Perfil del autor: Pernia Leal, Manuel
Datos institucionales
| Nombre | Pernia Leal, Manuel |
| Departamento | Química Orgánica y Farmaceútica |
| Área de conocimiento | Química Orgánica |
| Categoría profesional | Profesor Titular de Universidad |
| Correo electrónico | Solicitar |
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Estadísticas
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Nº publicaciones
21
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Nº visitas
2467
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Nº descargas
2692
| Publicaciones |
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Artículo
 Biological Evaluation of Carbohydrate-based Aprepitant Analogs for Neuroblastoma Treatment
(Elsevier, 2024)
Different studies using Aprepitant, a NK1R antagonist currently used as a clinical drug for treating chemotherapy-related ... |
Tesis Doctoral
Derivados de d-Galactosa como antagonistas de los receptores NK1 de interés terapéutico: aproximaciones al diseño de nuevos nanosistemas teranósticos
(2023)
A pesar de los enormes esfuerzos tanto económicos como científicos invertidos en la lucha contra el cáncer, éste sigue ... |
Artículo
Deciphering the Parameters to Produce Highly Reproducible and Scalable Iron Oxide Nanoparticles
(Royal Society of Chemistry, 2023)
Nanomedicine has been long hailed as a game changer for treating several ailments, but its translation from bench to bedside ... |
Artículo
Scaling Up Magnetic Nanobead Synthesis with Improved Stability for Biomedical Applications
(American Chemical Society, 2022)
The growing interest in multifunctional nano-objects based on polymers and magnetic nanoparticles for biomedical applications ... |
Artículo
Biologically Relevant Micellar Nanocarrier Systems for Drug Encapsulation and Functionalization of Metallic Nanoparticles
(MDPI, 2022)
The preparation of new and functional nanostructures has received more attention in the scientific community in the past ... |
Artículo
Passive targeting of high-grade gliomas via the EPR effect: a closed path for metallic nanoparticles?
(Royal Society of Chemistry, 2021)
Passive tumor targeting via the enhanced permeability and retention (EPR) effect has long been considered the most effective ... |
Artículo
 Fe₃ O₄-Au Core-Shell Nanoparticles as a Multimodal Platform for in Vivo Imaging and Focused Photothermal Therapy
(MDPI, 2021)
In this study, we report the synthesis of gold-coated iron oxide nanoparticles capped with polyvinylpyrrolidone (Fe@Au ... |
Trabajo Fin de Grado
Nanomedicinas para el diagnóstico y tratamiento del glioblastoma
(2021)
El glioblastoma es considerado el tumor primario cerebral más frecuente y agresivo en adultos, siendo 15 meses la ... |
Artículo
PEGylated Terbium-Based Nanorods as Multimodal Bioimaging Contrast Agents
(American Chemical Society, 2021)
Diagnostic imaging strongly relies on the use of contrast agents (CAs). In general terms, current CAs present undesirable ... |
Artículo
Carbohydrate-Based NK1R Antagonists with Broad-Spectrum Anticancer Activity
(American Chemical Society, 2021)
NK1R antagonists, investigated for the treatment of several pathologies, have shown encouraging results in the treatment ... |
Artículo
Clickable iron oxide NPs based on catechol derived ligands: synthesis and characterization
(Taylor and Francis Group, 2020)
Clickable magnetic nanoparticles have attracted great attention as potential nanoplatforms for biomedical applications ... |
Artículo
Bi-Magnetic Core-Shell CoFe2O4@MnFe2O4 Nanoparticles for In Vivo Theranostics
(MDPI, 2020)
In this work, we report the synthesis and characterization of three magnetic nanosystems, CoFe2O4, CoFe2O4@ZnFe2O4, and ... |
Artículo
Magnetic Nanoparticles as MRI Contrast Agents
(Springer, 2020)
Iron oxide nanoparticles (IONPs) have emerged as a promising alternative to conventional contrast agents (CAs) for magnetic ... |
Artículo
Comprehensive Toxicity Assessment of PEGylated Magnetic Nanoparticles for in vivo applications
(Elsevier, 2019)
Magnetic nanoparticles (MNPs) represent one of the greatest promises for the development of a new generation of diagnostic ... |
Artículo
Synthesis and Characterization of Elongated-Shaped Silver Nanoparticles as a Biocompatible Anisotropic SERS Probe for Intracellular Imaging: Theoretical Modeling and Experimental Verification
(MDPI, 2019)
Progress in the field of biocompatible SERS nanoparticles has promising prospects for biomedical applications. In this ... |
Artículo
Multifunctional Magnetic and Upconverting Nanobeads as Dual Modal Imaging Tools
(American Chemical Society, 2017)
We report the fabrication of aqueous multimodal imaging nanocomposites based on superparamagnetic nanoparticles (MNPs) and ... |
Artículo
Highly water-stable rare ternary Ag-Au-Se nanocomposites as long blood circulation time X-ray computed tomography contrast agents
(Royal Society of Chemistry, 2017)
X-ray computed tomography (CT) is a powerful and widely used medical non-invasive technique that often requires intravenous ... |
Artículo
Synthesis of 1D-glyconanomaterials by a hybrid noncovalent–covalent functionalization of single wall carbon nanotubes: a study of their selective interactions with lectins and with live cells
(Royal Society of Chemistry, 2015)
To take full advantage of the remarkable applications of carbon nanotubes in different fields, there is a need to develop ... |
Artículo
Improved non-covalent biofunctionalization of multi-walled carbon nanotubes using carbohydrate amphiphiles with a butterfly-like polyaromatic tail
(Springer, 2010)
We have developed an efficient strategy for the non-covalent functionalization of multi-walled carbon nanotubes (MWCNTs) ... |
Patente
Neoglicolipidos, sus agregados con nanotubos de carbono, procedimiento de obtencion y aplicaciones
(Oficina Española de Patentes y Marcas , 2009)
La presente invención se refiere a un glicolípido de fórmula (I) en la que R es un carbohidrato seleccionado entre un ... |
Artículo
Tailoring carbon nanotube surfaces with glyconanorings: New bionanomaterials with specific lectin affinity
(Royal Society of Chemistry, 2009)
Remarkably stable, water-soluble glyconanoring-coated SWCNTs were prepared by self organization and photopolymerization ... |