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dc.creatorContreras Chávez, Lourdes Paolaes
dc.creatorMelgoza Contreras, Luz Maríaes
dc.creatorAguilar de Leyva, Mercedes Ángelaes
dc.creatorCaraballo Rodríguez, Isidoroes
dc.date.accessioned2017-04-07T10:11:22Z
dc.date.available2017-04-07T10:11:22Z
dc.date.issued2012
dc.identifier.citationContreras Chávez, L.P., Melgoza Contreras, L.M., Aguilar de Leyva, M.Á. y Caraballo Rodríguez, I. (2012). Collaboration between HPMC and NaCMC in order to Reach the Polymer Critical Point in Theophylline Hydrophilic Matrices. Scientific World Journal, 2012 (ID 171292), 1-8.
dc.identifier.issn2356-6140es
dc.identifier.urihttp://hdl.handle.net/11441/57347
dc.description.abstractPercolation theory has been applied in order to study the existence of critical points as well as the possibility to find a “combined percolation threshold” for ternary hydrophilic matrices prepared with HPMC, NaCMC, and theophylline. For this purpose, different batches of ternary as well as binary hydrophilic matrices have been prepared. Critical points have been found for binary hydrophilic matrices between 21.5 and 31.3% (v/v) of HPMC and between 39 and 54% (v/v) of NaCMC, respectively. In a previous work carried out with the same polymers but a much more soluble drug (KCl), it was demonstrated the existence of a partial collaboration between the polymers in order to establish the gel layer. In this work, it has been observed for the first time the need of a minimum concentration of one of the matrix-forming polymer (between 10 and 20% v/v, approximately) for establishing an effective collaboration.es
dc.formatapplication/pdfes
dc.language.isoenges
dc.publisherHindawi Publishing Corporationes
dc.relation.ispartofScientific World Journal, 2012 (ID 171292), 1-8.
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Internacional*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.titleCollaboration between HPMC and NaCMC in order to Reach the Polymer Critical Point in Theophylline Hydrophilic Matriceses
dc.typeinfo:eu-repo/semantics/articlees
dcterms.identifierhttps://ror.org/03yxnpp24
dc.type.versioninfo:eu-repo/semantics/publishedVersiones
dc.rights.accessRightsinfo:eu-repo/semantics/openAccesses
dc.contributor.affiliationUniversidad de Sevilla. Departamento de Farmacia y Tecnología Farmacéuticaes
dc.contributor.affiliationUniversidad de Sevilla. Departamento de Química Inorgánicaes
dc.relation.publisherversionhttp://dx.doi.org/10.1100/2012/171292es
dc.identifier.doi10.1100/2012/171292es
idus.format.extent9 p.es
dc.journaltitleScientific World Journales
dc.publication.volumen2012es
dc.publication.issueID 171292es
dc.publication.initialPage1es
dc.publication.endPage8es

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