Data

NameEscudero Cuadrado, Luis María
DepartmentBiología Celular
Knowledge areaBiología Celular
Professional categoryProfesor Titular de Universidad
E-mailRequest
         

  Statistics

  • Items

    22

  • Visits

    2873

  • Downloads

    2859

  Publications

 

PhD Thesis
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Topological analysis of the tumour microenvironment to study Neuroblastoma

Escudero Cuadrado, Luis María; Vicente Munuera, Pablo (2020-09-03)
Solid tumours and their tumour microenvironment (TME) can be considered as complex networks whose elements are in constant ...
PhD Thesis
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Scutoids unveil the three-dimensional packing in curved epithelia

Escudero Cuadrado, Luis María; Gómez Gálvez, Pedro (2020-07-16)
As animals develop, the initial simple planar epithelia of the early embryos must acquire complex three-dimensional ...
Article
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EpiGraph: an open-source platform to quantify epithelial organization

Vicente Munuera, Pablo; Gómez Gálvez, Pedro; Tetley, Robert J.; Forja Barbosa, Cristina; Tagua Jáñez, Antonio Jesús; Letrán, Marta; Tozluoglu, Melda; Mao, Yanlan; Escudero Cuadrado, Luis María (Oxford University Press, 2020-01-01)
Here we present EpiGraph, an image analysis tool that quantifies epithelial organization. Our method combines computational ...
Article
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A quantitative principle to understand 3D cellular connectivity in epithelial tubes

Gómez Gálvez, Pedro; Vicente Munuera, Pablo; Anbari, Samira; Tagua Jáñez, Antonio; Gordillo Vázquez, Carmen María; Palacios, Ana M.; Velasco, Antonio; Capitán Agudo, Carlos; Grima Ruiz, Clara Isabel; Robles Arias, Rafael; Márquez Pérez, Alberto; Buceta, Javier; Escudero Cuadrado, Luis María (BioRxiv, 2020-01-01)
Apico-basal cell intercalations (scutoids) optimize packing and energy expenditure in curved epithelia. Further consequences ...
Presentation
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Characterising epithelial tissues using persistent entropy

Atienza Martínez, María Nieves; Escudero Cuadrado, Luis María; Jiménez Rodríguez, María José; Soriano Trigueros, Manuel (Springer, 2019-01-01)
In this paper, we apply persistent entropy, a novel topological statis- tic, for characterization of images of epithelial ...
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Persistent entropy: a scale-invariant topological statistic for analyzing cell arrangements

Atienza Martínez, María Nieves; Escudero Cuadrado, Luis María; Jiménez Rodríguez, María José; Soriano Trigueros, Manuel (Cornell University, 2019-01-01)
In this work, we develop a method for detecting differences in the topological distribution of cells forming epithelial ...
PhD Thesis
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Hypoxia and alzheimer's disease: the processing of amyloid precursor protein and the role of prolyl-hydroxylase 3 in microglia.

Pascual Bravo, Alberto; Escudero Cuadrado, Luis María; Sánchez García, Manuel A. (2018-10-01)
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Author Correction: Scutoids are a geometrical solution to three-dimensional packing of epithelia

Gómez Gálvez, Pedro; Vicente Munuera, Pablo; Tagua Jáñez, Antonio Jesús; Forja, Cristina; Castro Rodríguez, Ana María; Grima Ruiz, Clara Isabel; Bermúdez Gallardo, Marina; Márquez Pérez, Alberto; Escudero Cuadrado, Luis María (Nature Research, 2018-01-01)
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Scutoids are a geometrical solution to three-dimensional packing of epithelia

; Gómez Gálvez, Pedro; Vicente Munuera, Pablo; Tagua Jáñez, Antonio; Forja Barbosa, Cristina; Castro Rodríguez, Ana María; Letrán, Marta; Grima Ruiz, Clara Isabel; Bermúdez Gallardo, Marina; Serrano Pérez-Higueras, Óscar; Márquez Pérez, Alberto; Escudero Cuadrado, Luis María (Nature Publishing Group, 2018-01-01)
As animals develop, tissue bending contributes to shape the organs into complex three-dimensional structures. However, the ...
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Nintedanib decreases muscle fibrosis and improves muscle function in a murine model of dystrophinopathy

Piñol Jurado, Patricia; Suárez Calvet, Xavier; Fernández Simón, Esther; Gallardo, Eduard; Gómez Gálvez, Pedro; Escudero Cuadrado, Luis María; Díaz Manera, Jordi (Nature Publishing Group, 2018-01-01)
Duchenne muscle dystrophy (DMD) is a genetic disorder characterized by progressive skeletal muscle weakness. Dystrophin ...
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Rules of tissue packing involving different cell types: human muscle organization

