Listar Artículos (Química Orgánica y Farmacéutica) por título
Mostrando ítems 23-42 de 171
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Artículo
Carbohydrate-Based NK1R Antagonists with Broad-Spectrum Anticancer Activity
(American Chemical Society, 2021)NK1R antagonists, investigated for the treatment of several pathologies, have shown encouraging results in the treatment ...
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Carbohydrate-DNA interactions at G-quadruplexes: Folding and stability changes by attaching sugars at the 5′-End
(Wiley-Blackwell, 2013)Quadruplex DNA structures are attracting an enormous interest in many areas of chemistry, ranging from chemical biology, ...
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Chiral sulfur derivatives in the allylation of acyl hydrazones: C 2-symmetric bis-sulfinamides as enhanced chiral organic promoters
(Royal Society of Chemistry, 2010-10)Monosulfinamides and C2-symmetric bis-sulfinamides are convenient neutral chiral promoters in the allylation of acyl ...
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Clickable iron oxide NPs based on catechol derived ligands: synthesis and characterization
(Taylor and Francis Group, 2020-03-05)Clickable magnetic nanoparticles have attracted great attention as potential nanoplatforms for biomedical applications ...
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Collecting high-order interactions in an effective pairwise intermolecular potential using the hydrated ion concept: The hydration of Cf3+
(American Institute of Physics Publising LLC, 2014)This work proposes a new methodology to build interaction potentials between a highly charged metal cation and water ...
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Comparative cytotoxic activity of hydroxytyrosol and its semisynthetic lipophilic derivatives in prostate cancer cells
(Multidisciplinary Digital Publishing Institute (MDPI), 2021)A high adherence to a Mediterranean diet has been related to numerous beneficial effects in human health, including a lower ...
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Comparative evaluation of the metabolic effects of hydroxytyrosol and its lipophilic derivatives (hydroxytyrosyl acetate and ethyl hydroxytyrosyl ether) in hypercholesterolemic rats
(Royal Society of Chemistry, 2014)Hydroxytyrosol (HT), a virgin olive oil phenolic phytochemical with proven health benefits, has been used to generate new ...
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Comparison of the anti-angiogenic potential of hydroxytyrosol and five derivatives
(Royal Society of Chemistry, 2018)Hydroxytyrosol is a phenolic compound present in extra virgin olive oil, either in free form or as derivatives, and related ...
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Comprehensive Toxicity Assessment of PEGylated Magnetic Nanoparticles for in vivo applications
(Elsevier, 2019-05-01)Magnetic nanoparticles (MNPs) represent one of the greatest promises for the development of a new generation of diagnostic ...
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Conformations in crystals and solutions of d(CACGTG), d(CCGCGG) and d(GGCGCC) studied by vibrational spectroscopy
(IRL Press, 1989)Crystals of self camplementary DMA hexamers dCCACGTG>, dCCCGCGG> and d<GGCGCC> were grown bf vapour dlffuslon technlque ...
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Core cross-linked nanoparticles from self-assembling polyfma-based micelles. Encapsulation of lipophilic molecules
(Elsevier, 2017-04)The present work describes the preparation of stable organic nanoparticles with potential use as “smart” drug delivery ...
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Cytotoxic, Antiangiogenic and Antitelomerase Activity of Glucosyl- and Acyl- Resveratrol Prodrugs and Resveratrol Sulfate Metabolites
(Wiley-Blackwell, 2016)Resveratrol (RES) is a natural polyphenol with relevant and varied biological activity. However, its low bioavailability ...
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Deciphering the Parameters to Produce Highly Reproducible and Scalable Iron Oxide Nanoparticles
(Royal Society of Chemistry, 2023)Nanomedicine has been long hailed as a game changer for treating several ailments, but its translation from bench to bedside ...
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Derivados del pirrol xxi. Reaccion de 2-amin0-2-desoxi-heptosas con 2,4-pentanodiona y 1-fenil-1,3-butanodiona
(1979)Por reacción de las 2-amino-2-<lesoxi·heptosas de configuraciones D-glieero·L·glueo (la). D·glieero·D-talo (lb) y ...
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Derivados del pirrol. XXIII. Reacción de 2-amin0-2-desoxi-heptosas con benzoilacetaldehido
(1980)Por reacción de benzoilcetaldehfdo con 2-amino-2-desoxi-heptosas de configuraciones D·glicero-D·talo (1 b) y D·glicero·D·ido ...
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Design and manufacturing by fused filament technique of novel YSZ porous grafts infiltrated with PCL/PVA/AgNPs for large bone defects repairing
(Elsevier, 2024-02-19)Addressing large bone segmental defects remains a profound challenge in orthopaedic surgery, demanding graft designs that ...
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Ponencia
Design and synthesis of supramolecular hydrogels for biomedical applications
(Universidad Pablo de Olavide, 2016)Motivation: Only a few cells in the human organism keep their ability to regenerate. Hence, modern medical research intends ...
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Design of highly stabilized nanocomposite inks based on biodegradable polymer-matrix and gold nanoparticles for Inkjet Printing
(Nature Research, 2019)Nowadays there is a worldwide growing interest in the Inkjet Printing technology owing to its potentially high levels of ...
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Design, synthesis and biological studies of a library of NK1-Receptor Ligands Based on a 5-arylthiosubstituted 2-amino-4,6-diaryl-3-cyano-4H-pyran core: Switch from antagonist to agonist effect by chemical modification
(Elsevier, 2017)A library of 5-arylthiosubstituted 2-amino-4,6-diaryl-3-cyano-4H-pyrans has been synthesized as a new family of non-peptide ...
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Design, synthesis and in vitro biological evaluation of a novel class of anti-adenovirus agents based on 3-amino-1,2-propanediol
(Elsevier, 2021)Nowadays there is not an effective drug for the treatment of infections caused by human adenovirus (HAdV) which supposes ...