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      p53 and FBXW7: Sometimes Two Guardians Are Worse than One 

      Galindo Moreno, María; Giráldez Macías, Servando; Limón Mortés, María Cristina; Belmonte Fernández, Alejandro; Sáez, Carmen; Japón, Miguel Ángel; Tortolero García, María Dolores; Romero Portillo, Francisco (MDPI, 2020)
      Too much of a good thing can become a bad thing. An example is FBXW7, a well-known tumor suppressor that may also contribute ...
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      βTrCP controls the lysosome-mediated degradation of CDK1, whose accumulation correlates with tumor malignancy 

      Herrero Ruiz, Joaquín; Mora Santos, María del Mar; Giraldez Macias, Servando; Sáez Torres, Carmen; Romero Portillo, Francisco; Japón Rodríguez, Miguel Ángel (Impact Journals, 2014)
      n mammals, cell cycle progression is controlled by cyclin-dependent kinases, among which CDK1 plays important roles in the ...