dc.creator | Álvarez Molina, Rafael | es |
dc.creator | Muñoz-Piña, Sandra | es |
dc.creator | González, María U. | es |
dc.creator | Izquierdo-Barba, Isabel | es |
dc.creator | Fernández-Martínez, Iván | es |
dc.creator | Rico-Gavira, Víctor Joaquín | es |
dc.creator | Arcos, Daniel | es |
dc.creator | García-Valenzuela, Aurelio | es |
dc.creator | Palmero Acebedo, Alberto | es |
dc.creator | Vallet-Regí, María | es |
dc.creator | Rodríguez González-Elipe, Agustín | es |
dc.creator | García-Martín, José María | es |
dc.date.accessioned | 2020-02-25T16:31:18Z | |
dc.date.available | 2020-02-25T16:31:18Z | |
dc.date.issued | 2019 | |
dc.identifier.citation | Álvarez Molina, R., Muñoz-Piña, S., González, M.U., Izquierdo-Barba, I., Fernández-Martínez, I., Rico-Gavira, V.J.,...,García-Martín, J.M. (2019). Antibacterial Nanostructured Ti Coatings by Magnetron Sputtering: From Laboratory Scales to Industrial Reactors. Nanomaterials, 9 (9), 1217-. | |
dc.identifier.issn | 2079-4991 | es |
dc.identifier.uri | https://hdl.handle.net/11441/93617 | |
dc.description.abstract | Based on an already tested laboratory procedure, a new magnetron sputtering methodology to simultaneously coat two-sides of large area implants (up to ~15 cm2) with Ti nanocolumns in industrial reactors has been developed. By analyzing the required growth conditions in a laboratory setup, a new geometry and methodology have been proposed and tested in a semi-industrial scale reactor. A bone plate (DePuy Synthes) and a pseudo-rectangular bone plate extracted from a patient were coated following the new methodology, obtaining that their osteoblast proliferation efficiency and antibacterial functionality were equivalent to the coatings grown in the laboratory reactor on small areas. In particular, two kinds of experiments were performed: Analysis of bacterial adhesion and biofilm formation, and osteoblasts–bacteria competitive in vitro growth scenarios. In all these cases, the coatings show an opposite behavior toward osteoblast and bacterial proliferation, demonstrating that the proposed methodology represents a valid approach for industrial production and practical application of nanostructured titanium coatings. | es |
dc.description.sponsorship | EU-FEDER and the MINECO-AEI 201560E055 | es |
dc.description.sponsorship | EU-FEDER and the MINECO-AEI MAT2014-59772-C2-1-P | es |
dc.description.sponsorship | EU-FEDER and the MINECO-AEI MAT2016-75611-R | es |
dc.description.sponsorship | EU-FEDER and the MINECO-AEI MAT2016-79866-R | es |
dc.description.sponsorship | EU-FEDER and the MINECO-AEI MAT2015-69035-REDC | es |
dc.description.sponsorship | University of Seville (Spain) V and VI PPIT-US | es |
dc.description.sponsorship | MINECO CSIC13-4E-1794 | es |
dc.format | application/pdf | es |
dc.language.iso | eng | es |
dc.publisher | MDPI | es |
dc.relation.ispartof | Nanomaterials, 9 (9), 1217-. | |
dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 Internacional | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | * |
dc.subject | Magnetron sputtering | es |
dc.subject | Oblique angle deposition | es |
dc.subject | Nanostructured titanium thin films | es |
dc.subject | Antibacterial coatings | es |
dc.subject | Osteoblast proliferation | es |
dc.subject | Industrial scale | es |
dc.title | Antibacterial Nanostructured Ti Coatings by Magnetron Sputtering: From Laboratory Scales to Industrial Reactors | es |
dc.type | info:eu-repo/semantics/article | es |
dcterms.identifier | https://ror.org/03yxnpp24 | |
dc.type.version | info:eu-repo/semantics/publishedVersion | es |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | es |
dc.contributor.affiliation | Universidad de Sevilla. Departamento de Física Aplicada I | es |
dc.contributor.affiliation | Universidad de Sevilla. Departamento de Química Inorgánica | es |
dc.relation.projectID | AEI 201560E055 | es |
dc.relation.projectID | MAT2014-59772-C2-1-P | es |
dc.relation.projectID | MAT2016-75611-R | es |
dc.relation.projectID | MAT2016-79866-R | es |
dc.relation.projectID | MAT2015-69035-REDC | es |
dc.relation.projectID | CSIC13-4E-1794 | es |
dc.relation.publisherversion | https://www.mdpi.com/2079-4991/9/9/1217 | es |
dc.identifier.doi | 10.3390/nano9091217 | es |
dc.contributor.group | Universidad de Sevilla. FQM196: Nanotecnología en Superficies y Plasma | es |
idus.format.extent | 13 p. | es |
dc.journaltitle | Nanomaterials | es |
dc.publication.volumen | 9 | es |
dc.publication.issue | 9 | es |
dc.publication.initialPage | 1217 | es |