Repositorio de producción científica de la Universidad de Sevilla

Spatial Fluctuations in Expression of the Heterocyst Differentiation Regulatory Gene hetR in Anabaena Filaments

Opened Access Spatial Fluctuations in Expression of the Heterocyst Differentiation Regulatory Gene hetR in Anabaena Filaments

Citas

buscar en

Estadísticas
Icon
Exportar a
Autor: Corrales Guerrero, Laura
Tal, Asaf
Arbel Goren, Rinat
Mariscal, Vicente
Flores Garcia, Enrique
Herrero, Antonia
Stavans, Joel
Departamento: Universidad de Sevilla. Departamento de Bioquímica Vegetal y Biología Molecular
Fecha: 2015
Publicado en: PLoS Genetics, 11 (4), e1005031-1-e1005031-21.
Tipo de documento: Artículo
Resumen: Under nitrogen deprivation, filaments of the cyanobacterium Anabaena undergo a process of development, resulting in a one-dimensional pattern of nitrogen-fixing heterocysts separated by about ten photosynthetic vegetative cells. Many aspects of gene expression before nitrogen deprivation and during the developmental process remain to be elucidated. Furthermore, the coupling of gene expression fluctuations between cells along a multicellular filament is unknown. We studied the statistics of fluctuations of gene expression of HetR, a transcription factor essential for heterocyst differentiation, both under steady-state growth in nitrogen-rich conditions and at different times following nitrogen deprivation, using a chromosomally-encoded translational hetR-gfp fusion. Statistical analysis of fluorescence at the individual cell level in wild-type and mutant filaments demonstrates that expression fluctuations of hetR in nearby cells are coupled, with a characteristic spatial range of circa...
[Ver más]
Cita: Corrales Guerrero, L., Tal, A., Arbel Goren, R., Mariscal, V., Flores Garcia, E., Herrero, A. y Stavans, J. (2015). Spatial Fluctuations in Expression of the Heterocyst Differentiation Regulatory Gene hetR in Anabaena Filaments. PLoS Genetics, 11 (4), e1005031-1-e1005031-21.
Tamaño: 2.370Mb
Formato: PDF

URI: http://hdl.handle.net/11441/64060

DOI: 10.1371/journal.pgen.1005031

Ver versión del editor

Mostrar el registro completo del ítem


Esta obra está bajo una Licencia Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 Internacional

Este registro aparece en las siguientes colecciones