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Artículo
Importance of the polarity of the glycosaminoglycan chain on the interaction with FGF-1
(Oxford University Press, 2014)
Heparin-like saccharides play an essential role in binding to the fibroblast growth factor (FGF)-1 and to their membrane receptors fibroblast growth factor receptor forming a ternary complex that is responsible of the ...
Artículo
Interactions between a Heparin Trisaccharide Library and FGF-1 Analyzed by NMR Methods
(MDPI, 2017-06-17)
FGF-1 is a potent mitogen that, by interacting simultaneously with Heparan Sulfate Glycosaminoglycan HSGAG and the extracellular domains of its membrane receptor (FGFR), generates an intracellular signal that finally leads ...