; Li, J. Y.; Pronk, C. J.; Gouras, G. K.; Deierborg, Tomas (BMC, 2022) Background The risk of developing Alzheimer’s disease (AD) is modulated by genetic and environmental factors. Early-life ...
Article APOE in the bullseye of neurodegenerative diseases: impact of the APOE genotype in Alzheimer’s disease pathology and brain diseases Fernández Calle, R.; Konings, Sabine C.; Frontinan Rubio, Javier; Garcia Revilla, Juan; Camprubí Ferrer, Lluís; Svensson, Martina; Martinson, Isak; Boza Serrano, Antonio; Venero Recio, José Luis; Nielsen, Henrietta M.; Gouras, Gunnar K.; Deierborg, Tomas (Springer Nature, 2022) ApoE is the major lipid and cholesterol carrier in the CNS. There are three major human polymorphisms, apoE2, apoE3, and ...
Article Galectin-3 is elevated in CSF and is associated with A beta deposits and tau aggregates in brain tissue in Alzheimer's disease Boza Serrano, Antonio; Vrillon, Agathe; Minta, Karolina; Paulus, Agnes; Camprubí Ferrer, Lluís; García, Megg; Vitorica Ferrández, Francisco Javier; Venero Recio, José Luis; Deierborg, Tomas (Springer, 2022) Galectin-3 (Gal-3) is a beta-galactosidase binding protein involved in microglial activation in the central nervous ...
Article Galectin-3, a rising star in modulating microglia activation under conditions of neurodegeneration García Revilla, Juan; Boza Serrano, Antonio; Espinosa Oliva, Ana María; Sarmiento Soto, Manuel; Deierborg, Tomas; Ruiz Laza, Rocío; Martínez de Pablos, Rocío; Burguillos García, Miguel Ángel; Venero Recio, José Luis (Springer Nature, 2022) The advent of high-throughput single-cell transcriptomic analysis of microglia has revealed different phenotypes that are ...
Article The human bone marrow harbors a CD45− CD11B+ cell progenitor permitting rapid microglia-like cell derivative approaches Bruzelius, Andreas; Hidalgo, Isabel; Boza Serrano, Antonio; Hjelmér, Anna Giorgia; Tison, Amelie; Deierborg, Tomas; Bengzon, Johan; Ramos Moreno, Tania (Wiley-Blackwell, 2021) Microglia, the immune sentinel of the central nervous system (CNS), are generated from yolk sac erythromyeloid progenitors ...
Article Hyperinflammation and Fibrosis in Severe COVID-19 Patients: Galectin-3, a Target Molecule to Consider García Revilla, Juan; Deierborg, Tomas; Venero Recio, José Luis; Boza Serrano, Antonio (Frontiers Media, 2020) COVID-19 disease have become so far the most important sanitary crisis in the XXI century. In light of the events, any ...
Article Galectin‑3, a novel endogenous TREM2 ligand, detrimentally regulates infammatory response in Alzheimer’s disease Boza Serrano, Antonio; Ruíz Laza, Rocio; Sánchez Varo, Raquel María; García Revilla, Juan; Yang, Yiyi; Jiménez Ferrer, Itzia; Jiménez Muñoz, Sebastián; Roca Ceballos, María Angustias; Navarro Garrido, Victoria; Vitorica Ferrández, Francisco Javier; Venero Recio, José Luis; Deierborg, Tomas (Springer, 2019) Alzheimer’s disease (AD) is a progressive neurodegenerative disease in which the formation of extracellular aggregates of ...
Article Divergent Effects of Metformin on an Inflammatory Model of Parkinson’s Disease Tayara, Khadija; Espinosa Oliva, Ana María; García Domínguez, Irene; Ismaiel, Afrah Abdul; Boza Serrano, Antonio; Deierborg, Tomas; Martínez de Pablos, Rocío; Machado de la Quintana, Alberto; Herrera Carmona, Antonio José; Venero Recio, José Luis (Frontiers Media, 2018) The oral antidiabetic drug metformin is known to exhibit anti-inflammatory properties through activation of AMP kinase, ...
Article Microglia-secreted galectin-3 acts as a toll-like receptor 4 ligand and contributes to microglial activation Burguillos García, Miguel Ángel; Svensson, Martina; Schulte, Tim; Boza Serrano, Antonio; García Quintanilla, Alberto; Kavanagh, Edel T.; Santiago Pavón, Martiniano; Viceconte, Nikenza; Oliva Martín, María José; Osman, Ahmed Mohamed; Salomonsson, Emma; Amar, Lahouari; Persson, Annette; Blomgren, Klas; Achour, Adnane; Englund, Elisabet; Leffler, Hakon; Venero Recio, José Luis; Joseph, Bertrand; Deierborg, Tomas (2015) Inflammatory response induced by microglia plays a critical role in the demise of neuronal populations in neuroinflammatory ...
Article The role of Galectin-3 in α-synuclein-induced microglial activation Boza Serrano, Antonio; Reyes, Juan F.; Rey, Nolwen L.; Leffler, Hakon; Bousset, Luc; Nilsson, Ulf J.; Brundin, Patrik; Venero Recio, José Luis; Burguillos García, Miguel Ángel; Deierborg, Tomas (BioMed Central, 2014) Background: Parkinson ’ s disease (PD) is the most prevalent neurodegenerative motor disorder. The neuropathology ...