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Mostrando ítems 1-10 de 11
Artículo
Cell type-dependent variations in the subcellular distribution of alpha-mannosidase I and II
(Rockefeller University Press, 1993)
alpha-mannosidases I and II (Man I and II) are resident enzymes of the Golgi complex involved in oligosaccharide processing during N-linked glycoprotein biosynthesis that are widely considered to be markers of the cis- and ...
Artículo
Presence of terminal N-acetylgalactosamine residues in subregions of the endoplasmic reticulum is influenced by cell differentiation in culture
(The American Society for Biochemistry and Molecular Biology, 1991)
Using Helix pomatia lectin as a specific probe for terminal, nonreducing N-acetylgalactosamine residues, glycoprotein precursors bearing newly initiated O-linked oligosaccharides have been localized in the lumen of the ...
Artículo
Trimeric G proteins modulate the dynamic interaction of PKAII with the Golgi complex
(The Company of Biologists Ltd, 1999)
The Golgi complex represents a major subcellular location of protein kinase A (PKA) concentration in mammalian cells where it has been previously shown to be involved in vesicle-mediated protein transport processes. We ...
Artículo
Protein kinase A activity is required for the budding of constitutive transport vesicles from the trans-Golgi network
(National Academy of Sciences of the USA, 1997)
We have examined the role played by protein kinase A (PKA) in vesicle-mediated protein transport from the trans-Golgi network (TGN) to the cell surface. In vivo this transport step was inhibited by inhibitors of PKA catalytic ...
Artículo
Effect of protein kinase a activity on the association of ADP-ribosylation factor 1 to Golgi membranes
(The American Society for Biochemistry and Molecular Biology, 2000)
The small GTP-binding protein ADP-ribosylation factor 1 (ARF1) is an essential component of the molecular machinery that catalyzes the formation of membranebound transport intermediates. By using an in vitro assay that ...
Artículo
Trimeric G proteins regulate the cytosol-induced redistribution of Golgi enzymes into the endoplasmic reticulum
(Company of Biologists Ltd, 1995)
Streptolysin O-permeabilized cells incubated with a high concentration (5-10 mg/ml) of cytosolic proteins and ATPgenerating system exhibit redistribution into the endoplasmic reticulum (ER) of Golgi integral proteins ...
Artículo
Golgi structural stability and biogenesis depend on associated PKA activity
(The Company of Biologists, 2006)
The mammalian Golgi complex consists of stacks of cisternae linked laterally into a continuous perinuclear ribbon structure. Protein kinase A is stably associated with the Golgi complex during interphase. To analyze its ...
Artículo
A Regulatory Role for cAMP-dependent Protein Kinase in Protein Traffic along the Exocytic Route
(The American Society for Biochemistry and Molecular Biology, 1996)
The influence of protein kinase A activity on transport of newly synthesized vesicular stomatitis virus G glycoprotein along the exocytic pathway was examined. Transport of vesicular stomatitis virus G glycoprotein ...
Artículo
Precursors of chondroitin sulfate proteoglycan are segregated within a subcompartment of the chondrocyte endoplasmic reticulum
(Rockefeller University Press, 1989)
Immunocytochemical methods were used at the levels of light and electron microscopy to examine the intracellular compartments of chondrocytes involved in extracellular matrix biosynthesis. The results of our studies provide ...