Author profile: Muntané Relat, Jordi
Institutional data
| Name | Muntané Relat, Jordi |
| Department | Fisiología Médica y Biofísica |
| Knowledge area | Fisiología |
| Professional category | Profesor Titular de Universidad |
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Statistics
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No. publications
37
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No. visits
4615
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No. downloads
7063
| Publications |
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PhD Thesis
 Determinación de CTCs como marcador pronóstico en el cáncer de páncreas
(2023)
Introducción. El cáncer de páncreas es un tumor maligno intratable en el que la mayoría de los pacientes no muestran ... |
PhD Thesis
Molecular description of the role of protein synthesis in the cellular response to the treatment with the antitumoral drug Sorafenib in HCC lines
(2023)
El carcinoma hepatocellular (CHC) es reconocido como el principal cáncer primario de hígado y uno de los cánceres con mayor ... |
PhD Thesis
Regulation of miRNA expression during Sorafenib treatment in hepatocellular carcinoma. Development of a new therapeutic approach
(2023)
Hepatocellular carcinoma (HCC) is one of the most frequent neoplasias and one of the major causes of cancer-related death ... |
Article
Hepatocellular carcinoma risk-stratification based on ASGR1 in circulating epithelial cells for cancer interception
(Frontiers, 2022)
Purpose: Lack of diagnostic and prognostic biomarkers in hepatocellular carcinoma impedes stratifying patients based on ... |
Article
miR-200c-3p, miR-222-5p, and miR-512-3p Constitute a Biomarker Signature of Sorafenib Effectiveness in Advanced Hepatocellular Carcinoma
(MDPI, 2022)
Background: Sorafenib constitutes a suitable treatment alternative for patients with advanced hepatocellular carcinoma ... |
PhD Thesis
Hidrogeles supramoleculares y nanosistemas funcionales basados en carbohidratos para diferentes aplicaciones biomédicas
(2022)
Debido a la multitud de funciones que a día de hoy se conocen que desempeñan los carbohidratos dentro del entorno celular ... |
Article
The role of non-coding RNAs in autophagy during carcinogenesis
(Frontiers Media S.A., 2022)
Macroautophagy (autophagy herein) is a cellular stress response and a survival pathway involved in self-renewal and quality ... |
Article
 Broad Transcriptomic Impact of Sorafenib and Its Relation to the Antitumoral Properties in Liver Cancer Cells
(Multidisciplinary Digital Publishing Institute (MDPI), 2022)
Hepatocellular carcinoma (HCC) is one of the most frequent and essentially incurable cancers in its advanced stages. The ... |
Article
Impact of nitric oxide in liver cancer microenvironment
(Academic Press (Elsevier), 2022)
The pro- or antitumoral properties of nitric oxide (NO) are dependent on local concentration, redox state, cellular status, ... |
PhD Thesis
Síntesis y caracterización de nuevas formulaciones basadas en la incorporación de sorafenib en nanoestructuras funcionalizadas con manosa y galactosa para el tratamiento de células tumorales hepáticas
(2021)
El carcinoma hepatocelular (HCC) representa el 80% de las neoplasias hepáticas primarias que aparecen principalmente en ... |
Article
Role of nitric oxide in gene expression regulation during cancer: epigenetic modifications and non-coding RNAs
(MDPI, 2021)
Nitric oxide (NO) has been identified and described as a dual mediator in cancer according to dose-, time- and ... |
Article
Inhibition of the NLRP3 inflammasome prevents ovarian aging
(American Association for the Advancement of Science, 2021)
Inflammation is a hallmark of aging and is negatively affecting female fertility. In this study, we evaluate the role of ... |
Article
Integrated molecular signaling involving mitochondrial dysfunction and alteration of cell metabolism induced by tyrosine kinase inhibitors in cancer
(Elsevier, 2020)
Cancer cells have unlimited replicative potential, insensitivity to growth-inhibitory signals, evasion of apoptosis,cellular ... |
Article
Mitochondria and T2D: Role of Autophagy, ER Stress, and Inflammasome
(Cell Press, 2020)
Type 2 diabetes (T2D) is one of the main current threats to human health. Both T2D and its numerous clinical complications ... |
Article
Assessing Autophagy in Archived Tissue or How to Capture Autophagic Flux from a Tissue Snapshot
(MDPI, 2020)
Autophagy is a highly conserved degradation mechanism that is essential for maintaining cellular homeostasis. In human ... |
Article
Molecular Pathways Leading to Induction of Cell Death and Anti-Proliferative Properties by Tacrolimus and mTOR Inhibitors in Liver Cancer Cells
(1421-9778, 2020)
