dc.creator | Romero Ruiz, Manuel María | es |
dc.creator | Ríos-Santos, J.V. | es |
dc.creator | Ríos Carrasco, Blanca | es |
dc.date.accessioned | 2019-09-06T17:16:31Z | |
dc.date.available | 2019-09-06T17:16:31Z | |
dc.date.issued | 2019-05-09 | |
dc.identifier.citation | Romero Ruiz, M.M., Ríos-Santos, J.V. y Ríos Carrasco, B. (2019). Influence of a Novel Surface of Bioactive Implants on Osseointegration: A Comparative and Histomorfometric Correlation and Implant Stability Study in Minipigs. International Journal of Molecular Sciences, 20 (9), 1-14. | |
dc.identifier.issn | 1422-0067 | es |
dc.identifier.uri | https://hdl.handle.net/11441/89048 | |
dc.description.abstract | Purpose: The objective of this study was to assess the influence of a novel surface of dental implants (ContacTi®) on the osseointegration process in a minipig model. The surface was compared with other existing surfaces on the market (SLA® and SLActive®) by employing bone implant contact analysis (BIC) and implant stability. Method: Twelve minipigs were used with prior authorisation from an ethics committee. Three types of surfaces were tested: SLA® (sand-blasted acid-etched titanium), SLActive® (same but hydrophilic, performed under a nitrogen atmosphere), and ContacTi® (alumina particle bombardment of titanium, bioactivated when treated thermochemically) in 4.1 mm × 8 mm implants with internal connection and a polished neck. Twelve implants of each surface type (N = 36) were placed, sacrificing 1/3 of the animals at 2 weeks of placement, 1/3 at 4 weeks and the remaining 1/3 at 8 weeks. Numerical variables were compared with Analysis of Variance, and the correlation between ISQ and BIC was established with the Spearman’s rank correlation coefficient. Results: SLActive® and ContacTi® surfaces showed elevated osteoconductivity at 4 weeks, maintaining a similar evolution at 8 weeks (large amount of mature lamellar tissue with high maturity and bone quality). The SLA® surface showed slower maturation. The ISQ values in surgery were elevated (above 65), higher at necropsy and higher at 4 and 8 weeks in the SLA® group than in the other two (SLActive® and ContacTi®). No significant correlation was found between ISQ and BIC for each implant surface and necropsy time. Conclusion: The three surfaces analysed showed high RFA and BIC values, which were more favourable for the SLActive® and ContacTi® surfaces. No statistical correlation was found between the RFA and BIC values in any of the three surfaces analysed. | es |
dc.description.sponsorship | Research Foundation of the University of Seville Project Code 1871 | es |
dc.format | application/pdf | es |
dc.language.iso | eng | es |
dc.publisher | MDPI | es |
dc.relation.ispartof | International Journal of Molecular Sciences, 20 (9), 1-14. | |
dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 Internacional | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | * |
dc.subject | implant surface | es |
dc.subject | Bioactive Implants | es |
dc.subject | Oral implants | es |
dc.subject | Histomorfometric analytic | es |
dc.subject | minipigs | es |
dc.title | Influence of a Novel Surface of Bioactive Implants on Osseointegration: A Comparative and Histomorfometric Correlation and Implant Stability Study in Minipigs | es |
dc.type | info:eu-repo/semantics/article | es |
dc.type.version | info:eu-repo/semantics/publishedVersion | es |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | es |
dc.contributor.affiliation | Universidad de Sevilla. Departamento de Estomatología | es |
dc.identifier.doi | 10.3390/ijms20092307 | es |
dc.contributor.group | Universidad de Sevilla.CTS113: Investigación, Etiología y Patogenia Periodontal, Patología Oral y Enfermedades Musculares | es |
idus.format.extent | 14 | es |
dc.journaltitle | International Journal of Molecular Sciences | es |
dc.publication.volumen | 20 | es |
dc.publication.issue | 9 | es |
dc.publication.initialPage | 1 | es |
dc.publication.endPage | 14 | es |