Perfil del autor: Ayala Gómez, Antonio
Datos institucionales
| Nombre | Ayala Gómez, Antonio |
| Departamento | Bioquímica y Biología Molecular |
| Área de conocimiento | Bioquímica y Biología Molecular |
| Categoría profesional | Catedrático de Universidad |
| Correo electrónico | Solicitar |
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Estadísticas
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Nº publicaciones
42
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Nº visitas
8992
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Nº descargas
14366
| Publicaciones |
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Artículo
 Neutrophil-lymphocyte ratio and update conclusions from a 2-year double-blind rct testing fermented papaya preparation in healthy middle-aged/elderly subjects
(Functional Food Center, 2024)
Background:T his study represents the second part of a 2-year interventional study in middle-aged /elderly healthy subjects ... |
Artículo
The Emerging Role of Senotherapy in Cancer: A Comprehensive Review
(MDPI, 2023)
Senotherapy, a promising therapeutic strategy, has drawn a lot attention recently due to its potential for combating cancer. ... |
Artículo
Interim report from a 2-year double-blind RCT testing fermented papaya preparation on immune enhancement, endothelial health and QOL in elderly adults
(2023)
profile, and endothelial cell dysfunction. Indeed, increased generation of free radicals as well as immunosenescence are ... |
Trabajo Fin de Grado
Mecanismos moleculares del efecto antienvejecimiento del ejercicio físico
(2022)
El envejecimiento es un proceso natural y gradual que se da en todos los seres vivos. Debido al aumento de la esperanza ... |
Artículo
The Neurokinin-1 Receptor Is Essential for the Viability of Human Glioma Cells: A Possible Target for Treating Glioblastoma
(Hindawi, 2022)
Background. Glioblastoma or glioma is the most common malignant brain tumor. Patients have a prognosis of approximately ... |
Artículo
Anti-inflammatory effect of Phytomarine R-L compound against lipopolysaccharide- induced pulmonary injury in BALB/c mice
(Functional Food Center Inc., 2022)
Background: This study deals with the induction of lipopolysaccharide induced inflammation in animal model and treating ... |
Artículo
Effect of Age and Lipoperoxidation in Rat and Human Adipose Tissue-Derived Stem Cells
(Hindawi, 2020)
A wide range of clinical applications in regenerative medicine were opened decades ago with the discovery of adult stem ... |
Artículo
Rosmarinus officinalis l. (rosemary): An ancient plant with uses in personal healthcare and cosmetics
(Multidisciplinary Digital Publishing Institute (MDPI), 2020)
This work is a bibliographical review of rosemary (Rosmarinus officinalis) that focuses on the application of derivatives ... |
Patente. Invención
Kit y método de cuantificación de la toxicidad en neuronas de la corteza cerebral para la detección de enfermedades neurodegenerativas
(Oficina Española de Patentes y Marcas (OEPM), 2019)
La presente invención escribe un método electrofisiológico y un kit consistente en una concentración de 10 µM de hidroperóxido ... |
Artículo
Physical exercise and myokines
(Spanish Society of Anti-Aging Medicine and Longevity, 2019)
Among the types of muscles present in the body is skeletal muscle, which is the one that allows the development of physical ... |
Artículo
Dysregulation of the Hippo Pathway Signaling in Aging and Cancer
(Elsevier, 2019)
Human beings are facing emerging degenerative and cancer diseases, in large part, as a consequence of increased life ... |
Artículo
Advantages and Disadvantages of Apoptosis in the Aging Process
(Wiley-Blackwell, 2019)
Researchers cannot predict as yet how long a human being can live. Life expectancy has been steadily increasing in the ... |
Artículo
Cell Tracking, Survival, and Differentiation Capacity of Adipose-Derived Stem Cells After Engraftment in Rat Tissue
(Wiley-Blackwell, 2018)
Adipose tissue is an important source of adipose derived stem cells (ADSCs). These cells have the potential of being used ... |
Trabajo Fin de Grado
La importancia del sueño en el mantenimiento de la salud
(2017)
Los seres humanos pasan aproximadamente alrededor de un tercio de sus vidas dormidos, sin embargo la mayoría de las personas ... |
Artículo
Effect of VBC-1814/7J, a poly-phytocompound, on a non-infectious model of pharyngitis
(Spandidos Publications, 2017)
Pharyngitis presents as an inflammation of the oropharynx, and clinical examination often shows evidence of nasopharyngitis. ... |
Artículo
Immunolocalization of Substance P and NK-1 Receptor in ADIPOSE Stem Cells
(Wiley-Blackwell, 2017)
Substance P (SP) is a neuropeptide belonging to the thachykinin peptide family. SP, after binding to its receptor, the ... |
Artículo
Aging and Oxidative Stress Decrease Pineal Elongation Factor 2: In Vivo Protective Effect of Melatonin in Young Rats Treated With Cumene Hydroperoxide
(Wiley-Blackwell, 2017)
We studied the alterations of Elongation Factor 2 (eEF2) in the pineal gland of aged rats as well as the possible protective ... |
Artículo
Hialuronic acid in sking aging
(Spanish Society of Anti-Aging Medicine and Longevity, 2016)
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Artículo
Time and dose dependent effects of oxidative stress induced by cumene hydroperoxide in neuronal excitability of rat motor cortex neurons
(Elsevier, 2016)
It has been claimed that oxidative stress and the production of reactive oxygen radicals can contribute to neuron degeneration ... |
Tesis Doctoral
Estudio de la viabilidad y diferenciación de las células madre mesenquimales de tejido adiposo en condiciones de estrés oxidativo y envejecimiento. Posibilidad de su uso terapéutico e influencia del factor de elongación 2
(2016)
The present thesis is a compilation of several experiments about the use of adiposederived mesenchymal stem cells (ADSCs) ... |
Trabajo Fin de Grado
Efecto de la suplementación nutricional sobre algunos marcadores utilizados en las consultas antienvejecimiento
(2016)
Hoy en día las personas se preocupan más por su salud, prevenir las enfermedades y controlar el envejecimiento. El ... |
Artículo
Chronic Stress Alters the Expression Levels of Longevity-related Genes in the Rat Hippocampus
(Elsevier, 2016)
The molecular mechanisms underlying the negative effects of psychological stress on cellular stress during aging and ... |
Artículo
Treatment with mesenchymal stem cells in an animal model of parkinson´s disease
(Federation of Anti-Aging Medicine Societies, 2015)
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Tesis Doctoral
Efecto del tratamiento con metformina en el sistema dopaminérgico nigroestriado: posible implicación en la enfermedad de parkinson.
