dc.creator | Casa Rivas, Luis Gonzalo de La | es |
dc.creator | Fernández del Olmo, Aarón | es |
dc.creator | Larrauri, Jose | es |
dc.creator | Mena, Auxiliadora | es |
dc.creator | Puentes, Andrea | es |
dc.creator | Quintero Sánchez, Esperanza | es |
dc.creator | Schmajuk, Nestor | es |
dc.date.accessioned | 2017-02-27T19:05:51Z | |
dc.date.available | 2017-02-27T19:05:51Z | |
dc.date.issued | 2012 | |
dc.identifier.citation | Casa Rivas, L.G.d.L., Fernández del Olmo, A., Larrauri, J., Mena, A., Puentes, A., Quintero Sánchez, E. y Schmajuk, N. (2012). Different effects of unexpected changes in environmental conditions on prepulse inhibition in rats and humans. Physiology & Behavior, 106 (4), 542-547. | |
dc.identifier.issn | 0031-9384 | es |
dc.identifier.uri | http://hdl.handle.net/11441/54951 | |
dc.description.abstract | The reduction of the startle response to an auditory stimulus caused by the presentation of another stimulus
of lower intensity closely preceding it, a phenomenon known as prepulse inhibition (PPI), can be modulated
by changes in dopaminergic activity. Schmajuk, Larrauri, De la Casa, and Levin (2009) demonstrated that this
dopaminergic modulation of PPI in rats can be influenced by manipulating the experimental context,
specifically by introducing changes in the ambient lighting condition that include novel elements. In this
paper we analyze the effects of introducing changes in context illumination on PPI in male rats (Experiment
1) and humans (Experiment 2). The results with rats showed a reduction of PPI when the illumination
condition switched from dark to light, but not from light to dark. In the experiment with human participants
the reduction of PPI occurred for both changes in illumination conditions. The animal experiment results are
interpreted in terms of competing exploratory behavior that appear when the context is illuminated after the
dark–light transition; while in the case of human participants a perceptual and/or attentional mechanism
after both illumination transitions is proposed, which may result in a reduced processing of the prepulse and
subsequent lower PPI. | es |
dc.description.sponsorship | Junta de Andalucía SEJ-02618 | es |
dc.description.sponsorship | Ministerio de Ciencia e Innovación de España PSI2009-7536 | es |
dc.format | application/pdf | es |
dc.language.iso | eng | es |
dc.publisher | Elsevier | es |
dc.relation.ispartof | Physiology & Behavior, 106 (4), 542-547. | |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | * |
dc.subject | Prepulse inhibition | es |
dc.subject | Novelty | es |
dc.subject | Dopamine | es |
dc.subject | Rats | es |
dc.subject | Humans | es |
dc.title | Different effects of unexpected changes in environmental conditions on prepulse inhibition in rats and humans | es |
dc.type | info:eu-repo/semantics/article | es |
dcterms.identifier | https://ror.org/03yxnpp24 | |
dc.type.version | info:eu-repo/semantics/acceptedVersion | es |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | es |
dc.contributor.affiliation | Universidad de Sevilla. Departamento de Psicología Experimental | es |
dc.relation.projectID | SEJ-02618 | es |
dc.relation.projectID | PSI2009-7536 | es |
dc.relation.publisherversion | http://dx.doi.org/10.1016/j.physbeh.2012.03.036 | es |
dc.identifier.doi | 10.1016/j.physbeh.2012.03.036 | es |
idus.format.extent | 6 p. | es |
dc.journaltitle | Physiology & Behavior | es |
dc.publication.volumen | 106 | es |
dc.publication.issue | 4 | es |
dc.publication.initialPage | 542 | es |
dc.publication.endPage | 547 | es |
dc.contributor.funder | Junta de Andalucía | |
dc.contributor.funder | Ministerio de Ciencia e Innovación (MICIN). España | |