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Artículo
Binding of DNA by a dinitro-diester calix[4]arene: Denaturation and condensation of DNA
(Elsevier, 2015)
A study of a dinitro-diester calix[4]arene (5,17-(3-nitrobenzylideneamino)-11,23-di-tert-butyl-25,27-diethoxycarbonyl methyleneoxy-26,28-dihydroxycalix[4]arene) interaction with calf-thymus DNA was carried out using several ...
Artículo
Biocompatible DNA/5-fluorouracil-gemini surfactant-functionalized gold nanoparticles as promising vectors in lung cancer therapy
(Multidisciplinary Digital Publishing Institute (MDPI), 2021)
The design and preparation of novel nanocarriers to transport cancer drugs for chemotherapy purposes is an important line of research in the medical field. A new 5-fluorouracil (5-Fu) transporter was designed based on the ...
Artículo
Metallo-Liposomes Derived from the [Ru(bpy)3]2+ Complex as Nanocarriers of Therapeutic Agents
(Multidisciplinary Digital Publishing Institute, 2021)
The obtaining of nanocarriers of gene material and small drugs is still an interesting research line. Side-effects produced by the toxicity of several pharmaceutics, the high concentrations needed to get therapeutic effects, ...
Artículo
DNA conformational changes induced by cationic gemini surfactants: the key to switching DNA compact structures into elongated forms
(Royal Society of Chemistry, 2015)
The DNA conformational changes induced by different members of the N,N0-bis(dimethyldodecyl)-a-ualkanediammonium dibromide series (m-s-m, m ¼ 12, s ¼ 3 and 6) and the analogous series of hexadecyl gemini surfactants (m ...
Artículo
AuNPs-DNA non-covalent interactions: improve of some studies and new avenues of research from negative results
(Universidade Federal do Espírito Santo, 2013)
Due to their chemical stability, high biocompatibility, excellent structural, optical, magnetic and catalytic properties, gold nanoparticles (AuNPs) have been widely used as therapeutics, delivery agents and transfection ...
Artículo
Use of Nanoparticles to Prevent Resistance to Antibiotics—Synthesis and Characterization of Gold Nanosystems Based on Tetracycline
(Multidisciplinary Digital Publishing Institute (MDPI), 2022)
Antimicrobial resistance (AMR) is a serious public health problem worldwide which, according to the World Health Organization (WHO), requires research into new and more effective drugs. In this work, both gold nanoparticles ...