Article
Phosphinite Thioglycosides Derived from Natural D-Sugars as Useful P/S Ligands for the Synthesis of Both Enantiomers in Palladium-Catalyzed Asymmetric Substitution
Author/s | Khiar, Noureddine
Suárez, Belén Valdivia Giménez, Victoria Esther Fernández Fernández, Inmaculada |
Department | Universidad de Sevilla. Departamento de Química Orgánica y Farmacéutica |
Publication Date | 2005 |
Deposit Date | 2016-07-04 |
Published in |
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Abstract | Phosphinite thioglycosides I for which a modular synthetic approach is reported, were found highly efficient catalyst precursors for palladium(0)-catalyzed asymmetric substitution. Both enantiomers of the allylated products ... Phosphinite thioglycosides I for which a modular synthetic approach is reported, were found highly efficient catalyst precursors for palladium(0)-catalyzed asymmetric substitution. Both enantiomers of the allylated products have been obtained with high ee (up to 96%) using natural sugars as catalyst precursors. |
Funding agencies | Ministerio de Educación y Ciencia (MEC). España Fundación Ramón Areces |
Project ID. | PB BQU2003-00937
CTQ2004-01057 |
Citation | Khiar, N., Suárez, B., Valdivia Giménez, V.E. y Fernández Fernández, I. (2005). Phosphinite Thioglycosides Derived from Natural D-Sugars as Useful P/S Ligands for the Synthesis of Both Enantiomers in Palladium-Catalyzed Asymmetric Substitution. Synlett, 19, 2963-2967. |
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