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TRIQ: A Comprehensive Evaluation Measure for Triclustering Algorithms

Opened Access TRIQ: A Comprehensive Evaluation Measure for Triclustering Algorithms

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Autor: Gutiérrez Avilés, David
Rubio Escudero, Cristina
Departamento: Universidad de Sevilla. Departamento de Lenguajes y Sistemas Informáticos
Fecha: 2016
Publicado en: HAIS 2016: 11th International Conference on Hybrid Artificial Intelligence Systems (2016), p 673-684
ISBN/ISSN: 978-3-319-32033-5
Tipo de documento: Ponencia
Resumen: Triclustering has shown to be a valuable tool for the analysis of microarray data since its appearance as an improvement of classical clustering and biclustering techniques. Triclustering relaxes the constraints for grouping and allows genes to be evaluated under a subset of experimental conditions and a subset of time points simultaneously. The authors previously presented a genetic algorithm, TriGen, that finds triclusters of gene expression dasta. They also defined three different fitness functions for TriGen: MSR3D, LSL and MSL. In order to asses the results obtained by application of TriGen, a validity measure needs to be defined. Therefore, we present TRIQ, a validity measure which combines information from three different sources: (1) correlation among genes, conditions and times, (2) graphic validation of the patterns extracted and (3) functional annotations for the genes extracted.
Cita: Gutiérrez Avilés, D. y Rubio Escudero, C. (2016). TRIQ: A Comprehensive Evaluation Measure for Triclustering Algorithms. En HAIS 2016: 11th International Conference on Hybrid Artificial Intelligence Systems (673-684), Sevilla, España: Springer.
Tamaño: 178.4Kb
Formato: PDF

URI: http://hdl.handle.net/11441/65813

DOI: 10.1007/978-3-319-32034-2_56

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