• Artículo
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      Endogenous topoisomerase II-mediated DNA breaks drive thymic cancer predisposition linked to ATM deficiency 

      Álvarez Quilón, Alejandro; Terrón Bautista, José; Delgado Sainz, Irene; Serrano Benítez, Almudena; Romero Granados, Rocío; Martínez García, Pedro Manuel; Jimeno González, Silvia; Bernal Lozano, Cristina; Quintero, Cristina; García Quintanilla, Lourdes; Cortés Ledesma, Felipe (Springer Nature, 2020)
      The ATM kinase is a master regulator of the DNA damage response to double-strand breaks (DSBs) and a well-established ...
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      TDP2 suppresses genomic instability induced by androgens in the epithelial cells of prostate glands 

      Al Mahmud, Md Rasel; Ishii, Kenichiro; Bernal Lozano, Cristina; Delgado Sainz, Irene; Toi, Masakazu; Akamatsu, Shusuke; Fukumoto, Manabu; Watanabe, Masatoshi; Takeda, Shunichi; Cortés Ledesma, Felipe; Sasanuma, Hiroyuki (Wiley-Blackwell, 2020)
      Androgens stimulate the proliferation of epithelial cells in the prostate by activating topoisomerase 2 (TOP2) and regulating ...