Author profile: Escudero Cuadrado, Luis María
Data
Name | Escudero Cuadrado, Luis María |
Department | Biología Celular |
Knowledge area | Biología Celular |
Professional category | Profesor Titular de Universidad |
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27
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3661
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Publications |
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Article
![]() The complex three-dimensional organization of epithelial tissues
(The Company of Biologists Ltd., 2021-01-01)
Understanding the cellular organization of tissues is key to developmental biology. In order to deal with this complex ... |
Article
![]() Mechanics and self-organization in tissue development
(Elsevier, 2021-01-01)
Self-organization is an all-important feature of living systems that provides the means to achieve specialization and ... |
PhD Thesis
![]() Topological analysis of the tumour microenvironment to study Neuroblastoma
(2020-09-03)
Solid tumours and their tumour microenvironment (TME) can be considered as complex networks whose elements are in constant ... |
PhD Thesis
![]() Scutoids unveil the three-dimensional packing in curved epithelia
(2020-07-16)
As animals develop, the initial simple planar epithelia of the early embryos must acquire complex three-dimensional ... |
Article
![]() EpiGraph: an open-source platform to quantify epithelial organization
(Oxford University Press, 2020-01-01)
Here we present EpiGraph, an image analysis tool that quantifies epithelial organization. Our method combines computational ... |
Article
![]() A quantitative principle to understand 3D cellular connectivity in epithelial tubes
(BioRxiv, 2020-01-01)
Apico-basal cell intercalations (scutoids) optimize packing and energy expenditure in curved epithelia. Further consequences ... |
Article
![]() The topology of vitronectin: A complementary feature for neuroblastoma risk classification based on computer-aided detection
(Wiley, 2020-01-01)
Tumors are complex networks of constantly interacting elements: tumor cells, stromal cells, immune and stem cells, ... |
Presentation
![]() Characterising epithelial tissues using persistent entropy
(Springer, 2019-01-01)
In this paper, we apply persistent entropy, a novel topological statis- tic, for characterization of images of epithelial ... |
Article
![]() Persistent entropy: a scale-invariant topological statistic for analyzing cell arrangements
(Cornell University, 2019-01-01)
In this work, we develop a method for detecting differences in the topological distribution of cells forming epithelial ... |
PhD Thesis |
Article
![]() Author Correction: Scutoids are a geometrical solution to three-dimensional packing of epithelia
(Nature Research, 2018-01-01)
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Article
![]() Scutoids are a geometrical solution to three-dimensional packing of epithelia
(Nature Publishing Group, 2018-01-01)
As animals develop, tissue bending contributes to shape the organs into complex three-dimensional structures. However, the ... |
Article
![]() Nintedanib decreases muscle fibrosis and improves muscle function in a murine model of dystrophinopathy
(Nature Publishing Group, 2018-01-01)
Duchenne muscle dystrophy (DMD) is a genetic disorder characterized by progressive skeletal muscle weakness. Dystrophin ... |
Article
![]() Rules of tissue packing involving different cell types: human muscle organization
(Nature Publishing Group, 2017-01-01)
Natural packed tissues are assembled as tessellations of polygonal cells. These include skeletal muscles and epithelial ... |
Article
![]() X-ray emission from a liquid curtain jet when irradiated by femtosecond laser pulses
(Springer Nature, 2017-01-01)
Laser-based sources of ionizing radiation have attracted considerable attention in the last years for their broad potential ... |
Article
![]() Fundamental physical cellular constraints drive self-organization of tissues
(Wiley-Blackwell, 2016-01-01)
Morphogenesis is driven by small cell shape changes that modulate tissue organization. Apical surfaces of proliferating ... |
PhD Thesis |
Article
![]() ATM specifically mediates repair of double-strand breaks with blocked DNA ends
(Nature Publishing Group, 2014-01-01)
Ataxia telangiectasia is caused by mutations in ATM and represents a paradigm for cancer predisposition and neurodegenerative ... |
Article
![]() Biotensegrity of the Extracellular Matrix: Physiology, Dynamic Mechanical Balance, and Implications in Oncology and Mechanotherapy
(Frontiers Media, 2014-01-01)
Cells have the capacity to convert mechanical stimuli into chemical changes. This process is based on the tensegrity ... |
Article
![]() Topological Progression in Proliferating Epithelia Is Driven by a Unique Variation in Polygon Distribution
(Public Library of Science, 2013-01-01)
Morphogenesis is consequence of lots of small coordinated variations that occur during development. In proliferating stages, ... |
Article
![]() Neuromuscular disease classification system
(Spie-soc photo-optical instrumentation engineers, 2013-01-01)
Diagnosis of neuromuscular diseases is based on subjective visual assessment of biopsies from patients by the pathologist ... |
Article
![]() Dual role of myosin II during Drosophila imaginal disc metamorphosis
(Nature Publishing Group, 2013-01-01)
The motor protein non-muscle myosin II is a major driver of the movements that sculpt three dimensional organs from two ... |
Article
![]() Age-mediated transcriptomic changes in adult mouse substantia nigra
(2013-01-01)
Substantia nigra pars compacta (SNpc) is highly sensitive to normal aging and selectively degenerates in Parkinson’s disease ... |
Article |
Article
![]() Epithelial organisation revealed by a network of cellular contacts
(Nature Publishing Group, 2011-01-01)
The emergence of differences in the arrangement of cells is the first step towards the establishment of many organs. ... |
Article
![]() Live imaging of Drosophila imaginal disc development
(National Academy of Sciences, 2010-01-01)
Live imaging has revolutionized the analysis of developmental biology over the last few years. The ability to track in ... |
Article
![]() Mechanism of G1 arrest in the Drosophila eye imaginal disc
(2007-01-01)
Background: Most differentiating cells are arrested in G1-phase of the cell cycle and this proliferative quiescence appears ... |