NameSanz Herrera, José Antonio
DepartmentMecánica de Medios Continuos y Teoría de Estructuras
Knowledge areaMecánica de Medios Continuos y Teoría de Estructuras
Professional categoryCatedrático de Universidad
E-mailRequest
           
  • No. publications

    36

  • No. visits

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A mechanobiological model for tumor spheroid evolution with application to glioblastoma: a continuum multiphysics approach

Carrasco Mantis, Ana; Randelovic, Teodora; Castro Abril, Héctor; Ochoa Garrido, Ignacio; Doblaré Castellano, Manuel; Sanz Herrera, José Antonio (Elsevier, 2023)
Background: Spheroids are in vitro quasi-spherical structures of cell aggregates, eventually cultured within a hydrogel ...
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Traction force reconstruction assessment on real three-dimensional matrices and cellular morphologies

Apolinar Fernández, Alejandro; Barrasa Fano, Jorge; Cóndor, M.; Van Oosterwyck, Hans; Sanz Herrera, José Antonio (Elsevier, 2023)
Traction force microscopy (TFM) allows to estimate tractions on the surface of cells when they mechanically interact with ...
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An in silico study on the influence of extracellular matrix mechanics on vasculogenesis

Carrasco Mantis, Ana; Alarcón, T.; Sanz Herrera, José Antonio (Elsevier, 2023)
Background and objectives: Blood vessels form a network of capillaries throughout the body that perform essential functions ...
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A mechanobiological model for tumor spheroid evolution with application to glioblastoma: A continuum multiphysics approach

Carrasco Mantis, Ana; Randelovic, Teodora; Castro Abril, Héctor; Ochoa Garrido, Ignacio; Doblaré Castellano, Manuel; Sanz Herrera, José Antonio (Elsevier, 2023)
Background: Spheroids are in vitro quasi-spherical structures of cell aggregates, eventually cultured within a hydrogel ...
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Time-Dependent Collagen Fibered Structure in the Early Distraction Callus: Imaging Characterization and Mathematical Modeling

Blázquez Carmona, Pablo; Sanz Herrera, José Antonio; Mora Macías, Juan; Morgaz, Juan; Domínguez Abascal, Jaime; Reina Romo, Esther (Biomedical Engineering Society, 2022)
Collagen is a ubiquitous protein present in regenerating bone tissues that experiences multiple biological phenomena during ...
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Understanding glioblastoma invasion using physically-guided neural networks with internal variables

Ayensa Jiménez, Jacobo; Doweidar, Mohamed Hamdy; Sanz Herrera, José Antonio; Doblare, M. (Public Library Science, 2022)
Microfluidic capacities for both recreating and monitoring cell cultures have opened the door to the use of Data Science ...
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Inverse method based on 3D nonlinear physically constrained minimisation in the framework of traction force microscopy

Sanz Herrera, José Antonio; Barrasa Fano, Jorge; Cóndor, M.; Van Oosterwyck, Hans (Royal Society of Chemistry, 2021)
Traction force microscopy is a methodology that enables to estimate cellular forces from the measurement of the displacement ...
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TFMLAB: A MATLAB toolbox for 4D traction force microscopy

Barrasa Fano, Jorge; Shapeti, Apeksha; Jorge Peñas, Álvaro; Barzegari, Mojtaba; Sanz Herrera, José Antonio; Van Oosterwyck, Hans (Elsevier B.V, 2021)
We present TFMLAB, a MATLAB software package for 4D (x;y;z;t) Traction Force Microscopy (TFM). While various TFM computational ...
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Advanced in silico validation framework for three-dimensional Traction Force Microscopy and application to an in vitro model of sprouting angiogenesis

Barrasa Fano, Jorge; Shapeti, Apeksha; de Jong, J.; Ranga, A.; Sanz Herrera, José Antonio; Van Oosterwyck, Hans (Elsevier, 2021)
In the last decade, cellular forces in three-dimensional hydrogels that mimic the extracellular matrix have been calculated ...
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Structural optimization of 3D-printed patient-specific ceramic scaffolds for in vivo bone regeneration in load-bearing defects

Blázquez Carmona, Pablo; Sanz Herrera, José Antonio; Martínez Vázquez, Francisco Javier; Domínguez, Jaime; Reina Romo, Esther (Elsevier Ltd, 2021)
Tissue engineering has recently gained popularity as an alternative to autografts to stimulate bone tissue regeneration ...
Master's Final Project
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Análisis cinemático de un modelo 3D de migración celular

