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Estudio de la citotoxicidad de cerámicas biomórficas de SiC recubiertas con vidrio bioactivo

 

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Opened Access Estudio de la citotoxicidad de cerámicas biomórficas de SiC recubiertas con vidrio bioactivo
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Author: Borrajo, J. P.
González, P.
Serra, J.
Liste, S.
Chiussi, S.
León, B.
Carlos Villamarín, Alejandro de
Varela Feria, Francisco Manuel
Martínez Fernández, Julián
Ramírez de Arellano López, Antonio
Department: Universidad de Sevilla. Departamento de Física de la Materia Condensada
Date: 2006
Published in: Boletín de la Sociedad Española de Cerámica y Vidrio, 45(2), 109-114
Document type: Article
Abstract: La necesidad de desarrollar nuevos implantes basados en materiales bioactivos que sean capaces de soportar grandes cargas mecánicas ha llevado a la producción de sustratos metálicos recubiertos con cerámicas bioactivas. Recientemente se ha propues...
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In the past years there was a need to develop new tough bioactive materials capable to resist high loads when implanted in the body, that led to the production of bioactive coatings on metallic substrates. A new approach, which consists of biomorphic silicon carbide (SiC) coated with bioactive glass by Pulsed Laser Deposition (PLD), was recently presented. This new material joins the high mechanical strength, lightness and porosity of biomorphic SiC and the bioactive properties of PLD glass films. In this work, a multiple evaluation of this new material is presented starting from the biomorphic SiC morphology and porosity, following with the bioactivity in simulated body fluid of the coatings, and ending with a deep in vitro study with MG-63 cells. The citotoxicity of the SiC coated and uncoated and the cell proliferation and attachment were studied.
Size: 849.5Kb
Format: PDF

URI: http://hdl.handle.net/11441/22696

DOI: 10.3989/cyv.2006.v45.i2.321

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