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Mostrando ítems 1-10 de 34
Artículo
Chemoenzymatic synthesis and radical scavenging of sulfated hydroxytyrosol, tyrosol, and acetylated derivatives
(American Chemical Society, 2019-07-03)
Potential metabolites of bioactive compounds are important for their biological activities and as authentic standards for metabolic studies. The phenolic compounds contained in olive oil are an important part of the human ...
Artículo
Preparation of Chitosan-supported Urea Materials and their Application in Some Organocatalytic Procedures
(Elsevier, 2018)
An efficient and mild procedure was developed for the preparation of three chitosan-supported ureas containing electron-withdrawing groups. These catalysts were characterized and employed as organocatalysts in different ...
Artículo
Isolation and identification of minor secoiridoids and phenolic components from thermally treated olive oil by-products
(Elsevier, 2015-11-15)
The application of an industrial process based on the hydrothermal treatment of 160 °C/60 min of alperujo, a by-product of olive oil extraction, allows the formation of a liquid phase containing a high concentration of ...
Artículo
Toward a Suitable Structural Analysis of Gene Delivery Carrier Based on Polycationic Carbohydrates by Electron Transfer Dissociation Tandem Mass Spectrometry
(Elsevier, 2016)
Polycationic carbohydrates represent an attractive class of biomolecules for several applications and particularly as non viral gene delivery vectors. In this case, the establishment of structure-biological activity ...
Artículo
Preparation of water-soluble glycopolymers derived from five-membered iminosugars
(Elsevier, 2019-10)
Iminosugars are carbohydrate mimetics that constitute the main group of oligosaccharide processing enzyme inhibitors. They play an important role in cell-cell recognition processes, thereby presenting a wide range ...
Artículo
Molecular Determinants for Cyclo-oligosaccharide-based Nanoparticle-mediated Effective siRNA Transfection
(Future Medicine Ltd., 2017)
Aim: To study the structural requirements that a cyclooligosaccharide-based nanoparticle must fulfill to be an efficient siRNA transfection vector. Materials & methods: siRNA protection from degradation by RNAses, transfection ...
Artículo
Selenium and sulphur derivatives of hydroxytyrosol: inhibition of lipid peroxidation in liver microsomes of vitamin E-deficient rats
(Springer Nature, 2019)
Purpose: The objective of this study was to evaluate the capacity of modified phenols synthesized from hydroxytyrosol, a natural olive oil phenol, specifically those containing a selenium or sulphur group, to inhibit lipid ...
Artículo
Dual drug-loaded halloysite hybrid-based glycocluster for sustained release of hydrophobic molecules
(Royal Society of Chemistry, 2016)
A dual drug-loaded HNT–CD glycocluster delivery system based on halloysite nanotubes and carbohydrate functionalized cyclodextrin was developed by a green protocol using solvent-free microwave irradiation. The nanohybrid ...
Artículo
Selenium and Sulphur Derivatives of Hydroxytyrosol: Inhibition of Lipid Peroxidation in Liver Microsomes of Vitamin E-deficient Rats
(Springer Nature, 2019)
Purpose: The objective of this study was to evaluate the capacity of modified phenols synthesized from hydroxytyrosol, a natural olive oil phenol, specifically those containing a selenium or sulphur group, to inhibit lipid ...
Artículo
Bifunctional Squaramide Organocatalysts for the Asymmetric Addition of Formaldehyde tert-Butylhydrazone to Simple Aldehydes
(Wiley-Blackwell, 2018)
The nucleophilic addition of formaldehyde tert-butylhydrazone to simple aldehydes (a formal hetero-carbonyl–ene reaction) can be performed with good reactivity and excellent enantioselectivity by virtue of the dual ...