Listar Artículos (Instituto de Investigaciones Químicas (IIQ) – CIC Cartuja) por título
Mostrando ítems 46-65 de 284
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Cationic Platinum(II) σ-SiH Complexes in Carbon Dioxide Hydrosilation
(John Wiley & Sons, 2016)The low-electron-count cationic platinum complex [Pt(ItBu’)(ItBu)][BAr], 1, interacts with primary and secondary silanes ...
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Cell uptake mechanisms of glycosylated cationic pDNA-cyclodextrin nanoparticles
(Royal Society of Chemistry, 2015)The incorporation of carbohydrate functional elements in the architecture of polycationic amphiphilic cyclodextrins (paCDs) ...
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Characterization of the kisspeptin system in human sperm
(European Academy of Andrology, 2012)Kisspeptin, the product of the KISS1 gene, plays an essential role in the regulation of spermatogenesis acting primarily ...
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Chiral Rh phosphine–phosphite catalysts immobilized on ionic resins for the enantioselective hydrogenation of olefins in water
(Royal Society of Chemistry, 2015)The asymmetric hydrogenation of prochiral enamides with Rh complexes bearing chiral phosphine–phosphite ligands (P–OP) ...
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Chirality influence on the cytotoxic properties of anionic chiral bis(N-heterocyclic carbene)silver complexes
(Elsevier, 2022)Complexes Na3[Ag(NHCR)2], 2a-e and 2b’-c’, where NHCR is a N-heterocyclic carbene of the 2,2′-(1H-2λ3,3λ4-imidazole-1,3-diyl)dicarboxylate ...
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Conformationally-Locked C-Glycosides: Tuning Aglycone Interactions for Optimal Cheperone Behaviour in Gaucher Fibroblasts
(Royal Society of Chemistry, 2016)A series of conformationally locked C-glycosides based on the 3-aminopyrano[3,2-b]pyrrol-2(1H)-one (APP) scaffold has been ...
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Conformationally-locked N -glycosides: Exploiting long-range non-glycone interactions in the design of pharmacological chaperones for Gaucher disease
(Elsevier, 2015)Pyranoid-type glycomimetics having a cis-1,2-fused glucopyranose–2-alkylsulfanyl-1,3-oxazoline (Glc-PSO) structure exhibit ...
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Continuous flow synthesis of PCN-222 (MOF-545) with controlled size and morphology: a sustainable approach for efficient production
(Royal Society of Chemistry, 2023-11-21)Zirconium-based MOFs, such as PCN-222 (MOF-545), have gained attention due to their regular porosity, tuneable pore size, ...
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Copper (I) Complexes of Zwitterionic Imidazolium- 2-Amidinates, A Promising Class of Electroneutral, Amidinate-Type ligands
(American Chemical Society, 2015)The first complexes containing imidazolium-2-amidinates as ligands (betaine-type adducts of imidazolium-based carbenes and ...
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Coupling of Aromatic Aldehydes with CO2Me-Substituted TpMe2Ir(III) Metallacyclopentadienes
(American Chemical Society, 2012)The fully CO2Me substituted aquo-iridacyclopentadiene 1 reacts with a variety of aromatic aldehydes, at 90–120 °C, with ...
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Cu(I) and Ag(I) complexes of two sterically demanding Xylyl-Substituted phosphine Ligands: Synthesis, Characterization, and structural examination
(Elsevier, 2023)Two sterically demanding tertiary phosphines, PiPr2Xyl and PtBu2Xyl, (Xyl = 2,6-dimethylphenyl), the latter reported here ...
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Cyclodextrin-based facial amphiphiles: Assessing the impact of the hydrophilic-lipophilic balance in the self-assembly, DNA complexation and gene delivery capabilities
(Royal Society of Chemistry, 2016)Exhaustive structure–efficacy relationship studies on nonviral gene delivery systems are often hampered by the ill-defined ...
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Cyclodextrin-based multivalent glycodisplays: Covalent and supramolecular conjugates to assess carbohydrate-protein interactions
(Royal Society of Chemistry (Great Britain), 2013)Covalent attachment of biorecognizable sugar ligands in several copies at precise positions of cyclomaltooligosaccharide ...
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Cyclodextrin-mediated Crystallization of Acid β-glucosidase in Complex with Amphiphilic Bicyclic Nojirimycin Analogues
(Royal Society of Chemistry, 2011)Cyclodextrin-based host-guest chemistry has been exploited to facilitate co-crystallization of recombinant human acid ...
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Cyclooctyne [60]fullerene hexakis adducts: a globular scaffold for copper-free click chemistry
(Royal Society of Chemistry, 2016)The synthesis of a new highly symmetric hexakis adduct of C60 appended with 12 cyclooctyne moieties has been carried out. ...
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Cytochrome c lysine acetylation regulates cellular respiration and cell death in ischemic skeletal muscle
(Springer Nature, 2023)Skeletal muscle is more resilient to ischemia-reperfusion injury than other organs. Tissue specific post-translational ...
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Cytochrome c speeds up caspase cascade activation by blocking 14-3-3ε-dependent Apaf-1 inhibition
(Nature Publishing Group, 2018)Apoptosis is a highly regulated form of programmed cell death, essential to the development and homeostasis of multicellular ...
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Cytochrome c: Surfing Off of the Mitochondrial Membrane on the Tops of Complexes III and IV
(Elsevier, 2019)The proper arrangement of protein components within the respiratory electron transport chain is nowadays a matter of intense ...
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Deciphering of polycationic carbohydrate based non-viral gene delivery agents by ESI-LTQ-Orbitrap using CID/HCD pairwise tandem mass spectrometry
(Royal Society of Chemistry, 2016)For almost three decades, gene therapy has been gaining interest to efficiently treat some severe diseases. In such context, ...
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Design, synthesis and biological studies of a library of NK1-Receptor Ligands Based on a 5-arylthiosubstituted 2-amino-4,6-diaryl-3-cyano-4H-pyran core: Switch from antagonist to agonist effect by chemical modification
(Elsevier, 2017)A library of 5-arylthiosubstituted 2-amino-4,6-diaryl-3-cyano-4H-pyrans has been synthesized as a new family of non-peptide ...