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Artículo
Universal structures of normal and pathological heart rate variability
dc.creator | Gañán-Calvo, Alfonso M. | es |
dc.creator | Fajardo-López, Juan | es |
dc.date.accessioned | 2018-02-02T16:46:45Z | |
dc.date.available | 2018-02-02T16:46:45Z | |
dc.date.issued | 2016 | |
dc.identifier.citation | Gañán-Calvo, Alfonso M. y Fajardo-López, J. (2016). Universal structures of normal and pathological heart rate variability. Scientific Reports, 6 (21749) | |
dc.identifier.issn | 2045-2322 | es |
dc.identifier.uri | https://hdl.handle.net/11441/69942 | |
dc.description.abstract | The circulatory system of living organisms is an autonomous mechanical system softly tuned with the respiratory system, and both developed by evolution as a response to the complex oxygen demand patterns associated with motion. Circulatory health is rooted in adaptability, which entails an inherent variability. Here, we show that a generalized N-dimensional normalized graph representing heart rate variability reveals two universal arrhythmic patterns as specific signatures of health one reflects cardiac adaptability, and the other the cardiac-respiratory rate tuning. In addition, we identify at least three universal arrhythmic profiles whose presences raise in proportional detriment of the two healthy ones in pathological conditions (myocardial infarction; heart failure; and recovery from sudden death). The presence of the identified universal arrhythmic structures together with the position of the centre of mass of the heart rate variability graph provide a unique quantitative assessment of the healthpathology gradient. | es |
dc.format | application/pdf | es |
dc.language.iso | eng | es |
dc.publisher | Nature Publishing Group | es |
dc.relation.ispartof | Scientific Reports, 6 (21749) | |
dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 Internacional | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | * |
dc.subject | Universal structures | es |
dc.subject | Pathological heart rate variability | es |
dc.title | Universal structures of normal and pathological heart rate variability | es |
dc.type | info:eu-repo/semantics/article | es |
dcterms.identifier | https://ror.org/03yxnpp24 | |
dc.type.version | info:eu-repo/semantics/publishedVersion | es |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | es |
dc.contributor.affiliation | Universidad de Sevilla. Departamento de Ingeniería Aeroespacial y Mecánica de Fluidos | es |
dc.relation.publisherversion | https://www.nature.com/articles/srep21749 | es |
dc.identifier.doi | 10.1038/srep21749. | es |
idus.format.extent | 11 p. | es |
dc.journaltitle | Scientific Reports | es |
dc.publication.volumen | 6 | es |
dc.publication.issue | 21749 | es |
dc.identifier.sisius | 21027932 | es |
Ficheros | Tamaño | Formato | Ver | Descripción |
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universal.pdf | 884.9Kb | [PDF] | Ver/ | |