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Mostrando ítems 91-100 de 275
Artículo
The PARP inhibitor Olaparib disrupts base excision repair of 5-aza-2′-deoxycytidine lesions
(Oxford University Press, 2014)
Decitabine (5-aza-21-deoxycytidine, 5-azadC) is used in the treatment of Myelodysplatic syndrome (MDS) and Acute Myeloid Leukemia (AML). Its mechanism of action is thought to involve reactivation of genes implicated in ...
Tesis Doctoral
Caracterización de un subcompartimento proteolítico en el retículo endoplásmico de condrocitos
(1996)
LOS CONDROCITOS DE POLLO EN CULTIVO SINTETIZAN EL PROTEOGLICANO AGRECAN COMO UN PRECURSOR DE 370 KDA QUE ES GLICOSILADO Y SECRETADO AL MEDIO DE CULTIVO CON UNA VIDA MEDIA DE 30 MINUTOS. HEMOS DEMOSTRADO CON ESTUDIOS ...
Artículo
Dietary fatty acids in postprandial triglyceride-rich lipoproteins modulate human monocyte-derived dendritic cell maturation and activation
(MDPI, 2020)
Dietary fatty acids have been demonstrated to modulate systemic inflammation and induce the postprandial inflammatory response of circulating immune cells. We hypothesized that postprandial triglyceride-rich lipoproteins ...
Artículo
Identification of the Bioavailable Peptidome of Chia Protein Hydrolysate and the In Silico Evaluation of Its Antioxidant and ACE Inhibitory Potential
(American Chemical Society, 2024)
The incorporation of novel, functional, and sustainable foods in human diets is increasing because of their beneficial effects and environmental-friendly nature. Chia (Salvia hispanica L.) has proved to be a suitable ...
Artículo
Crosslinking assay to study a specific cargo-coat interaction through a transmembrane receptor in the secretory pathway
(Public Library of Science, 2022)
Intracellular trafficking through the secretory organelles depends on transient interactions between cargo proteins and transport machinery. Cytosolic coat protein complexes capture specific luminal cargo proteins for ...
Artículo
The Emp24 complex recruits a specific cargo molecule into endoplasmic reticulum-derived vesicles
(Rockefeller University Press, 2000)
Members of the yeast p24 family, including Emp24p and Erv25p, form a heteromeric complex re- quired for the efficient transport of selected proteins from the endoplasmic reticulum (ER) to the Golgi ap- paratus. The ...
Artículo
Niacin and olive oil promote skewing to the M2 phenotype in bone marrow-derived macrophages of mice with metabolic syndrome
(Royal Society of Chemistry, 2016)
Metabolic syndrome (MetS) is associated with obesity, dyslipemia, type 2 diabetes and chronic low-grade inflammation. The aim of this study was to determine the role of high-fat low-cholesterol diets (HFLCDs) rich in SFAs ...
Artículo
Isolation, characterization and antitumour properties of the 1,2-propylenediaminetetraacetate-trans-diaqua-copper(II)
(Hindawi Publishing Corporation, 2000)
A trans-diaquacomplex formed by copper(II) sulphate and the sequestering polyamminopolycarboxylic ligand 1,2-propylenediaminetetraacetic acid (PDTA) has been isolated and characterized by chemical analysis, titrimetry, ...
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