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dc.creatorPérez Pérez, María Estheres
dc.creatorCouso Liáñez, Inmaculada Concepciónes
dc.creatorCrespo, José Luises
dc.date.accessioned2017-12-20T16:28:19Z
dc.date.available2017-12-20T16:28:19Z
dc.date.issued2017
dc.identifier.citationPérez Pérez, M.E., Couso Liáñez, I.C. y Crespo, J.L. (2017). The TOR Signaling Network in the Model Unicellular Green Alga Chlamydomonas reinhardtii. Biomolecules, 7 (3), 54-54.
dc.identifier.issn2218-273Xes
dc.identifier.urihttp://hdl.handle.net/11441/67882
dc.description.abstractCell growth is tightly coupled to nutrient availability. The target of rapamycin (TOR) kinase transmits nutritional and environmental cues to the cellular growth machinery. TOR functions in two distinct multiprotein complexes, termed TOR complex 1 (TORC1) and TOR complex 2 (TORC2). While the structure and functions of TORC1 are highly conserved in all eukaryotes, including algae and plants, TORC2 core proteins seem to be missing in photosynthetic organisms. TORC1 controls cell growth by promoting anabolic processes, including protein synthesis and ribosome biogenesis, and inhibiting catabolic processes such as autophagy. Recent studies identified rapamycin-sensitive TORC1 signaling regulating cell growth, autophagy, lipid metabolism, and central metabolic pathways in the model unicellular green alga <i>Chlamydomonas reinhardtii</i>. The central role that microalgae play in global biomass production, together with the high biotechnological potential of these organisms in biofuel production, has drawn attention to the study of proteins that regulate cell growth such as the TOR kinase. In this review we discuss the recent progress on TOR signaling in algae.es
dc.description.sponsorshipEspaña, MINECO BFU2015-68216-Pes
dc.formatapplication/pdfes
dc.language.isoenges
dc.publisherMDPIes
dc.relation.ispartofBiomolecules, 7 (3), 54-54.
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Internacional*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subjecttarget of rapamycin (TOR)es
dc.subjectrapamycines
dc.subjectFKBP12es
dc.subjectChlamydomonases
dc.subjectalgaees
dc.subjectautophagyes
dc.subjectlipid metabolismes
dc.titleThe TOR Signaling Network in the Model Unicellular Green Alga Chlamydomonas reinhardtiies
dc.typeinfo:eu-repo/semantics/articlees
dc.type.versioninfo:eu-repo/semantics/publishedVersiones
dc.rights.accessrightsinfo:eu-repo/semantics/openAccesses
dc.contributor.affiliationUniversidad de Sevilla. Departamento de Bioquímica Vegetal y Biología Moleculares
dc.relation.projectIDBFU2015-68216-Pes
dc.relation.publisherversionhttps://doi.org/10.3390/biom7030054es
dc.identifier.doi10.3390/biom7030054es
idus.format.extent1 p.es
dc.journaltitleBiomoleculeses
dc.publication.volumen7es
dc.publication.issue3es
dc.publication.initialPage54es
dc.publication.endPage54es
dc.contributor.funderMinisterio de Economía y Competitividad (MINECO). España

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Attribution-NonCommercial-NoDerivatives 4.0 Internacional
Except where otherwise noted, this item's license is described as: Attribution-NonCommercial-NoDerivatives 4.0 Internacional