(2014)
La enfermedad de Parkinson (EP) es un desorden relacionado con la edad caracterizado por la degeneración progresiva de las ... |
Artículo
A Double-Blind, RCT Testing Beneficial Modulation of BDNF in Middle-Aged, Life Style-Stressed Subjects: A Clue to Brain Protection?
(JCDR, 2014)
Introduction: The aim of this prospective study was to see whether LD-1227, a quality-controlled marine nutraceuticals shown ... |
Artículo
Lipid peroxidation: Production, metabolism, and signaling mechanisms of malondialdehyde and 4-hydroxy-2-nonenal
(Hindawi Publishing Corporation, 2014)
Lipid peroxidation can be described generally as a process under which oxidants such as free radicals attack lipids ... |
Artículo
Elongation factor 2-diphthamide is critical for translation of two IRES-dependent protein targets, XIAP and FGF2, under oxidative stress conditions
(Elsevier, 2013)
Elongation factor-2 (eEF2) catalyzes the movement of the ribosome along the mRNA. A single histidine residue in eEF2 (H715) ... |
Artículo
Molecular Control of the Amount, Subcellular Location and Activity State of Translation Elongation Factor 2 (eEF-2) in Neurons Experiencing Stress
(Eslsevier, 2013)
Eukaryotic elongation factor 2 (eEF-2) is an important regulator of the protein translation machinery wherein it controls ... |
Artículo
Folic acid supplementation: some practical aspects
(Federation of Anti-Aging Medicine Societies, 2012)
Since 1956, when Harman first postulated the free radical theory of aging, numerous studies have been carried out to test ... |
Artículo
In vitro and in Vivo Protection by Melatonin Against the Decline of Elongation Factor-2 Caused by Lipid Peroxidation: Preservation of Protein Synthesis
(Wiley-Blackwell, 2012)
As organisms age, a considerable decrease in protein synthesis takes place in all tissues. Among the possible causes of ... |
| Capítulo de Libro |
Artículo
Potential use of adipose tissue stem cells in the control of aging
(Federation of Anti-Aging Medicine Societies, 2012)
Cell therapy with adult stem cells is a new battle front for the control of aging. Before being used for this purpose, we ... |
Artículo
Mitochondrial toxins and neurodegenerative diseases
(IMR Press, 2007)
The selective loss of a particular subset of neurons is a common feature of neurodegenerative disorders. A failure in ... |
Artículo
Oxidative stress is increased in critically ill patients according to antioxidant vitamins intake, independent of severity: A cohort study
(Springer Science + Business Media, 2006)
Critically ill patients suffer from oxidative stress caused by reactive oxygen species (ROS) and reactive nitrogen species ... |
Artículo
Stress Increases Vulnerability to Inflammation in the Rat Prefrontal Cortex
(Society for Neuroscience, 2006)
Inflammation could be involved in some neurodegenerative disorders that accompany signs of inflammation. However, because ... |
Tesis Doctoral
Estudio de los efectos producidos por la administración crónica de manganeso: implicación de la ingesta de hierro
(2005)
En la tesis titulada "Estudio de los efectos producidos por la administración crónica de manganeso: implicación de la ... |
| Tesis Doctoral |
Artículo
Impairment of mineralocorticoid receptor (MR)-dependent biological response by oxidative stress and aging
(American Society for Biochemistry and Molecular Biology, 2002)
Acute and chronic treatments of mice with the gluta- thione-depleting agent, L-buthionine-(SR)-sulfoximine (BSO), impaired ... |
| Tesis Doctoral |
Tesis Doctoral
Sintesis de proteinas y envejecimiento: papel de los radicales libres
(1997)
El principal objetivo de este trabajo es estudiar el mecanismo por el cual la síntesis de proteínas disminuye durante el ... |
Artículo
Effect of oxidative stress, produced by cumene hydroperoxide, on the various steps of protein synthesis. Modifications of elongation factor-2
(American Society for Biochemistry and Molecular Biology, 1996)
We have studied the effect of oxidative stress on protein synthesis in rat liver. Cumene hydroperoxide (CH) was used as ... |
Tesis Doctoral
Estudio de la regulación a largo plazo de las enzimas productoras de NADPH implicación del requerimiento de NADPH
(1986)
El NADPH es uno de los principales productos finales de los procesos metabólicos, siendo al mismo tiempo sustrato de importantes reacciones metabólicas y de destoxificación.| |