Author profile: Pozo Pérez, David
Institutional data
Name | Pozo Pérez, David |
Department | Bioquímica Médica y Biología Molecular e Inmunología |
Knowledge area | Bioquímica y Biología Molecular |
Professional category | Profesor Titular de Universidad |
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Statistics
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No. publications
28
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No. visits
4088
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No. downloads
5360
Publications |
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PhD Thesis
Mecanismos modulatorios de MOK en la regulación de la respuesta inflamatoria de la microglía en ELA
(2024)
La esclerosis lateral amiotrófica (ELA) es una enfermedad neurodegenerativa actualmente incurable que, en el momento del ... |
Article
VEGF expression disparities in brainstem motor neurons of the SOD1GP3A ALS model: Correlations with neuronal vulnerability
(Elsevier, 2024)
Amyotrophic lateral sclerosis (ALS) is a rare neuromuscular disease characterized by severe muscle weakness mainly due to ... |
Article
Editorial: SARS-CoV-2 in neurodegenerative diseases
(Frontiers Media S.A., 2024)
In the month of March in the year 2020, an alarming pandemic triggered by the SARS CoV-2 virus, which leads to the development ... |
Article
MAPK/MAK/MRK overlapping kinase (MOK) controls microglial inflammatory/type- I IFN responses via Brd4 and is involved in ALS
(National Academy of Sciences, 2023)
Amyotrophic lateral sclerosis (ALS) is a fatal and incurable neurodegenerative disease affecting motor neurons and ... |
Article
Editorial: Nanoparticle-Mediated Signaling Rewiring and Reprogramming of Immune Responses
(FRONTIERS MEDIA SA, 2022)
Recent advances on the molecular mechanisms that control immune cells are at the core of the development of better ... |
Article
Titanium Surface Characteristics Induce the Specific Reprogramming of Toll-like Receptor Signaling in Macrophages
(MDPI, 2022)
Most of the research on titanium-based dental implants (Ti-discs) is focused on how they are able to stimulate the formation ... |
Article
Distinct responses of human peripheral blood cells to different misfolded protein oligomers
(Wiley-Blackwell, 2021)
Increasing evidence indicates that peripheral immune cells play a prominent role in neurodegeneration connected to protein ... |
Article
The metabesity factor HMG20A potentiates astrocyte survival and reactive astrogliosis preserving neuronal integrity
(IVYSPRING INT PUBL, 2021)
Rationale: We recently demonstrated that the ‘Metabesity’ factor HMG20A regulates islet beta-cell functional maturity and ... |
Article
Modified level of miR-376a is associated with Parkinson's disease
(Willey, 2020)
Parkinson's disease (PD) is a frequent progressive neurodegenerative disorder. Impaired mitochondrial function is a major ... |
PhD Thesis |
Article
Differential Interactome and Innate Immune Response Activation of Two Structurally Distinct Misfolded Protein Oligomers
(American Chemical Society, 2019)
The formation of misfolded protein oligomers during early stages of amyloid aggregation and the activation of neuroinflammatory ... |
Article
Immunization with α-synuclein/Grp94 reshapes peripheral immunity and suppresses microgliosis in a chronic parkinsonism model
(Wiley, 2018)
Neuroinflammation mediated by chronically activated microglia, largely caused by abnormal accumulation of misfolded ... |
Article
Adipose-derived mesenchymal stem cells (AdMSC) for the treatment of secondary-progressive multiple sclerosis: A triple blinded, placebo controlled, randomized phase I/II safety and feasibility study
(Public Library of Science, 2018)
Background Currently available treatments for secondary progressive multiple sclerosis(SPMS) have limited efficacy and/or ... |
PhD Thesis
Alpha-synuclein and immune system crosstalk in parkinson's disease; therapeutic approaches of its modulation by molecular chaperones
(2017)
This Doctoral Thesis is focused on the interplay between the immune system and the Parkinson’s related protein alpha-Synuclein. ... |
Patent. Invention
Biomarcadores para la esclerosis lateral amiotrófica (ELA)
(Organización Mundial de la Propiedad Intelectual (OMPI), 2017)
La presente invención está dirigida al uso de los gens/es MyD88y/o TL3 para el diagnóstico, pronóstico y/o seguimiento de ... |
PhD Thesis
Esclerosis lateral amiotrófica: investigaciones en el modelo sod1g93a y correlaciones de interés clínico
(2016)
La esclerosis lateral amiotrófica (ELA) es una enfermedad neurodegenerativa, incurable y de carácter fatal en un plazo de ... |
Patent. Invention
Combinaciones de proteínas agregantes y chaperonas moleculares para el tratamiento de proteinopatías o enfermedades conformacionales
(Organización Mundial de la Propiedad Intelectual (OMPI), 2015)
Las HSPs (chaperonas o proteínas de choque térmico ('heat-shock proteins' o HSPs)) poseen dos características muy valiosas ... |
PhD Thesis
Nanotechnology approaches for improvoved vasoactive intestinal peptide based-drug delivery systems
(2014)
The specific purpose of this project is to study the feasibility as a proof of concept of different nanotechnology approaches ... |
Article
Chaperoned amyloid proteins for immune manipulation: a-Synuclein/Hsp70 shifts immunity toward a modulatory phenotype
(Wiley Open Access, 2014)
α-Synuclein (αSyn) is a 140-residue amyloid-forming protein whose aggregation is linked to Parkinson's disease (PD). It ... |
Patent. Invention
Nanoliposomas funcionalizados con péptidos bioactivos como sistemas para mejorar la citotoxicidad de fármacos antitumorales
(Oficina Española de Patentes y Marcas (OEPM), 2013)
Nanoliposomas funcionalizados con péptidos en su superficie que permiten la identificación de tejidos y/o células diana y ... |
Patent. Invention
Nanoliposomas funcionalizados con péptidos bioactivos como sistemas para mejorar la citotoxicidad de fármacos antitumorales
(Oficina Española de Patentes y Marcas (OEPM), 2013)
La presente invención se relaciona con nanoliposomas funcionalizados con péptidos bioactivos en su superficie que permiten ... |
Patent. Invention
Utilización de nanopartículas de metales nobles como inmunomoduladores y composición inmunomoduladora
(Oficina Española de Patentes y Marcas (OEPM), 2011)
Utilización de nanopartículas de metales nobles como inmunomoduladores y composición inmunomoduladora. La presente invención ... |
Patent. Invention
Nanopartículas metálicas funcionalizadas con el neuropéptido VIP y procedimiento de preparación
(Oficina Española de Patentes y Marcas (OEPM), 2010)
Nanopartículas metálicas funcionarizadas con el neuro péptido VIP y procedimiento de preparación. Constituye el objeto de ... |
Article |
Patent. Invention
Uso de la melatonina como adyuvante
(Oficina Española de Patentes y Marcas (OEPM), 2008)
Uso de la melatonina como adyuvante. La presente invención se refiere al uso de la melatonina como adyuvante en preparados ... |
Article |
Article
Histomorphogenesis and immunohistochemical study of the bovine pineal gland (Bos taurus) during prenatal development (160 days of gestation to birth)
(Universidad de Murcia. Departamento de Biología Celular e Histología, 2006)
The ontogenesis of the pineal gland of 20 bovine embryos (Bos taurus) has been analysed from 160 days of gestation to birth ... |
Article
Vasoactive intestinal peptide induces regulatory dendritic cells with therapeutic effects on autoimmune disorders
(National Academy of Sciences, 2005)
The induction of antigen-specific tolerance is critical for the prevention of autoimmunity and maintenance of immune ... |