Cañada Pérez, Celia; Sanz Herrera, José Antonio; Pérez Alcántara, Pedro (2021)
En el presente trabajo se ha realizado el análisis cinemático de movimientos en 3D de células individuales inmersas en un ...
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Analysis of the parametric correlation in mathematical modeling of In vitro glioblastoma evolution using copulas

Ayensa Jiménez, Jacobo; Pérez Aliacar, Marina; Randelovic, Teodora; Sanz Herrera, José Antonio; Doweidar, Mohamed Hamdy; Doblaré Castellano, Manuel (MDPI, 2021)
Modeling and simulation are essential tools for better understanding complex biological processes, such as cancer evolution. ...
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A multiscale data-driven approach for bone tissue biomechanics

Mora Macías, Juan; Ayensa Jiménez, Jacobo; Reina Romo, Esther; Doweidar, Mohamed Hamdy; Domínguez Abascal, Jaime; Doblaré, M.; Sanz Herrera, José Antonio (Elsevier, 2020)
The data-driven methodology with application to continuum mechanics relies upon two main pillars: (i) experimental ...
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Special Issue on “Biomaterials for Bone Tissue Engineering”

Sanz Herrera, José Antonio (MDPI, 2020)
The present Special Issue covers recent advances in the field of tissue engineering applied to bone tissue. Bone tissue ...
Master's Final Project
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Caracterización mecánica y modelización hiperelástica de hidrogeles de colágeno en aplicaciones de mecanobiología celular

Apolinar Fernández, Alejandro; Sanz Herrera, José Antonio (2020)
En la consecución de este trabajo se ha estudiado la viabilidad del empleo de tres modelos constitutivos hiperelásticos ...
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Mathematical formulation and parametric analysis of in vitro cell models in microfuidic devices: application to diferent stages of glioblastoma evolution

Ayensa Jiménez, Jacobo; Pérez-Aliacar, M.; Randelovic, T.; Oliván, S.; Fernández, L.; Sanz Herrera, José Antonio; Ochoa, I.; Doweidar, M.H. (Nature Research, 2020)
In silico models and computer simulation are invaluable tools to better understand complex biological processes such as ...
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Multiscale Characterisation of Cortical Bone Tissue

Sanz Herrera, José Antonio; Mora Macías, Juan; Reina Romo, Esther; Domínguez Abascal, Jaime; Doblaré, M. (MDPI, 2019)
Multiscale analysis has become an attractive technique to predict the behaviour of materials whose microstructure strongly ...
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Continuum Modeling and Simulation in Bone Tissue Engineering

Sanz Herrera, José Antonio; Reina Romo, Esther (MDPI, 2019)
Bone tissue engineering is currently a mature methodology from a research perspective. Moreover, modeling and simulation ...
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Numerical investigation of the coupled mechanical behavior of self-healing materials under cyclic loading

Sanz Herrera, José Antonio; Aliko Benítez, Abraham; Fadrique Contreras, A.M. (Elsevier, 2019)
Self-healing structural materials are recognized as a cost effective and sustainable promising alternative to traditional ...
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Computational Multiscale Solvers for Continuum Approaches

Montero Chacón, Francisco de Paula; Sanz Herrera, José Antonio; Doblaré, M. (MDPI, 2019)
Computational multiscale analyses are currently ubiquitous in science and technology. Different problems of interest-e.g., ...
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An unsupervised data completion method for physically-based data-driven models

Ayensa Jiménez, Jacobo; Doweidar, Mohamed Hamdy; Sanz Herrera, José Antonio; Doblaré, M. (Elsevier, 2019)
Data-driven methods are an innovative model-free approach for engineering and sciences, still in process of maturation. ...
Final Degree Project
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Implementación del modelo Concrete Damage Plasticity en el contexto del hormigón autorreparable

Gómez-Coronado Castillo, Pedro; Sanz Herrera, José Antonio; Montero Chacón, Francisco de Paula (2019)
En el presente documento se va a llevar a cabo un estudio en el ámbito de la mecánica de materiales y de los materiales ...
Master's Final Project
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Desarrollo de técnicas de mallado MEF avanzadas en Traction Force Microscopy 3D

Rojas Naranjo, Manuel; Sanz Herrera, José Antonio (2019)
En los últimos años, el hecho de que las fuerzas mecánicas juegan un papel central en la toma de decisiones celulares ha ...
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Model of dissolution in the framework of tissue engineering and drug delivery

