dc.creator | Domínguez, Raúl | es |
dc.creator | Sánchez Oliver, Antonio Jesús | es |
dc.creator | Mata Ordoñez, Fernando | es |
dc.creator | Feria Madueño, Adrian | es |
dc.creator | Grimaldi Puyana, Moisés | es |
dc.creator | López Samanes, Álvaro | es |
dc.creator | Pérez López, Alberto | es |
dc.date.accessioned | 2018-05-28T09:22:39Z | |
dc.date.available | 2018-05-28T09:22:39Z | |
dc.date.issued | 2018-02-14 | |
dc.identifier.citation | Domínguez, R., Sánchez Oliver, A.J., Mata Ordoñez, F., Feria Madueño, A., Grimaldi Puyana, M., López Samanes, Á. y Pérez López, A. (2018). Effects of an acute exercise bout on serum hepcidin levels. Nutrients, 2018 (10), 1-22. | |
dc.identifier.uri | https://hdl.handle.net/11441/75215 | |
dc.description.abstract | Iron deficiency is a frequent and multifactorial disorder in the career of athletes, particularly
in females. Exercise-induced disturbances in iron homeostasis produce deleterious effects on
performance and adaptation to training; thus, the identification of strategies that restore or maintain
iron homeostasis in athletes is required. Hepcidin is a liver-derived hormone that degrades the
ferroportin transport channel, thus reducing the ability of macrophages to recycle damaged iron, and
decreasing iron availability. Although it has been suggested that the circulating fraction of hepcidin
increases during early post-exercise recovery (~3 h), it remains unknown how an acute exercise bout
may modify the circulating expression of hepcidin. Therefore, the current review aims to determine
the post-exercise expression of serum hepcidin in response to a single session of exercise. The review
was carried out in the Dialnet, Elsevier, Medline, Pubmed, Scielo and SPORTDiscus databases, using
hepcidin (and “exercise” or “sport” or “physical activity”) as a strategy of search. A total of 19 articles
were included in the review after the application of the inclusion/exclusion criteria. This search
found that a single session of endurance exercise (intervallic or continuous) at moderate or vigorous
intensity (60–90% VO2peak) stimulates an increase in the circulating levels of hepcidin between 0 h
and 6 h after the end of the exercise bout, peaking at ~3 h post-exercise. The magnitude of the
response of hepcidin to exercise seems to be dependent on the pre-exercise status of iron (ferritin) and
inflammation (IL-6). Moreover, oxygen disturbances and the activation of a hypoxia-induced factor
during or after exercise may stimulate a reduction of hepcidin expression. Meanwhile, cranberry
flavonoids supplementation promotes an anti-oxidant effect that may facilitate the post-exercise
expression of hepcidin. Further studies are required to explore the effect of resistance exercise on
hepcidin expression. | es |
dc.format | application/pdf | es |
dc.language.iso | eng | es |
dc.publisher | MDPI | es |
dc.relation.ispartof | Nutrients, 2018 (10), 1-22. | |
dc.rights | Atribución-NoComercial-SinDerivadas 3.0 Estados Unidos de América | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | * |
dc.subject | Iron metabolism | es |
dc.subject | Anemia | es |
dc.subject | Endurance | es |
dc.subject | Exercise | es |
dc.subject | Sport | es |
dc.subject | Sport performance | es |
dc.title | Effects of an acute exercise bout on serum hepcidin levels | es |
dc.type | info:eu-repo/semantics/article | es |
dcterms.identifier | https://ror.org/03yxnpp24 | |
dc.type.version | info:eu-repo/semantics/publishedVersion | es |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | es |
dc.contributor.affiliation | Universidad de Sevilla. Departamento de Educación Física y Deporte | es |
dc.relation.publisherversion | http://dx.doi.org/10.3390/nu10020209 | es |
dc.identifier.doi | 10.3390/nu10020209 | es |
idus.format.extent | 22 p. | es |
dc.journaltitle | Nutrients | es |
dc.publication.volumen | 2018 | es |
dc.publication.issue | 10 | es |
dc.publication.initialPage | 1 | es |
dc.publication.endPage | 22 | es |