dc.creator | Pérez Jiménez, Mario de Jesús | es |
dc.creator | Romero Campero, Francisco José | es |
dc.date.accessioned | 2017-01-30T06:41:41Z | |
dc.date.available | 2017-01-30T06:41:41Z | |
dc.date.issued | 2005 | |
dc.identifier.citation | Pérez Jiménez, M.d.J., y Romero Campero, F.J. (2005). A Study of the Robustness of the EGFR Signalling Cascade Using Continuous Membrane Systems. En Mechanisms, Symbols, and Models Underlying Cognition. IWINAC 2005. Lecture Notes in Computer Science, vol 3561 (pp. 268-278). Berlin: Springer. | |
dc.identifier.isbn | 978-3-540-26298-5 | es |
dc.identifier.issn | 0302-9743 | es |
dc.identifier.uri | http://hdl.handle.net/11441/52924 | |
dc.description.abstract | Many approaches to anticancer treatment have had a limited
success. A fundamental hurdle to cancer therapy is the robustness of the
signalling networks involved in tumourgenesis. The complexity of net-
works of biological signalling pathways is such that the development of
simplifying models is essential in trying to understand the wide-ranging
cellular responses they can generate. In this paper a model of the epider-
mal growth factor receptor signalling cascade is developed using contin-
uous membrane systems. This model is used to study the robustness of
this signalling cascade which is known to play a key role in tumour cell
proliferation, angiogenesis and metastasis. | es |
dc.description.sponsorship | Ministerio de Ciencia y Tecnología TIC2002-04220-C03-01 | |
dc.format | application/pdf | es |
dc.language.iso | eng | es |
dc.publisher | Springer | es |
dc.relation.ispartof | Mechanisms, Symbols, and Models Underlying Cognition. IWINAC 2005. Lecture Notes in Computer Science, vol 3561 | es |
dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 Internacional | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | * |
dc.subject | Membrane computing | es |
dc.subject | EGFR signalling network | es |
dc.subject | signal transduction | es |
dc.subject | robustness | es |
dc.title | A Study of the Robustness of the EGFR Signalling Cascade Using Continuous Membrane Systems | es |
dc.type | info:eu-repo/semantics/bookPart | es |
dcterms.identifier | https://ror.org/03yxnpp24 | |
dc.type.version | info:eu-repo/semantics/acceptedVersion | es |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | es |
dc.contributor.affiliation | Universidad de Sevilla. Departamento de Ciencias de la Computación e Inteligencia Artificial | es |
dc.relation.projectID | TIC2002-04220-C03-01 | es |
dc.relation.publisherversion | http://link.springer.com/chapter/10.1007%2F11499220_28 | es |
dc.identifier.doi | 10.1007/11499220_28 | es |
dc.contributor.group | Universidad de Sevilla. TIC193 : Computación Natural | es |
idus.format.extent | 11 | es |
dc.publication.initialPage | 268 | es |
dc.publication.endPage | 278 | es |
dc.relation.publicationplace | Berlin | es |
dc.contributor.funder | Ministerio de Ciencia y Tecnología (MCYT). España | |