NameMuñoz Pinto, Mario Faustino
DepartmentBioquímica y Biología Molecular
Knowledge areaBioquímica y Biología Molecular
Professional categoryProfesor Permanente Laboral - Mod. PCD
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    21

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The Emerging Role of Senotherapy in Cancer: A Comprehensive Review

Malayaperumal, Sarubala; Marotta, Francesco; Kumar, Makalakshmi Murali; Somasundaram, Indumathi; Ayala Gómez, Antonio; Muñoz Pinto, Mario Faustino; Banerjee, Antara; Pathak, Surajit (MDPI, 2023)
Senotherapy, a promising therapeutic strategy, has drawn a lot attention recently due to its potential for combating cancer. ...
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The Neurokinin-1 Receptor Is Essential for the Viability of Human Glioma Cells: A Possible Target for Treating Glioblastoma

Muñoz Pinto, Mario Faustino; Argüelles Castilla, Sandro; Rosso, Marisa; Medina, Rafael; Coveñas, Rafael; Ayala Gómez, Antonio; Muñoz, Miguel (Hindawi, 2022)
Background. Glioblastoma or glioma is the most common malignant brain tumor. Patients have a prognosis of approximately ...
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Irisin enhances longevity by boosting SIRT1, AMPK, autophagy and telomerase

Sánchez Aliena; Muñoz Pinto, Mario Faustino; Cano Rodríguez, Mercedes (Cambridge University Press, 2022)
Ageing is characterised by the accumulation of molecular and cellular damage through time, leading to a decline in physical ...
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Effect of Age and Lipoperoxidation in Rat and Human Adipose Tissue-Derived Stem Cells

Muñoz Pinto, Mario Faustino; Argüelles Castilla, Sandro; Marotta, Francesco; Barbagallo, M.; Cano Rodríguez, María Mercedes; Ayala Gómez, Antonio (Hindawi, 2020)
A wide range of clinical applications in regenerative medicine were opened decades ago with the discovery of adult stem ...
Patent. Invention
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Kit y método de cuantificación de la toxicidad en neuronas de la corteza cerebral para la detección de enfermedades neurodegenerativas

Núñez Abades, Pedro Antonio; Carrascal Moreno, María Livia; Pardilla Díaz, Ricardo; Cano Rodríguez, María Mercedes; Muñoz Pinto, Mario Faustino; Ayala Gómez, Antonio (Oficina Española de Patentes y Marcas (OEPM), 2019)
La presente invención escribe un método electrofisiológico y un kit consistente en una concentración de 10 µM de hidroperóxido ...
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Dysregulation of the Hippo Pathway Signaling in Aging and Cancer

Yeung, Yiu To; Guerrero Castilla, Angelica; Cano Rodríguez, María Mercedes; Muñoz Pinto, Mario Faustino; Ayala Gómez, Antonio; Argüelles Castilla, Sandro (Elsevier, 2019)
Human beings are facing emerging degenerative and cancer diseases, in large part, as a consequence of increased life ...
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Advantages and Disadvantages of Apoptosis in the Aging Process

Argüelles Castilla, Sandro; Guerrero Castilla, Angélica; Cano Rodríguez, María Mercedes; Muñoz Pinto, Mario Faustino; Ayala Gómez, Antonio (Wiley-Blackwell, 2019)
Researchers cannot predict as yet how long a human being can live. Life expectancy has been steadily increasing in the ...
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Cell Tracking, Survival, and Differentiation Capacity of Adipose-Derived Stem Cells After Engraftment in Rat Tissue

Muñoz Pinto, Mario Faustino; Argüelles Castilla, Sandro; Guzmán Chozas, Matías; Guillén Sans, Remedios; Franco, Jaime M.; Pintor Toro, José A.; Cano Rodríguez, María Mercedes; Ayala Gómez, Antonio (Wiley-Blackwell, 2018)
Adipose tissue is an important source of adipose derived stem cells (ADSCs). These cells have the potential of being used ...
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Immunolocalization of Substance P and NK-1 Receptor in ADIPOSE Stem Cells

Muñoz, Miguel; Muñoz Pinto, Mario Faustino; Ayala Gómez, Antonio (Wiley-Blackwell, 2017)
Substance P (SP) is a neuropeptide belonging to the thachykinin peptide family. SP, after binding to its receptor, the ...
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Aging and Oxidative Stress Decrease Pineal Elongation Factor 2: In Vivo Protective Effect of Melatonin in Young Rats Treated With Cumene Hydroperoxide

Muñoz Pinto, Mario Faustino; Argüelles Castilla, Sandro; Cano Rodríguez, María Mercedes; Marotta, Francesco; Ayala Gómez, Antonio (Wiley-Blackwell, 2017)
We studied the alterations of Elongation Factor 2 (eEF2) in the pineal gland of aged rats as well as the possible protective ...
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Hialuronic acid in sking aging

