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Mostrando ítems 1-10 de 15
Artículo
Development and validation of an RP-HPLC method for CB13 evaluation in several PLGA nanoparticle systems
(Hindawi Publishing Corporation, 2012)
A simple, fast, and reversed-phase high-performance liquid chromatographic (RP-HPLC) method has been developed and validated for determining of a cannabinoid derivate, which displays potent antihyperalgesic activity, ...
Artículo
Evaluation of poly (lactic-co-glycolic acid) nanoparticles to improve the therapeutic efficacy of paclitaxel in breast cancer
(Universidad de Ciencias Médicas de Tabriz, 2022)
Introduction: Paclitaxel (PTX) is a cornerstone in the treatment of breast cancer, the most common type of cancer in women. However, this drug has serious limitations, including lack of tissue-specificity, poor water ...
Artículo
Interés terapéutico de cannabinoides: análisis bibliométrico en Pubmed, Scopus y web of Science
(2013)
En este trabajo se ha analizado la actividad científica mundial sobre la aplicación terapéutica de cannabinoides en diferentes patologías, así como la posible aplicación de la nanotecnología en el desarrollo de nuevos ...
Artículo
Receptor-targeted nanoparticles modulate cannabinoid anticancer activity through delayed cell internalization
(Nature Research, 2022)
Δ9-tetrahydrocannabinol (Δ9-THC) is known for its antitumor activity and palliative effects. However, its unfavorable physicochemical and biopharmaceutical properties, including low bioavailability, psychotropic side effects ...
Artículo
Ophthalmic wild olive (acebuche) oil nanoemulsions exert oculoprotective effects against oxidative stress induced by arterial hypertension
(Elsevier, 2023)
Oxidative stress plays a key role in several systemic and ocular diseases, including hypertensive eye diseases. In this context, we previously showed that oral administration of wild olive (acebuche, ACE) oil from Olea ...
Artículo
Cannabinoid-Based Ocular Therapies and Formulations
(Multidisciplinary Digital Publishing Institute (MDPI), 2023)
Abstract The interest in the pharmacological applications of cannabinoids is largely increasing in a wide range of medical areas. Recently, research on its potential role in eye conditions, many of which are chronic and/or ...
Artículo
Efecto neuroprotector de los cannabinoides en las enfermedades neurodegenerativas
(2015)
Se analiza la situación actual de las investigaciones relacionadas con las sustancias cannabinoides, así como su interacción con el organismo, clasificación, efectos terapéuticos y su uso en las enfermedades neurodegenerativas
Artículo
Cannabinoid derivate-loaded PLGA nanocarriers for oral administration: formulation, characterization, and cytotoxicity studies
(2012)
CB13 (1-Naphthalenyl[4-(pentyloxy)-1-naphthalenyl]methanone)-loaded poly(lactic-co-glycolic acid) nanoparticles (NPs) were produced by nanoprecipitation and tested for their in vitro release behavior and in vitro ...
Artículo
Nuevo concepto de úlcera péptica. Epidemiología
(Alpe Editores, 2001)
En los últimos años se han experimentado cambios importantes en cuanto a la etiología y el tratamiento de las enfermedades del ácido gástrico. Se debió al descubrimiento, por Marshall en 1982, de Helicobacter pylori en la ...
Artículo
Contact lenses as drug-delivery systems: a promising therapeutic tool
(Elsevier, 2020)
The ocular administration of drugs using traditional pharmaceutical forms, including eye drops or ointments, results in low bioavailability, as well as requiring multiple administrations per day, with the consequent danger ...