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- Centro Andaluz de Biología Molecular y Medicina Regenerativa (CABIMER)
- Listar Centro Andaluz de Biología Molecular y Medicina Regenerativa (CABIMER) por autor
Listar Centro Andaluz de Biología Molecular y Medicina Regenerativa (CABIMER) por autor "Zeng, Zhihong"
Mostrando ítems 1-2 de 2
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Artículo
TDP2-Dependent Non-Homologous End-Joining Protects against Topoisomerase II-Induced DNA Breaks and Genome Instability in Cells and In Vivo
Gómez Herreros, Fernando; Romero Granados, Rocío; Zeng, Zhihong; Álvarez Quilón, Alejandro; Quintero Ruiz, María Cristina; Ju, Limei; Umans, Lieve; Vemeire, Liesbeth; Huylebroeck, Danny; Caldecott, Keith W.; Cortés Ledesma, Felipe (Public Library of Science, 2013)Anticancer topoisomerase >poisons> exploit the break-and-rejoining mechanism of topoisomerase II (TOP2) to generate ...
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Artículo
TDP2/TTRAP Is the Major 5′-Tyrosyl DNA Phosphodiesterase Activity in Vertebrate Cells and Is Critical for Cellular Resistance to Topoisomerase II-induced DNA Damage
Zeng, Zhihong; Cortés Ledesma, Felipe; El Khamisy, Sherif F.; Caldecott, Keith W. (American Society for Biochemistry and Molecular Biology, 2011)Topoisomerase II (Top2) activity involves an intermediate in which the topoisomerase is covalently bound to a DNA double-strand ...