Background/Aims: Orthotopic liver transplantation (OLT) is the recommended treatment for patients at early stages of ... |
Article
Downregulation of thioredoxin-1-dependent CD95 S-nitrosation by Sorafenib reduces liver cáncer
(Elsevier, 2020)
Hepatocellular carcinoma (HCC) represents 80% of the primary hepatic neoplasms. It is the sixth most frequent neoplasm, ... |
Article
Differential effectiveness of tyrosine kinase inhibitors in 2D/3D culture according to cell differentiation, p53 status and mitochondrial respiration in liver cancer cells
(Springer Nature, 2020)
Sorafenib and Regorafenib are the recommended first- and second-line therapies in patients with advanced hepatocellular ... |
Article
Mechanisms of action of metformin in type 2 diabetes: Effects on mitochondria and leukocyte-endothelium interactions
(Elsevier, 2020)
Type 2 diabetes (T2D) is a very prevalent, multisystemic, chronic metabolic disorder closely related to atherosclerosis ... |
Article
Thioredoxin Downregulation Enhances Sorafenib Effects in Hepatocarcinoma Cells
(MDPI, 2019)
Sorafenib is the first-line recommended therapy for patients with advanced hepatocarcinoma (HCC) in de-differentiation ... |
Article
Nanostructured fibrin agarose hydrogel as a novel haemostatic agent
(Wiley, 2019)
Blood loss remains a major concern during surgery and can increase the morbidity of the intervention. The use of topical ... |
Article
Simvastatin and metformin inhibit cell growth in hepatitis C virus infected cells via mTOR increasing PTEN and autophagy
(2018)
Hepatitis C virus (HCV) infection has been related to increased risk of development of hepa tocellular carcinoma (HCC) ... |
PhD Thesis
Papel del p53 y los receptores de muerte celular en la supervivencia de paciente con hepatocarcinoma: implicación en el mecanismo antitumoral de Sorafenib
(2018)
Los receptores de proliferación tirosina quinasa y RAS están frecuentemente activados en el Hepatocarcinoma. Sorafenib fue ... |
PhD Thesis
Estudio histopatológico e inmunohistoquímico de xenoinjertos humanos de tumores periampulares.
(2017)
Los tumores periampulares y especialmente el adenocarcinoma de páncreas presentan en la actualidad una supervivencia a los ... |
PhD Thesis
Estudio de la viabilidad de los xenoinjertos de adenocarcinomas y tumores periampulares de páncreas
(2017)
Debido al mal pronóstico de los tumores del área periampular y especialmente de adenocarcinoma de páncreas (ADCP), resulta ... |
Article
NLRP3-inflammasome inhibition prevents high fat and high sugar diets-induced heart damage through autophagy induction
(Impact Journals LLC, 2017)
The NLRP3-inflammasome complex has emerged as an important component of inflammatory processes in metabolic dysfunction ... |
Article
NLRP3-inflammasome inhibition prevents high fat and high sugar diets-induced heart damage through autophagy induction
(Impact Journals, 2017)
The NLRP3-inflammasome complex has emerged as an important component of inflammatory processes in metabolic dysfunction ... |
Article
Differential Antitumoral Properties and Renal-Associated Tissue Damage Induced by Tacrolimus and Mammalian Target of Rapamycin Inhibitors in Hepatocarcinoma: In Vitro and In Vivo Studies
(2016)
Orthotopic liver transplantation (OLT) is the recommended treatment for patients at early stages of hepatocarcinoma (HCC) ... |
Article
Amitriptyline induces mitophagy that precedes apoptosis in human HepG2 cells
(2016)
Systemic treatments for hepatocellular carcinoma (HCC) have been largely unsuccessful. This study investigated the antitumoral ... |
PhD Thesis
Drenaje biliar interno versus anticuerpos anti-factor de necrosis tumoral -alfa sobre las alteraciones de la inmunidad celular en la ictericia obstructiva experimental
(2016)
Objetivos: Evaluar el efecto del drenaje biliar interno y los anticuerpos antiTNF-a en las alteraciones de la inmunidad ... |
Article
Oxidative stress influence on renal dysfunction in patients with obstructive jaundice: A case and control prospective study
(Elsevier, 2015)
Obstructive Jaundice (OJ) is associated with a significant risk of developing acute renal failure (ARF). The involvement ... |
Article
Regulation of cell death receptor S-nitrosylation and apoptotic signaling by Sorafenib in hepatoblastoma cells
(Elsevier, 2015)
Nitric oxide (NO) plays a relevant role during cell death regulation in tumor cells. The overexpression of nitric oxide ... |
Article
Obesity dependent metabolic signatures associated with nonalcoholic fatty liver disease progression
(2012)
Our understanding of the mechanisms by which nonalcoholic fatty liver disease (NAFLD) progresses from simple steatosis to ... |
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