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Mostrando ítems 1-10 de 16
Artículo
Presence of terminal N-acetylgalactosamine residues in subregions of the endoplasmic reticulum is influenced by cell differentiation in culture
(The American Society for Biochemistry and Molecular Biology, 1991)
Using Helix pomatia lectin as a specific probe for terminal, nonreducing N-acetylgalactosamine residues, glycoprotein precursors bearing newly initiated O-linked oligosaccharides have been localized in the lumen of the ...
Artículo
Trimeric G proteins modulate the dynamic interaction of PKAII with the Golgi complex
(The Company of Biologists Ltd, 1999)
The Golgi complex represents a major subcellular location of protein kinase A (PKA) concentration in mammalian cells where it has been previously shown to be involved in vesicle-mediated protein transport processes. We ...
Artículo
Protein kinase A activity is required for the budding of constitutive transport vesicles from the trans-Golgi network
(National Academy of Sciences of the USA, 1997)
We have examined the role played by protein kinase A (PKA) in vesicle-mediated protein transport from the trans-Golgi network (TGN) to the cell surface. In vivo this transport step was inhibited by inhibitors of PKA catalytic ...
Artículo
Effect of protein kinase a activity on the association of ADP-ribosylation factor 1 to Golgi membranes
(The American Society for Biochemistry and Molecular Biology, 2000)
The small GTP-binding protein ADP-ribosylation factor 1 (ARF1) is an essential component of the molecular machinery that catalyzes the formation of membranebound transport intermediates. By using an in vitro assay that ...
Tesis Doctoral
Papel de la actividad de la proteína quinasa A(PKA) en el mantenimiento estructural y biogénesis del complejo de Golgi
(2007)
El complejo de Golgi es un lugar de concentración preferente de PKA en células mamíferos y su actividad modula diferentes pasos del tráfico intracelular. Dado que la arquitectura del orgánulo depende del balance entre ...
Tesis Doctoral
Regulación de la estructura y función del complejo de Golgi por factores citosólicos y proteínas G heterotriméricas
(1996)
Las células eucariotas están organizadas en una serie de compartimentos delimitados por membranas lipídicas. En cada comportamiento se realizan actividades características, que son la expresión funcional de las moléculas ...
Artículo
Trimeric G proteins regulate the cytosol-induced redistribution of Golgi enzymes into the endoplasmic reticulum
(Company of Biologists Ltd, 1995)
Streptolysin O-permeabilized cells incubated with a high concentration (5-10 mg/ml) of cytosolic proteins and ATPgenerating system exhibit redistribution into the endoplasmic reticulum (ER) of Golgi integral proteins ...
Tesis Doctoral
Caracterización de un subcompartimento proteolítico en el retículo endoplásmico de condrocitos
(1996)
LOS CONDROCITOS DE POLLO EN CULTIVO SINTETIZAN EL PROTEOGLICANO AGRECAN COMO UN PRECURSOR DE 370 KDA QUE ES GLICOSILADO Y SECRETADO AL MEDIO DE CULTIVO CON UNA VIDA MEDIA DE 30 MINUTOS. HEMOS DEMOSTRADO CON ESTUDIOS ...
Tesis Doctoral
Análisis de la función y la regulación de ArfGAP1
(2015-09-25)
Una de las características más significativas de la célula eucariota es el incesante tráfico vesicular que acontece entre sus orgánulos. A pesar de ello, y con el fin de mantener su propia identidad, cada compartimento ...
Artículo
Golgi structural stability and biogenesis depend on associated PKA activity
(The Company of Biologists, 2006)
The mammalian Golgi complex consists of stacks of cisternae linked laterally into a continuous perinuclear ribbon structure. Protein kinase A is stably associated with the Golgi complex during interphase. To analyze its ...