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Multifunctional Eu-doped NaGd(MoO4)2 nanoparticles functionalized with poly(L-lysine) for optical and MRI imaging

 

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Opened Access Multifunctional Eu-doped NaGd(MoO4)2 nanoparticles functionalized with poly(L-lysine) for optical and MRI imaging
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Author: Laguna, Mariano
Núñez Álvarez, Nuria Ofelia
Rodríguez, Verónica
Cantelar, Eugenio
Stepien, Grazyna
García Martín, María L.
Fuente, Jesús M. de la
Ocaña Jurado, Manuel
Date: 2016
Published in: Dalton Transactions, 45 (41), 16354-16365.
Document type: Article
Abstract: A method for the synthesis of non-aggregated and highly uniform Eu3+ doped NaGd(MoO4)2 nanoparticles is reported for the first time. The obtained particles present tetragonal structure, ellipsoidal shape and their size can be varied by adjusting the experimental synthesis parameters. These nanoparticles, which were coated with citrate anions and functionalised with PLL, have also been developed in order to improve their colloidal stability in physiological medium (2-(N-morpholino)ethanesulfonic acid, MES). A study of the luminescent dynamics of the samples as a function of the Eu doping level has been conducted in order to find the optimum nanophosphors, whose magnetic relaxivity and cell viability have also been evaluated for the first time for this system, in order to assess their suitability as multifunctional probes for optical (in vitro) and magnetic bioimaging applications
Cite: Laguna, M., Núñez Álvarez, N.O., Rodríguez, V., Cantelar, E., Stepien, G., García Martín, M.L.,...,Ocaña Jurado, M. (2016). Multifunctional Eu-doped NaGd(MoO4)2 nanoparticles functionalized with poly(L-lysine) for optical and MRI imaging. Dalton Transactions, 45 (41), 16354-16365.
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URI: https://hdl.handle.net/11441/80193

DOI: 10.1039/c6dt02663j

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