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Mostrando ítems 1-10 de 32
Artículo
Crosstalk between chromatin structure, cohesin activity and transcription
(BMC (part of Springer Nature), 2019)
Background: A complex interplay between chromatin and topological machineries is critical for genome architec‑ ture and function. However, little is known about these reciprocal interactions, even for cohesin, despite its ...
Artículo
In vitro assessment of the mutagenic and genotoxic potential of a pure stilbene extract
(Elsevier, 2021-04)
Stilbenes are secondary metabolites of great interest produced by many plant species due to their important bioactive properties. These phytochemicals have become of increasing interest in the wine industry as a natural ...
Artículo
In Vivo Genotoxicity Evaluation of a Stilbene Extract Prior to Its Use as a Natural Additive: A Combination of the Micronucleus Test and the Comet Assay
(MDPI, 2021)
Genotoxic data of substances that could be used as food additives are required by the European Food Safety Authority. In this sense, the use of an extract from grapevine shoots containing a stilbene richness of 99% (ST-99), ...
Artículo
Passive targeting of high-grade gliomas via the EPR effect: a closed path for metallic nanoparticles?
(Royal Society of Chemistry, 2021-10-28)
Passive tumor targeting via the enhanced permeability and retention (EPR) effect has long been considered the most effective mechanism for the accumulation of nanoparticles inside solid tumors. However, several studies ...
Artículo
Chrononutrition and Polyphenols: Roles and Diseases
(MDPI, 2019)
Biological rhythms can influence the activity of bioactive compounds, and at the same time, the intake of these compounds can modulate biological rhythms. In this context, chrononutrition has appeared as a research field ...
Artículo
Temporal spectral evolution of pre-stimulus brain activity in visual and visuomotor tasks
(Springer Nature, 2023)
The aim of this study was to describe the spectral features of pre-stimulus event-related potential (ERP) components elicited in visual tasks such as the Bereitschaftspotential (BP), prefrontal negativity (pN) and visual ...
Artículo
Effect of Combination Antibiotic Empirical Therapy on Mortality in Neutropenic Cancer Patients with Pseudomonas aeruginosa Pneumonia
(MDPI, 2022)
To assess the effect of combination antibiotic empirical therapy on 30-day case-fatality rate in neutropenic cancer patients with Pseudomonas aeruginosa (PA) bacteremic pneumonia. This was a multinational, retrospective ...
Artículo
Cytotoxicity studies of a stilbene extract and its main components intended to be used as preservative in the wine industry
(Elsevier, 2020)
The use of stilbenes has been proposed as an alternative to sulfur dioxide in wine. Provided the feasibility from a technological approach, the cytotoxicity of an extract from grapevine shoots containing a stilbene richness ...
Artículo
Different involvement of medial prefrontal cortex and dorso-lateral striatum in automatic and controlled processing of a future conditioned stimulus
(2017)
Recent studies support the idea that stimulus processing in latent inhibition can vary during the course of preexposure. Controlled attentional mechanisms are said to be important in the early stages of preexposure, while ...
Artículo
Trichuris trichiura isolated from Macaca sylvanus: morphological, biometrical, and molecular study
(BioMed Central, 2020)
Background Recent studies have reported the existence of a Trichuris species complex parasitizing primate. Nevertheless, the genetic and evolutionary relationship between Trichuris spp. parasitizing humans and Non-Human ...