Sutureless colic anastomoses with cyanoacrylates

Abstract

BACKGROUNO ANO AIMS. The present research Project has been made mainly with the idea of comparing the tensile strength values and histological answers of threetypes of colon anatomises: sutured with silk and sutureless anastomoses with 2-octyl-cyanocrylate and N-butyl-2-cyanoacrylate. Methods. 112 Wistar rats distributed into three groups of 35 animals and a last control group of 7 have been used for this. Group 1: silk, group 2:2-octyl-cyanocrylate, group 3: N-butyl-2-cyanoacrylate,group 4: Control group_. The following surgical interventions were practiced on them:A cross section of the colon,followed by: group 1: an end-to-end discontinuous suture anastomoses with Silk; group 2: sutureless anastomoses with 2-octyl-cyanocrylate;group 3:sutureless anastomoses With N-butyl-2-cyanoar1ylate. On the 10th, 20th, 30th, 40th and 50th days we proceeded to measure the anastomoses tensile strength value for each series.In the same period of time we carried out the following anatomic-pathological determinations: a) sharp inflammation; b) oedema; c) non-specif chronic inflammatory infiltrate; d) granulomatous inflammatory infiltrate to foreign e) fibrosis. Results.The results obtained indicate a greater anastomeses tensile strength for group 2 and 3. The anatomic-pathological values show a better response to anastomoses with adhesive than with conventional sutures. CONCLUSIONS. All these experimental results lead us to conclude that the cyanocrilates used to carry out sutureless anastomoses may be an n alternative to the handmade conventional anastomoses. Moreover they are easy to be implemented.