dc.contributor.advisor | Castro Hernández, Elena De | es |
dc.contributor.advisor | Gañán-Calvo, Alfonso M. | es |
dc.creator | Arcos González Turmo, Irene de | es |
dc.date.accessioned | 2019-07-04T11:18:21Z | |
dc.date.available | 2019-07-04T11:18:21Z | |
dc.date.issued | 2019-06-11 | |
dc.identifier.citation | Arcos González Turmo, I.d. (2019). Forcing microbubbles in microfluidics. (Tesis Doctoral Inédita). Universidad de Sevilla, Sevilla. | |
dc.identifier.uri | https://hdl.handle.net/11441/87841 | |
dc.description.abstract | The present thesis is a compilation of three studies in the field of microfluidic, more concretely, the
generation of microbubbles and the effect that different applied forces have on them.
A microbubble generation state of the art in terms of applications, employed fluids, working regimes and
microfluidic devices is introduced in the first place. Several microfluidic devices: cross junction, TJunction,
planar and axisymmetric flow focusing are compared with regard to their operational woking
regime -bubbling, jetting or squeezing- and achievable microbubble size, as well as their fundamental
advantages and limitations.
In the second chapter, a novel swirl flow-focusing microfluidic axisymmetric device for the generation of
monodisperse microbubbles at high production rates is presented. By forcing a swirl effect on the liquid
stream, a more stable production, as well as a microbubble size reduction -up to 57% compared to the
axisymmetric flow focusing-, is achieved due to the enhanced gas meniscus stability. The swirl is shown
to expand the bounds of the jetting mode inhibiting the bubbling mode. An experimental study is
performed for various blade angles -0º, 40º, 60º and 80º- and numerous gas to liquid flow rate ratios,
validating previous numerical simulations and previous flow-focusing scaling law proposed by Gañán-
Calvo [Gañán-Calvo, Physical Review E, 2004, 69(2), 027301]. Chips with 60º blades exhibit the best
combination of swirl effect and robustness against perturbations.
Chapter three is devoted to the active control of microbubble size on planar flow-focusing devices by
means of an acoustic streaming or mechanical excitation. Few numerical studies have been reported so
far, despite the invaluable information that computational analysis can through on this topic. In this
chapter, the microbubble generation is numerically analyzed for an ample range of acoustic accelerations
and frequencies and for several contact angles. A bubble volume change of 20% when sweeping
between 25º and 120º was observed. The addition of an acoustic excitation showed a correlation between
the frequency and the highest amplitude that the system can absorbed without collapsing. Likewise,
bubble size increases with the excitation amplitude. A theoretical framework for the physics and
parametric description of that tuning is also presented.
Finally, the effect of the acoustic excitation, not on bubble generation, but on a pinned microbubble in the
low-energy regime is experimentally analyzed. Here, the goal is not to modify the bubble size, but to
characterize liquid properties based on the bubble oscillation for medical diagnosis application. The novel
Digital Holographic Microscope (DHM) is used for measuring the bubble interface movement and an
unwrapping and mode recognition code is specifically developed for this chapter. Modes shapes and
resonance frequencies were identified and related to the liquid surface tension to obtain a surface tension
approximation. At the moment, further noise-reduction procedures as well as a viscosity relation to the
bubble oscillation are being developed. | es |
dc.format | application/pdf | es |
dc.language.iso | eng | es |
dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 Internacional | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | * |
dc.title | Forcing microbubbles in microfluidics | es |
dc.type | info:eu-repo/semantics/doctoralThesis | es |
dcterms.identifier | https://ror.org/03yxnpp24 | |
dc.type.version | info:eu-repo/semantics/publishedVersion | es |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | es |
dc.contributor.affiliation | Universidad de Sevilla. Departamento de Ingeniería Aeroespacial y Mecánica de Fluidos | es |
idus.format.extent | 70 p. | es |