Serres, José; Cano Rodríguez, María Mercedes; Muñoz Pinto, Mario Faustino; Argüelles Castilla, Sandro; Ayala Gómez, Antonio; Ayala Gómez, Antonio (Spanish Society of Anti-Aging Medicine and Longevity, 2016)
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Time and dose dependent effects of oxidative stress induced by cumene hydroperoxide in neuronal excitability of rat motor cortex neurons

Pardillo Díaz, Ricardo; Carrascal Moreno, María Livia; Muñoz Pinto, Mario Faustino; Ayala Gómez, Antonio; Núñez Abades, Pedro Antonio (Elsevier, 2016)
It has been claimed that oxidative stress and the production of reactive oxygen radicals can contribute to neuron degeneration ...
PhD Thesis
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Estudio de la viabilidad y diferenciación de las células madre mesenquimales de tejido adiposo en condiciones de estrés oxidativo y envejecimiento. Posibilidad de su uso terapéutico e influencia del factor de elongación 2

Muñoz Pinto, Mario Faustino; Ayala Gómez, Antonio; Guzmán Chozas, Matías; Guillen Sans, Remedios (2016)
The present thesis is a compilation of several experiments about the use of adiposederived mesenchymal stem cells (ADSCs) ...
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Chronic Stress Alters the Expression Levels of Longevity-related Genes in the Rat Hippocampus

Sánchez Hidalgo, Ana C.; Muñoz Pinto, Mario Faustino; Herrera Carmona, Antonio José; Espinosa Oliva, Ana María; Stowell, Rianne; Ayala Gómez, Antonio; Machado, Alberto; Venero Recio, José Luis; Martínez de Pablos, Rocío (Elsevier, 2016)
The molecular mechanisms underlying the negative effects of psychological stress on cellular stress during aging and ...
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Treatment with mesenchymal stem cells in an animal model of parkinson´s disease

Naranjo, José Ángel; Ayala Gómez, Antonio; Cano Rodríguez, María Mercedes; Argüelles Castilla, Sandro; Ruiz, Victoria; Muñoz Pinto, Mario Faustino (Federation of Anti-Aging Medicine Societies, 2015)
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Chronic stress enhances microglia activation and exacerbates death of nigral dopaminergic neurons under conditions of inflammation

Martínez de Pablos, Rocío; Herrera Carmona, Antonio José; Espinosa Oliva, Ana María; Sarmiento Soto, Manuel; Muñoz Pinto, Mario Faustino; Machado Quintana, Alberto; Venero Recio, José Luis (BioMed Central, 2014)
Background: Parkinson’s disease is an irreversible neurodegenerative disease linked to progressive movement disorders and ...
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Lipid peroxidation: Production, metabolism, and signaling mechanisms of malondialdehyde and 4-hydroxy-2-nonenal

Ayala Gómez, Antonio; Muñoz Pinto, Mario Faustino; Argüelles Castilla, Sandro (Hindawi Publishing Corporation, 2014)
Lipid peroxidation can be described generally as a process under which oxidants such as free radicals attack lipids ...
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Folic acid supplementation: some practical aspects

Cano Rodríguez, María Mercedes; Muñoz Pinto, Mario Faustino; Ayala Gómez, Antonio; Argüelles Castilla, Sandro (Federation of Anti-Aging Medicine Societies, 2012)
Since 1956, when Harman first postulated the free radical theory of aging, numerous studies have been carried out to test ...
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In vitro and in Vivo Protection by Melatonin Against the Decline of Elongation Factor-2 Caused by Lipid Peroxidation: Preservation of Protein Synthesis

Argüelles Castilla, Sandro; Muñoz Pinto, Mario Faustino; Cano Rodríguez, María Mercedes; Machado Quintana, Alberto; Ayala Gómez, Antonio (Wiley-Blackwell, 2012)
As organisms age, a considerable decrease in protein synthesis takes place in all tissues. Among the possible causes of ...
Chapter of Book
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Assessment of the General Oxidant Status of Individuals in Non-Invasive Samples

Argüelles Castilla, Sandro; Cano Rodríguez, María Mercedes; Muñoz Pinto, Mario Faustino; Ayala, Rafael; Ismaiel, Afrah; Ayala Gómez, Antonio (IntechOpen, 2012)
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Potential use of adipose tissue stem cells in the control of aging

Muñoz Pinto, Mario Faustino; Zurita Díaz, Francisco; Argüelles Castilla, Sandro; Vázquez, Rocío; Serres, José; Guzmán Chozas, Matías; Guillén Sanz, Remedios; Rodríguez Gómez, José Antonio; Cortés, José Luis; Muñoz Franco, Jaime; Pintor Toro, José Antonio; Cano Rodríguez, María Mercedes; Ayala Gómez, Antonio (Federation of Anti-Aging Medicine Societies, 2012)
Cell therapy with adult stem cells is a new battle front for the control of aging. Before being used for this purpose, we ...