Listar Artículos (Instituto de Investigaciones Químicas (IIQ) – CIC Cartuja) por título
Mostrando ítems 56-75 de 284
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Cu(I) and Ag(I) complexes of two sterically demanding Xylyl-Substituted phosphine Ligands: Synthesis, Characterization, and structural examination
(Elsevier, 2023)Two sterically demanding tertiary phosphines, PiPr2Xyl and PtBu2Xyl, (Xyl = 2,6-dimethylphenyl), the latter reported here ...
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Cyclodextrin-based facial amphiphiles: Assessing the impact of the hydrophilic-lipophilic balance in the self-assembly, DNA complexation and gene delivery capabilities
(Royal Society of Chemistry, 2016)Exhaustive structure–efficacy relationship studies on nonviral gene delivery systems are often hampered by the ill-defined ...
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Cyclodextrin-based multivalent glycodisplays: Covalent and supramolecular conjugates to assess carbohydrate-protein interactions
(Royal Society of Chemistry (Great Britain), 2013)Covalent attachment of biorecognizable sugar ligands in several copies at precise positions of cyclomaltooligosaccharide ...
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Cyclodextrin-mediated Crystallization of Acid β-glucosidase in Complex with Amphiphilic Bicyclic Nojirimycin Analogues
(Royal Society of Chemistry, 2011)Cyclodextrin-based host-guest chemistry has been exploited to facilitate co-crystallization of recombinant human acid ...
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Cyclooctyne [60]fullerene hexakis adducts: a globular scaffold for copper-free click chemistry
(Royal Society of Chemistry, 2016)The synthesis of a new highly symmetric hexakis adduct of C60 appended with 12 cyclooctyne moieties has been carried out. ...
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Cytochrome c lysine acetylation regulates cellular respiration and cell death in ischemic skeletal muscle
(Springer Nature, 2023)Skeletal muscle is more resilient to ischemia-reperfusion injury than other organs. Tissue specific post-translational ...
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Cytochrome c speeds up caspase cascade activation by blocking 14-3-3ε-dependent Apaf-1 inhibition
(Nature Publishing Group, 2018)Apoptosis is a highly regulated form of programmed cell death, essential to the development and homeostasis of multicellular ...
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Cytochrome c: Surfing Off of the Mitochondrial Membrane on the Tops of Complexes III and IV
(Elsevier, 2019)The proper arrangement of protein components within the respiratory electron transport chain is nowadays a matter of intense ...
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Deciphering of polycationic carbohydrate based non-viral gene delivery agents by ESI-LTQ-Orbitrap using CID/HCD pairwise tandem mass spectrometry
(Royal Society of Chemistry, 2016)For almost three decades, gene therapy has been gaining interest to efficiently treat some severe diseases. In such context, ...
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Design, synthesis and biological studies of a library of NK1-Receptor Ligands Based on a 5-arylthiosubstituted 2-amino-4,6-diaryl-3-cyano-4H-pyran core: Switch from antagonist to agonist effect by chemical modification
(Elsevier, 2017)A library of 5-arylthiosubstituted 2-amino-4,6-diaryl-3-cyano-4H-pyrans has been synthesized as a new family of non-peptide ...
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Detection and Quantitative Analysis of Two Independent Binding Modes of a Small Ligand Responsible for DC-SIGN Clustering
(Royal Society of Chemistry, 2015)DC-SIGN (dendritic cell-specific ICAM-3 grabbing non-integrin) is a C-type lectin receptor (CLR) present, mainly in dendritic ...
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Development of silica‐based biodegradable submicrometric carriers and investigating their characteristics as in vitro delivery vehicles
(MDPI, 2020)Nanostructured silica (SiO2)-based materials are attractive carriers for the delivery of bioactive compounds into cells. ...
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Dialkylterphenyl Phosphine-Based Palladium Precatalysts for Efficient Aryl Amination of N-Nucleophiles
(Wiley-Blackwell, 2020)A series of 2-aminobiphenyl palladacycles supported by dialkylterphenyl phosphines, PR2Ar′ (R=Me, Et, iPr, Cyp (cyclopentyl), ...
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Dibenzyl and diallyl 2,6-bisiminopyridinezinc (ii) complexes: Selective alkyl migration to the pyridine ring leads to remarkably stable dihydropyridinates
(Royal Society of Chemistry, 2013)Diorganozinc compounds (ZnR2) with R = CH2Ph or CH2CH[double bond, length as m-dash]CH2 react with 2,6-bisiminopyridines ...
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Different coordination modes of an aryl-substituted hydrotris(pyrazolyl) borate ligand in rhodium and iridium complexes
(Elsevier, 2011)Complexes TptolRh(C2H4)2 (1a) and TptolRh(CH2C(Me)C(Me)CH2) (1b) have been prepared by reaction of KTptol with the appropriate ...
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Differential effects of carbohydrates on arabidopsis pollen germination
(Oxford University Press, 2017)Pollen germination as a crucial process in plant development strongly depends on the accessibility of carbon as energy ...
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Dinuclear Cu(I) Halides with Terphenyl Phosphines: Synthesis, Photophysical Studies, and Catalytic Applications in CuAAC Reactions
(American Chemical Society, 2020)Several dinuclear terphenyl phosphine copper(I) halide complexes of composition [CuX(PR2Ar′)]2 (X = Cl, Br, I; R = ...
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Direct evidence for a coordination-insertion mechanism of ethylene oligomerization catalysed by neutral 2,6-bisiminopyridine iron monoalkyl complexes
(Royal Society of Chemistry, 2014)1H NMR studies on ethylene oligomerization catalysed by the neutral monoalkyl complex [Fe(Me)(iPrBIP)] allow direct ...
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Docetaxel-Loaded Nanoparticles Assembled from β-Cyclodextrin/Calixarene Giant Surfactants: Physicochemical Properties and Cytotoxic Effect in Prostate Cancer and Glioblastoma Cells
(Frontiers Media, 2017)Giant amphiphiles encompassing a hydrophilic β-cyclodextrin (βCD) component and a hydrophobic calix[4]arene (CA4) module ...
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Docking, synthesis, and NMR studies of mannosyl trisaccharide ligands for DC-SIGN lectin
(Royal Society of Chemistry (Great Britain), 2008)DC-SIGN, a lectin, which presents at the surface of immature dendritic cells, constitutes nowadays a promising target for ...