Artículo
Bimodal Nd-Doped LuVO4 Nanoprobes Functionalized with Polyacrilic Acid for X-Ray Computed Tomography and NIR Luminescent Imaging
Autor/es | Núñez Álvarez, Nuria Ofelia
Cussó, Fernando Cantelar, Eugenio Martín Gracia, Beatriz Martínez de la Fuente, Jesús Corral Sousa, Ariadna Balcerzyk, Marcin Ocaña Jurado, Manuel |
Departamento | Universidad de Sevilla. Departamento de Química Inorgánica |
Fecha de publicación | 2020 |
Fecha de depósito | 2020-06-17 |
Publicado en |
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Resumen | Uniform Nd3+-doped LuVO4 nanophosphors have been synthesized for the first time in literature by using a poliol-based method at 120 °C from Nd3+ and vanadate precursors. After optimizing the Nd doping level, these phosphors ... Uniform Nd3+-doped LuVO4 nanophosphors have been synthesized for the first time in literature by using a poliol-based method at 120 °C from Nd3+ and vanadate precursors. After optimizing the Nd doping level, these phosphors present intense luminescence in the near-infrared biological windows. The X-ray attenuation capacity of the optimum nanophosphor has been found to be higher than that of a commercial X-ray computed tomography contrast agent. After surface coating with polyacrylic acid, such nanoparticles present high colloidal stability in physiological pH medium and high cell viability. Because of these properties, the developed Nd3+-doped LuVO4 nanoparticles have potential applications as a bimodal probe for NIR luminescent bioimaging and X-ray computed tomography |
Identificador del proyecto | RTI2018-094426-B-I00
MAT2016-75716-C2-2-R |
Cita | Núñez Álvarez, N.O., Cussó, F., Cantelar, E., Martín Gracia, B., Martínez de la Fuente, J., Corral Sousa, A.,...,Ocaña Jurado, M. (2020). Bimodal Nd-Doped LuVO4 Nanoprobes Functionalized with Polyacrilic Acid for X-Ray Computed Tomography and NIR Luminescent Imaging. Nanomaterials, 10 (1), 149. |
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