Listar Artículos (Química Orgánica y Farmacéutica) por título
Mostrando ítems 100-119 de 177
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N -Isopropylsulfinylimines vs. N-tert -butylsulfinylimines in the stereoselective synthesis of sterically hindered amines: An improved synthesis of enantiopure (R)- And (S)-rimantadine and the trifluoromethylated analogues
(Royal Society of Chemistry, 2019-11-04)An improved fully stereoselective synthesis of both enantiomers of rimantadine and its trifluoromethylated analogues has ...
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Nanocomposites of Microbial Polyglutamic Acid and Nanoclays Compatibilized by Organophosphonium Surfactants
(Wiley, 2018)Ionic coupling of bacterial poly(γ-glutamic acid) (PGGA) with alkyltrimethylphosphonium surfactants is reported to render ...
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Nanostructured Chitosan-Based Biomaterials for Sustained and Colon-Specific Resveratrol Release
(MDPI, 2019-01)In the present work, we demonstrate the preparation of chitosan-based composites as vehicles of the natural occurring ...
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Native Chilean Berries Preservation and In Vitro Studies of a Polyphenol Highly Antioxidant Extract from Maqui as a Potential Agent against Inflammatory Diseases
(MDPI, 2021-05)The best conservation method for native Chilean berries has been investigated in combination with an implemented large-scale ...
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Neuroprotective and Anti-inflammatory Effects of Pterostilbene Metabolites in Human Neuroblastoma SH-SY5Y and RAW 264.7 Macrophage Cells
(American Chemical Society, 2020)Oxidative stress is known to be a key factor in many neurodegenerative diseases. Inflammation also plays a relevant role ...
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New Oleoyl Hybrids of Natural Antioxidants: Synthesis and In Vitro Evaluation as Inducers of Apoptosis in Colorectal Cancer Cells
(MDPI, 2020)Nowadays, the beneficial role of a healthy lifestyle, particularly emphasizing the quality of foods and cancer management, ...
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New sulfur-phosphine ligands derived from sugars: synthesis and application in palladium-catalyzed allylic alkylation and in rhodium asymmetric hydrogenation
(Arkat USA, 2008)An efficient route to mixed phosphine / thioglycoside ligands type IV starting from glucose pentaacetate is reported. In ...
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NMR study on the stabilization and chiral discrimination of sulforaphane enantiomers and analogues by cyclodextrins
(Elsevier, 2018)Sulforaphane (SFN), a phytochemical isolated from broccoli, is an important antitumoral compound with additional beneficial ...
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Novel poly(azoamide triazole)s containing twin azobenzene units in the backbone. Synthesis, characterization, and in vitro degradation studies
(Elsevier, 2021)We describe the synthesis and characterization of four new light and reduction sensitives poly(azoamide triazole)s, in ...
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Novel Utilization of Therapeutic Coatings Based on Infiltrated Encapsulated Rose Bengal Microspheres in Porous Titanium for Implant Applications
(MDPI, 2022-06)Despite the increasing progress achieved in the last 20 years in both the fabrication of porous dental implants and the ...
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Passive targeting of high-grade gliomas via the EPR effect: a closed path for metallic nanoparticles?
(Royal Society of Chemistry, 2021-10-28)Passive tumor targeting via the enhanced permeability and retention (EPR) effect has long been considered the most effective ...
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PEGylated Terbium-Based Nanorods as Multimodal Bioimaging Contrast Agents
(American Chemical Society, 2021)Diagnostic imaging strongly relies on the use of contrast agents (CAs). In general terms, current CAs present undesirable ...
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PEGylated terbium-based nanorods as multimodal bioimaging contrast agents
(American Chemical Society, 2021-03)Diagnostic imaging strongly relies on the use of contrast agents (CAs). In general terms, current CAs present undesirable ...
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pH-Responsive Polymeric Nanoparticles as Drug Delivery Systems
(JSciMed Central, 2017-04)Micelles are excellent devices to be used as controlled drug delivery systems since they exhibit the ability to protect ...
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Phosphinite Thioglycosides Derived from Natural D-Sugars as Useful P/S Ligands for the Synthesis of Both Enantiomers in Palladium-Catalyzed Asymmetric Substitution
(Georg Thieme Verlag, 2005)Phosphinite thioglycosides I for which a modular synthetic approach is reported, were found highly efficient catalyst ...
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Piperazine-derived small molecules as potential Flaviviridae NS3 protease inhibitors. In vitro antiviral activity evaluation against Zika and Dengue viruses
(Elsevier, 2023)Since 2011 Direct Acting antivirals (DAAs) drugs targeting different non-structural (NS) viral proteins (NS3, NS5A or NS5B ...
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Polymeric nanoparticles for drug delivery: Recent developments and future prospects
(Multidisciplinary Digital Publishing Institute (MDPI), 2020)The complexity of some diseases—as well as the inherent toxicity of certain drugs—has led to an increasing interest in the ...
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Polyphenolic Maqui Extract as a Potential Nutraceutical to Treat TNBS-Induced Crohn' s Disease by the Regulation of Antioxidant and Anti-Inflammatory Pathways
(MDPI, 2020)Nutraceuticals include a wide variety of bioactive compounds, such as polyphenols, which have been highlighted for their ...
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Porous beta titanium alloy coated with a therapeutic biopolymeric composite to improve tribomechanical and biofunctional balance
(Elsevier, 2023-05)Tooth loss is common in patients struggling with dental cavities, periodontal diseases, and tumors, as well as those who ...
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Porous titanium substrates coated with a bilayer of bioactive glasses
(Elsevier, 2020-09)Porous titanium substrates coated by dripping-sedimentation technique with a novel bilayer of (45S5 / 1393) bioactive ...