Author profile: Pardal Redondo, Ricardo
Institutional data
Name | Pardal Redondo, Ricardo |
Department | Fisiología Médica y Biofísica |
Knowledge area | Fisiología |
Professional category | Catedrático de Universidad |
Request | |
Statistics
-
No. publications
33
-
No. visits
5090
-
No. downloads
5456
Publications |
---|
PhD Thesis
Characterization of undifferentiated neuroblastoma cells and their contribution to aggressiveness
(2024)
Neuroblastoma (NB) represents the most prevalent extracranial solid tumor among children, originating from cells within ... |
Article
Protection and repair of the nigrostriatal pathway with stem-cell-derived carotid body glomus cell transplants in chronic MPTP Parkinsonian model
(MDPI, 2023)
Antiparkinsonian carotid body (CB) cell therapy has been proven to be effective in rodent and nonhuman primate models of ... |
Article
Rearrangement of cell types in the rat carotid body neurogenic niche induced by chronic intermittent hypoxia
(Wiley, 2023)
The carotid body (CB) is a prototypical acute oxygen (O2)-sensing organ that mediates reflex hyperventilation and increased ... |
Article
Analysis of serial neuroblastoma PDX passages in mice allows the identification of new mediators of neuroblastoma aggressiveness
(MDPI, 2023)
Neuroblastoma is a neural crest cell-derived pediatric tumor characterized by high interand intra-tumor heterogeneity, and ... |
PhD Thesis
Estudio de la familia de proteínas Rho GTPasas en la biología del neuroblastoma
(2022)
El neuroblastoma (NB) es el tumor extracraneal sólido de aparición más común durante la edad pediátrica. El NB surge a ... |
Article
A protocol to enrich in undifferentiated cells from neuroblastoma tumor tissue samples and cell lines
(Cell Press, 2022)
The existence of a subpopulation of undifferentiated cells with stem-like properties has been suggested in neuroblastoma ... |
Final Degree Project
Regulación de la fisiología de las células neuronales inmaduras en el cuerpo carotídeo.
(2022)
El cuerpo carotídeo es un órgano pequeño situado en la bifurcación de la arteria carótida. Su función principal es la de ... |
Article
Neurotransmitter Modulation of Carotid Body Germinal Niche
(MDPI AG, 2020)
The carotid body (CB), a neural-crest-derived organ and the main arterial chemoreceptor in mammals, is composed of clusters ... |
PhD Thesis
Papel de la quinasa humana VRK1 en la biología del neuroblastoma
(2020)
El neuroblastoma es el tumor extracraneal sólido más frecuente en la infancia. Su comportamiento es muy heterogéneo, ... |
Article |
Article
Identification of vrk1 as a new neuroblastoma tumor progression marker regulating cell proliferation
(Multidisciplinary Digital Publishing Institute (MDPI), 2020)
Neuroblastoma (NB) is one of the most common pediatric cancers and presents a poor survival rate in affected children. ... |
Article
Hypoxia in the Initiation and Progression of Neuroblastoma Tumours
(MDPI, 2020)
Neuroblastoma is the most frequent extracranial solid tumour in children, causing 10% of all paediatric oncology deaths. ... |
Article |
Chapter of Book
Progenitor Cell Heterogeneity in the Adult Carotid Body Germinal Niche
(Springer, 2019)
Somatic stem cells confer plasticity to adult tissues, permitting their maintenance, repair and adaptation to a changing ... |
Article
CD44-high neural crest stem-like cells are associated with tumour aggressiveness and poor survival in neuroblastoma tumours
(Elsevier, 2019)
BACKGROUND: Neuroblastoma is a paediatric tumour originated from sympathoadrenal precursors and characterized by its ... |
Article
The carotid body: a physiologically relevant germinal niche in the adult peripheral nervous system
(Springer, 2018)
Oxygen constitutes a vital element for the survival of every single cell in multicellular aerobic organisms like mammals. ... |
PhD Thesis
Mecanismos neurogénicos en respuesta a hipoxia en el cuerpo carotídeo. Presencia de neuronas inmaduras en el sistema nervioso periférico adulto
(2017)
