dc.creator | Vargas Romero, Juan Pedro | es |
dc.creator | Díaz Argandoña, Estrella | es |
dc.creator | Portavella García, Manuel | es |
dc.creator | López García, Juan Carlos | es |
dc.date.accessioned | 2017-02-07T15:02:10Z | |
dc.date.available | 2017-02-07T15:02:10Z | |
dc.date.issued | 2016 | |
dc.identifier.citation | Vargas Romero, J.P., Díaz Argandoña, E., Portavella García, M. y López García, J.C. (2016). Animal models of maladaptive traits: disorders in sensorimotor gating and attentional quantifiable responses as possible endophenotypes. Frontiers in Psychology, 7 | |
dc.identifier.issn | 1664-1078 | es |
dc.identifier.uri | http://hdl.handle.net/11441/53789 | |
dc.description.abstract | Traditional diagnostic scales are based on a number of symptoms to evaluate and classify mental diseases. In many cases, this process becomes subjective, since the patient must calibrate the magnitude of his/her symptoms and therefore the severity of his/her disorder. A completely different approach is based on the study of the more vulnerable traits of cognitive disorders. In this regard, animal models of mental illness could be a useful tool to characterize indicators of possible cognitive dysfunctions in humans. Specifically, several cognitive disorders such as schizophrenia involve a dysfunction in the mesocorticolimbic dopaminergic system during development. These variations in dopamine levels or dopamine receptor sensibility correlate with many behavioral disturbances. These behaviors may be included in a specific phenotype and may be analyzed under controlled conditions in the laboratory. The present study provides an introductory overview of different quantitative traits that could be used as a possible risk indicator for different mental disorders, helping to define a specific endophenotype. Specifically, we examine different experimental procedures to measure impaired response in attention linked to sensorimotor gating as a possible personality trait involved in maladaptive behaviors. | es |
dc.description.sponsorship | Ministerio de Economía y Competitividad PSI2012- 32445 | es |
dc.format | application/pdf | es |
dc.language.iso | eng | es |
dc.publisher | Frontiers Media | es |
dc.relation.ispartof | Frontiers in Psychology, 7 | |
dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 Internacional | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | * |
dc.subject | Dopamine | es |
dc.subject | Endophenotype | es |
dc.subject | Latent inhibition | es |
dc.subject | Mental disorder | es |
dc.subject | Prepulse inhibition | es |
dc.title | Animal models of maladaptive traits: disorders in sensorimotor gating and attentional quantifiable responses as possible endophenotypes | es |
dc.type | info:eu-repo/semantics/article | es |
dcterms.identifier | https://ror.org/03yxnpp24 | |
dc.type.version | info:eu-repo/semantics/publishedVersion | es |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | es |
dc.contributor.affiliation | Universidad de Sevilla. Departamento de Psicología Experimental | es |
dc.relation.projectID | PSI2012- 32445 | es |
dc.relation.publisherversion | http://dx.doi.org/10.3389/fpsyg.2016.00206 | es |
dc.identifier.doi | 10.3389/fpsyg.2016.00206 | es |
idus.format.extent | 9 p. | es |
dc.journaltitle | Frontiers in Psychology | es |
dc.publication.volumen | 7 | es |
dc.publication.issue | | es |
dc.publication.endPage | 9 | es |
dc.contributor.funder | Ministerio de Economía y Competitividad (MINECO). España | |