dc.creator | Miguel-Escuder, L. | es |
dc.creator | Rocha de Lossada, Carlos | es |
dc.creator | Sabater Cruz, Noelia | es |
dc.creator | Sánchez González, José María | es |
dc.creator | Spencer, Felipe | es |
dc.creator | Marín-Martínez, Sara | es |
dc.creator | Batlle-Ferrando, S. | es |
dc.creator | Carreras Castañer, X. | es |
dc.creator | Torras, J. | es |
dc.creator | Peraza-Nieves, Jorge | es |
dc.date.accessioned | 2024-06-10T11:23:10Z | |
dc.date.available | 2024-06-10T11:23:10Z | |
dc.date.issued | 2022 | |
dc.identifier.citation | Miguel-Escuder, L., Rocha de Lossada, C., Sabater Cruz, N., Sánchez González, J.M., Spencer, F., Marín-Martínez, S.,...,Peraza-Nieves, J. (2022). Use of nicergoline as adjunctive treatment of neurotrophic keratitis in routine clinical practice: a case series. Ocular Immunology and Inflammation, 30 (7-8), 1926-1930. https://doi.org/10.1080/09273948.2021.1976214. | |
dc.identifier.issn | 1744-5078 (electrónico) | es |
dc.identifier.issn | 0927-3948 (impreso) | es |
dc.identifier.uri | https://hdl.handle.net/11441/160157 | |
dc.description.abstract | Purpose: To describe the effectiveness and safety of nicergoline in patients with epithelial corneal defect or corneal ulcer due to neurotrophic keratitis. Methods: A prospective case series review was performed in 14 patients (14 eyes) with neurotrophic keratopathy who started treatment with nicergoline as an off-label prescription from January to November of 2020. Patients with a epithelial defect or corneal ulcer due to neurotrophic keratitis were treated with 10 mg of oral nicergoline twice daily. Results/Serial cases: Complete corneal healing was observed in 10 (71.4%) of the 14 patients after 25.6 ± 26.60 days (range 7-90) with nicergoline. In three (21.5%) patients the wound healing was not achieved (all of them with autoimmune disease), and one patient (7.1%) was lost to follow-up. Eleven patients (79%) were females; the average age at consultation was 69 years (44-96). The mean time between diagnosis and the starting of nicergoline was 10.92 ± 8.85 days (0-28). No adverse effects of nicergoline were observed in any subject. Conclusion: Nicergoline as an adjunctive treatment for neurotrophic keratitis showed a potential use in the healing of epithelial defect with a good tolerance in real-life clinical practice.
Introduction: | es |
dc.format | application/pdf | es |
dc.format.extent | 5 p. | es |
dc.language.iso | eng | es |
dc.publisher | TAYLOR & FRANCIS INC | es |
dc.relation.ispartof | Ocular Immunology and Inflammation, 30 (7-8), 1926-1930. | |
dc.rights | Atribución-NoComercial 4.0 Internacional | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc/4.0/ | * |
dc.subject | Nicergoline | es |
dc.subject | Neurotrophic keratitis | es |
dc.subject | Persistent corneal epithelial defect | es |
dc.subject | Corneal ulcer | es |
dc.title | Use of nicergoline as adjunctive treatment of neurotrophic keratitis in routine clinical practice: a case series | es |
dc.type | info:eu-repo/semantics/article | es |
dc.type.version | info:eu-repo/semantics/acceptedVersion | es |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | es |
dc.contributor.affiliation | Universidad de Sevilla. Departamento de Física de la Materia Condensada | es |
dc.relation.publisherversion | https://doi.org/10.1080/09273948.2021.1976214 | es |
dc.identifier.doi | 10.1080/09273948.2021.1976214 | es |
dc.journaltitle | Ocular Immunology and Inflammation | es |
dc.publication.volumen | 30 | es |
dc.publication.issue | 7-8 | es |
dc.publication.initialPage | 1926 | es |
dc.publication.endPage | 1930 | es |