Sánchez Gutiérrez, Daniel; Sáez Manzano, Aurora; Gómez Gálvez, Pedro; Paradas López, Carmen ‎; Escudero Cuadrado, Luis María (Nature Publishing Group, 2017-01-01)
Natural packed tissues are assembled as tessellations of polygonal cells. These include skeletal muscles and epithelial ...
PhD Thesis
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Estudio de la organización compleja de tejidos biológicos usando conceptos matemáticos

Escudero Cuadrado, Luis María; Muñiz Guinea, Manuel; Sánchez Gutiérrez, Daniel (2015-12-17)
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ATM specifically mediates repair of double-strand breaks with blocked DNA ends

Álvarez Quilón, Alejandro; Serrano Benítez, Almudena; Ariel Lieberman, Jenna; Quintero Ruiz, Maria Cristina; Sánchez Gutiérrez, Daniel; Escudero Cuadrado, Luis María; Cortés Ledesma, Felipe (Nature Publishing Group, 2014-01-01)
Ataxia telangiectasia is caused by mutations in ATM and represents a paradigm for cancer predisposition and neurodegenerative ...
Article
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Biotensegrity of the Extracellular Matrix: Physiology, Dynamic Mechanical Balance, and Implications in Oncology and Mechanotherapy

Tadeo Cervera, Irene; Berbegall, Ana Pilar; Escudero Cuadrado, Luis María; Álvaro Naranjo, Tomás; Noguera Salva, Rosa (Frontiers Media, 2014-01-01)
Cells have the capacity to convert mechanical stimuli into chemical changes. This process is based on the tensegrity ...
Article
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Topological Progression in Proliferating Epithelia Is Driven by a Unique Variation in Polygon Distribution

Sánchez Gutiérrez, Daniel; Sáez Manzano, Aurora; Pascual Bravo, Alberto; Escudero Cuadrado, Luis María (Public Library of Science, 2013-01-01)
Morphogenesis is consequence of lots of small coordinated variations that occur during development. In proliferating stages, ...
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Neuromuscular disease classification system

Sáez Manzano, Aurora; Acha Piñero, Begoña; Montero, Sánchez, Adoración; Rivas, Eloy; Escudero Cuadrado, Luis María; Serrano Gotarredona, María del Carmen (Spie-soc photo-optical instrumentation engineers, 2013-01-01)
Diagnosis of neuromuscular diseases is based on subjective visual assessment of biopsies from patients by the pathologist ...
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Dual role of myosin II during Drosophila imaginal disc metamorphosis

Aldaz, Silvia; Escudero Cuadrado, Luis María; Freeman, Matthew (Nature Publishing Group, 2013-01-01)
The motor protein non-muscle myosin II is a major driver of the movements that sculpt three dimensional organs from two ...
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Age-mediated transcriptomic changes in adult mouse substantia nigra

Gao Chen, Lin; Hidalgo-Figueroa, María; Escudero Cuadrado, Luis María; Díaz Martín, Juan; López Barneo, José; Pascual Bravo, Alberto (2013-01-01)
Substantia nigra pars compacta (SNpc) is highly sensitive to normal aging and selectively degenerates in Parkinson’s disease ...
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Quantifiable diagnosis of neuromuscular diseases through network analysis

Serrano Gotarredona, María del Carmen; Acha Piñero, Begoña; Rivas, Eloy; Escudero Cuadrado, Luis María; Sáez Manzano, Aurora; Montero Sánchez, Adoración; Paradas, Carmen; Pascual Bravo, Alberto (2013-01-01)
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Epithelial organisation revealed by a network of cellular contacts

Escudero Cuadrado, Luis María; Luciano da Fontoura Costa; Kicheva, Anna; Briscoe, James; Freeman, Matthew; Babu, M. Madan (Nature Publishing Group, 2011-01-01)
The emergence of differences in the arrangement of cells is the first step towards the establishment of many organs. ...
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Live imaging of Drosophila imaginal disc development

Aldaz, Silvia; Escudero Cuadrado, Luis María; Freeman, Matthew (National Academy of Sciences, 2010-01-01)
Live imaging has revolutionized the analysis of developmental biology over the last few years. The ability to track in ...
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Mechanism of G1 arrest in the Drosophila eye imaginal disc

Escudero Cuadrado, Luis María; Freeman, Matthew (2007-01-01)
Background: Most differentiating cells are arrested in G1-phase of the cell cycle and this proliferative quiescence appears ...