Sanz Herrera, José Antonio; Soria Conde, Laureano; Reina Romo, Esther; Torres Hernández, Yadir; Boccaccini, Aldo R. (Springer, 2018)
Dissolution phenomena are ubiquitously present in biomaterials in many different fields. Despite the advantages of ...
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In silico dynamic characterization of the femur: Physiological versus mechanical boundary conditions

Reina Romo, Esther; Rodríguez Vallés, José; Sanz Herrera, José Antonio (Elsevier, 2018)
It is established that bone tissue adapts and responds to mechanical loading. Several studies have suggested an existence ...
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In silico design of magnesium implants: Macroscopic modelling

Sanz Herrera, José Antonio; Reina Romo, Esther; Boccaccini, Aldo R. (Elsevier, 2018)
Magnesium-based biomedical implants offer many advantages versus traditional ones although some challenges are still ...
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A new reliability-based data-driven approach for noisy experimental data with physical constraints

Ayensa Jiménez, Jacobo; Doweidar, Mohamed Hamdy; Sanz Herrera, José Antonio; Doblaré, M. (Elsevier, 2018)
Data Science has burst into simulation-based engineering sciences with an impressive impulse. However, data are never ...
PhD Thesis
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Modelo mecano-químico-difusivo fenomenológico de autorreparación: Implementación numérica y simulación con aplicación a materiales estructurales

Aliko Benítez, Abraham; Sanz Herrera, José Antonio (2017)
El concepto de material autorreparable, i.e. material que de forma autónoma tiene la capacidad de recuperar total o ...
Final Degree Project
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Simulación computacional de la deformabilidad del núcleo celular

Ballestero de Juan, Adolfo; Sanz Herrera, José Antonio (2017)
En este proyecto se persigue desarrollar un modelo computacional del núcleo de una célula cancerosa extraída de un ...
Master's Final Project
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Un modelo probabilístico para el cálculo estructural de sistemas mecánicos y la aplicación a la optimización de sistemas

Ayensa Jiménez, Jacobo; Sanz Herrera, José Antonio (2016)
La necesidad imperiosa por situar la ingeniería en un contexto de escasez obliga indirectamente cada vez más al ingeniero ...
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Cell-Biomaterial Mechanical Interaction in the Framework of Tissue Engineering: Insights, Computational Modeling and Perspectives

Sanz Herrera, José Antonio; Reina Romo, Esther (MDPI, 2011)
Tissue engineering is an emerging field of research which combines the use of cell-seeded biomaterials both in vitro and/or ...
Presentation
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Aplicación a la docencia en ingeniería de las estructuras de las nuevas metodologías adaptadas al plan de Bolonia

Sanz Herrera, José Antonio; Concha Martínez, Antonio de la; Ariza Moreno, María del Pilar; Tortosa Ybáñez, María Teresa; Álvarez Teruel, José Daniel; Pellín Buades, Neus (Universitat d´Alacant / Universidad de Alicante, Instituto de Ciencias de la Educación, 2011)
La adaptación de los nuevos planes de estudio al Plan de Bolonia es hoy día un hecho que se está materializando en la ...
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Fast multipole method applied to 3D frequency domain elastodynamics

Sanz Herrera, José Antonio; Bonnet, Marc; Domínguez Abascal, José (Elsevier, 2008)
This article is concerned with the formulation and implementation of a fast multipole- accelerated BEM for 3-D elastodynamics ...
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Solución numérica para fractura en sólidos piezoeléctricos tridimensionales

Solís Muñiz, Mario; Sanz Herrera, José Antonio; Domínguez Abascal, José (Grupo español de fractura, 2007)
En este trabajo se presenta una formulación mixta del Método de los Elementos de Contorno (MEC) para el análisis de problemas ...
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Hypersingular BEM for Piezoelectric Solids: Formulation and Applications for FractureMechanics

Sanz Herrera, José Antonio; Solís Muñiz, Mario; Domínguez Abascal, José (Tech Science Press, 2007)
A general mixed boundary element formulation for three-dimensional piezoelectric fracture mechanics problems is presented ...
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El método de los elementos de contorno aplicado a mecánica de la fractura en sólidos piezoeléctricos

Sanz Herrera, José Antonio; Solís Muñiz, Mario; Ariza Moreno, María del Pilar (Grupo español de fractura, 2006)
A classical BE approach for 3D anisotropic piezoelectric fracture mechanics problems is presented in this paper. ...