El cuerpo carotídeo (CC) es un pequeño órgano localizado bilateralmente en la bifurcación de la arteria carótida, y cuya ... |
Article
Physiological Plasticity of Neural-Crest-Derived Stem Cells in the Adult Mammalian Carotid Body
(Cell Press, 2017)
Adult stem cell plasticity, or the ability of somatic stem cells to cross boundaries and differentiate into unrelated cell ... |
Article
Neural crest derived progenitor cells contribute to tumor stroma and aggressiveness in stage 4/M neuroblastoma
(Impact Journals, 2017)
Pediatric tumors arise upon oncogenic transformation of stem/progenitor cells during embryonic development. Given this ... |
Article
Gene expression profiling supports the neural crest origin of adult rodent carotid body stem cells and identifies CD10 as a marker for mesectoderm-committed progenitors
(WILEY, 2016)
Neural stem cells (NSCs) are promising tools for understanding nervous system plasticity and repair, but their use is ... |
Article
Carotid body oxygen sensing and adaptation to hipoxia
(Springer, 2015)
The carotid body (CB) is the principal arterial chemoreceptor that mediates the hyperventilatory response to hypoxia. Our ... |
PhD Thesis
Plasticidad fisiológica de las células madre del cuerpo carotídeo adulto: caracterización del linaje mesectodérmico
(2015)
El cuerpo carotídeo (CB), un órgano quimiosensor derivado de la cresta neural, permite la adaptación a la hipoxia crónica ... |
Article
Resistance of subventricular neural stem cells to chronic hypoxemia despite structural disorganization of the germinal center and impairment of neuronal and oligodendrocyte survival
(Dove Medical Press Ltd., 2015)
Chronic hypoxemia, as evidenced in de-acclimatized high-altitude residents or in patients with chronic obstructive respiratory ... |
PhD Thesis
Hipertrofia del cuerpo carotídeo en hipoxia crónica: mecanismos de activación, proliferación y diferenciación de los progenitores neurales en el sistema nervioso periférico
(2014)
The goal of this doctoral thesis is to achieve a better understanding of the biology and behavior of the recently discovered ... |
Article
An O-2-sensitive glomus cell-stem cell synapse induces carotid body growth in chronic hipoxia
(CELL PRESS, 2014)
Neural stem cells (NSCs) exist in germinal centers of the adult brain and in the carotid body (CB), an oxygen-sensing organ ... |
Chapter of Book
A pathophysiological view of the neural stem cell niche
(Nova Science Publishers, INC. U.S., 2011)
Neural stem cells were described in the nervous system some decades ago as being responsible for adult neurogenesis and ... |
Article
The carotid body, a neurogenic niche in the adult peripheral nervous system
(Univ pisa, 2010)
We have described a new population of adult neural stem cells residing in the carotid body, a chemoreceptor organ in the ... |
Article
Rotenone selectively occludes sensitivity to hypoxia in rat carotid body glomus cells
(Wiley-Blackwell Publishing Ltd., 2003)
Carotid body glomus cells release transmitters in response to hypoxia due to the increase of excitability resulting from ... |
Article
Trophic restoration of the nigrostriatal dopaminergic pathway in long-term carotid body-grafted parkinsonian rats
(2003)
We studied the mechanisms underlying long-term functional recovery of hemiparkinsonian rats grafted intrastriatally with ... |
PhD Thesis
Sensibilidad a hipoxia e hipoglucemia de células glómicas en rodajas de cuerpo carotídeo
(2000)
Los objetivos generales del presente trabajo fueron los siguientes: 1. Puesta a punto de la preparación de rodajas finas ... |
Article
Collapse of conductance Is prevented by a Glutamate residue conserved in voltage-dependent K+ channels
(2000)
Voltage-dependent K 1 channel gating is influenced by the permeating ions. Extracellular K 1 determines the occupation of ... |
Article
Secretory responses of intact glomus cells in thin slices of rat carotid body to hypoxia and tetraethylammonium
(2000)
We have developed a thin-slice preparation of whole rat carotid body that allows us to perform patch-clamp recording of ... |
Article |