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Mostrando ítems 1-10 de 17
Artículo
Hydrogenation of imines catalysed by ruthenium(ii) complexes based on lutidine-derived CNC pincer ligands
(Royal Society of Chemistry (Great Britain), 2013)
The preparation of new Ru(ii) complexes incorporating fac-coordinated lutidine-derived CNC ligands is reported. These derivatives are selectively deprotonated by tBuOK at one of the methylene arms of the pincer, leading ...
Artículo
Glycodendritic structures: Tools to interact with DC-SIGN
(Universidade de São Paulo, 2013)
The key role of carbohydrates in many biological events has attracted the interest of the scientific community. This fact has demanded the access to new tools necessary to understand this role and the interaction of ...
Artículo
Multivalency in heterogeneous glycoenvironments: Hetero-glycoclusters, -glycopolymers and -glycoassemblies
(Royal Society of Chemistry (Great Britain), 2013)
Despite efficiently imitating functional ligand presentations in terms of valency and density, most of the reported multivalent carbohydrate prototypes barely reflect the inherent heterogeneity of biological systems, ...
Artículo
Novel bis (1,3,2-diazaphospholidine) ligands for asymmetric catalysis
(American Chemical Society, 2013)
A family of modularly designed chiral bis(1,3,2-diazaphospholidines) with N-aryl substituents (NP-PN) is reported. These compounds have been prepared in two steps from readily available (R,R)-1,2-diaminocyclohexane and ...
Artículo
Catalytic amine-borane dehydrogenation by a PCP-pincer palladium complex: A combined experimental and DFT analysis of the reaction mechanism
(Royal Society of Chemistry (Great Britain), 2013)
Catalytic dehydrogenation of ammonia-borane (NH3·BH 3, AB) and dimethylamine borane (NHMe2·BH 3, DMAB) by the PdII complex [(tBuPCP)Pd(H 2O)]PF6 [tBuPCP = 2,6-C6H 3(CH2PtBu2)2] leads to oligomerization and formation of ...
Artículo
Highly enantioselective hydrogenation of 1-alkylvinyl benzoates: A simple, nonenzymatic access to chiral 2-alkanols
(John Wiley & Sons, 2013)
Going chiral! Highly enantioselective catalytic hydrogenations of enol esters 1 by using a Rh catalyst bearing a POP ligand are described (see scheme; NBD=norbornadiene). The catalytic system has a broad scope and allows ...
Artículo
Asymmetric organocatalytic Strecker-type reactions of aliphatic N,N-dialkylhydrazones
(Royal Society of Chemistry (Great Britain), 2013)
The enantioselective organocatalytic Strecker-type reaction of aliphatic N,N-dialkylhydrazones is presented. Using trimethylsilyl cyanide (TMSCN) as the cyanide source, the reaction can be efficiently catalyzed by a ...
Artículo
Cyclodextrin-based multivalent glycodisplays: Covalent and supramolecular conjugates to assess carbohydrate-protein interactions
(Royal Society of Chemistry (Great Britain), 2013)
Covalent attachment of biorecognizable sugar ligands in several copies at precise positions of cyclomaltooligosaccharide (cyclodextrin, CD) macrocycles has proven to be an extremely flexible strategy to build multivalent ...
Artículo
Selective carbohydrate-lectin interactions in covalent graphene- and SWCNT-based molecular recognition systems
(Royal Society of Chemistry, 2013)
Two new protein recognition systems have been prepared by covalent functionalization of few-layer graphene and SWCNTs with α-D-mannosyl dendrons. A glycodendron, bearing three mannose moieties on the periphery for effective ...
Artículo
Synthesis of chondroitin/dermatan sulfate-like oligosaccharides and evaluation of their protein affinity by fluorescence polarization
(Royal Society of Chemistry (Great Britain), 2013)
Here, we present a novel approach for the chemical synthesis of chondroitin and dermatan sulfate oligosaccharides. A key point of this strategy is the preparation and use of an N-trifluoroacetyl galactosamine building block ...