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Artículo
Toward fluorinated aminoglycosides: Structural studies of phenylhydrazine condensation with carbohydrate derivatives
(Georg Thieme Verlag, 2013)
The reaction of phenylhydrazine with a sugar dialdehyde in water, as a key step for the synthesis of the 3-amino-3-deoxy-d-glucose moiety contained in kanamycin, has been revisited. Structural studies (IR and NMR as well ...
Artículo
Preparation of Chitosan-supported Urea Materials and their Application in Some Organocatalytic Procedures
(Elsevier, 2018)
An efficient and mild procedure was developed for the preparation of three chitosan-supported ureas containing electron-withdrawing groups. These catalysts were characterized and employed as organocatalysts in different ...
Artículo
Tacrine-O-protected phenolics heterodimers as multitarget-directed ligands against Alzheimer's disease: Selective subnanomolar BuChE inhibitors
(Elsevier, 2019-11-01)
Concerned by the devastating effects of Alzheimer's disease, and the lack of effective drugs, we have carried out the design of a series of tacrine-phenolic heterodimers in order to tackle the multifactorial nature of the ...
Artículo
Synthesis of hyperpolarizable biomaterials at molecular level based on pyridinium-chitosan complexes
(Universidade Federal do Espírito Santo, 2015)
Potential NLO-phore materials based on chitosan are described for the first time in this study. A series of fluorescent and quaternized pyridinium– chitosan derivatives have been synthesized by reaction of this polymer ...